CAS: 138-38-5; 4-Ethylbenzenesulfonamide

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上下游产品

CAS号97-94-9 三乙基硼 | CAS号701-34-8 4-溴苯磺酰胺 | CAS号1336-21-6 氨水 | CAS号16712-69-9 4-乙基苯磺酰氯 | CAS号17988-51-1 (3-ethylphenyl)... | CAS号100-41-4 乙苯 | CAS号110955-51-6 4-ethyl-N-(prop... | CAS号3168-01-2 乙酸己脲 | CAS号1565-17-9 4-乙酰基苯磺酰胺 | CAS号64329-90-4 4-ethyl-N-pheny...

📜(2-乙基-1,4-亚苯基)双(三甲基硅烷)置于acide Trifluoroacetique,Chlorure D'Aluminium,Chlorure De Sulfamoyle体系中,用 四氯化碳,二氯甲烷 用作溶剂,化学反应 30.0H,反应生成4-乙基苯磺酰胺
参考文献:氟代乙苯的原位和选择性官能化
标题:氟代乙苯的原位和选择性官能化
摘要:报道了一种用于氟和乙苯的间位官能化的原始的和区域选择性的方法.该方法涉及在锂存在于thf中作用作溶剂的情况下,使用三甲基氯硅烷对这些底物进行2,5-二甲硅烷基化.芳构化后,在2位进行单去甲硅烷基化,在5位上亲电取代三甲基甲硅烷基,间乙酰基,千里香酰基,苯甲酰基和碘代氟苯和乙苯,以及间氟或间乙苯磺酸的钠盐和以非常好的收率获得了3-氨基磺酰基氟苯.
Doi:10.1016/s0040-4020(01)81469-1

专利信息

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002040032-A1
优先权日:2000-07-07
标 题:Methods for stimulation of synthesis of synaptophysin in the central nervous system
发明人：GLASKY MICHELLE S; LAHIRI DEBOMOY K; FARLOW MARTIN R
摘要:A method of increasing the synthesis and/or secretion of synaptophysin comprises administering to a patient with a neurological disease or a patient at risk of developing a neurological disease an effective quantity of a purine derivative or analogue, a tetrahydroindolone derivative or analogue, or a pyrimidine derivative or analogue. If the compound is a purine derivative, the purine moiety can be guanine or hypoxanthine. The neurological disease can be a neurodegenerative disease such as Alzheimer's disease or a neurodevelopmental disorder such as Down's syndrome. Typically, the compound can pass through the blood-brain barrier. The purine moiety can be hypoxanthine or guanine. A particularly preferred purine derivative is N-4-carboxyphenyl-3-(6-oxohydropurin-9-yl) propanamide.

专利号:US-2002156277-A1
优先权日:2001-04-20
标题 :Synthesis and methods of use of purine analogues and derivatives
发明人：FICK DAVID B; FOREMAN MARK M; GLASKY ALVIN J
摘要:A purine derivative or analogue comprises a 9-atom bicyclic moiety, moiety A, linked through a linker L to a moiety B, where B is a carboxylic acid, a carboxylic acid ester, or a moiety of the structure N(Y 1 )—D, where Y 1 can be one of a variety of substituents, including hydrogen or alkyl, and D is a moiety that enhances the pharmacological effects, promotes absorption or blood-brain barrier penetration of the derivative or analogue. The moiety A has a six-membered ring fused to a five-membered ring. The moiety A can have one, two, or three nitrogen atoms in the five membered ring and has two nitrogen atoms in the six-membered ring. The moiety A can be a purine moiety. The moiety B can be one of a variety of moieties, including moieties having nootropic activity or other biological or physiological activity.

专利号:US-2004116453-A1
优先权日:2001-07-17
标 题 :Synthesis and methods of use pyrimidine analogues and derivatives
发明人：FICK DAVID B; FOREMAN MARK M; GLASKY ALVIN J
摘要:A pyrimidine derivative or analogue comprises an amino-substituted six-membered heterocyclic moiety, moiety A, linked through a linker L to a moiety B, where B is a carboxylic acid, a carboxylic acid ester, or a moiety of the structure N(Y 1 )-D, where Y 1 can be one of a variety of substituents, including hydrogen or alkyl, and D is a moiety that enhances the pharmacological effects, promotes absorption, or promotes blood-brain barrier penetration of the derivative or analogue. The moiety A can have two or three nitrogen atoms in the ring; typically, the moiety A is a pyrimidine moiety, with two nitrogen atoms in the ring. The moiety B can be one of a variety of moieties, including moieties having nootropic activity or other biological or physiological activity.

专利号:US-8916705-B2
优先权日:2011-10-14
标 题:Procaspase-activating compounds and compositions
发明人：HERGENROTHER PAUL J
权利人:UNIV ILLINOIS; TRUSTEES OF THE UNIVERSITY OF ILLILNOIS BOARD OF
摘要:The invention provides compounds and compositions useful for the modulation of certain enzymes. The compounds and compositions can induce of cell death, particularly cancer cell death. The invention also provides methods for the synthesis and use of the compounds and compositions, including the use of compounds and compositions in therapy for the treatment of cancer and selective induction of apoptosis in cells.