CAS: 120-36-5; 2-(2,4-Dichlorophenoxy)Propionic Acid

该化合物是一种选择性除草剂,主要用于控制不同作物的宽叶素杂草,属于苯氧除草剂家族,其特点是能够模仿植物激素,扰乱目标杂草的正常生长过程.化学结构具有一种与二氯苯氧化合物组相连的丙酸味,有助于其草药灭菌活动.二氯丙基通常在农业环境中应用,并可在可进行有效杂草管理的配方中找到.其行动方式包括抑制易感染植物的细胞分裂和延长.虽然它有效控制了杂草,但必须处理二氯丙酸,同时注意潜在的环境影响和对非目标有机物的毒性.管制评估确定了使用该二氯丙基酸的指南,以尽量减少对人类健康和生态系统的风险.与任何化学物质一样,适当的应用技术和遵守安全议定书对于确保有效和负责任地使用至关重要.

结构式图片

欧盟法规

统一分类与标签ECHA物质ECHA物质工作场所安全标识要求C&L通报REACH预注册废弃物危险特性清单

上下游产品

2-(2,4-dichlorophenoxy)propanoic acid methyl ester sodium 2,4-dichlorophenolate n-butyl 2-(2,4-dichlorophenoxy)propanoate brucine(R)-(+)-Methyl 2-(2,4-dichlorophenoxy)propionate oxy>-9-methylenebicyclononane(1R,6S,7S)-7-((R)-1-(2,4-dichlorophenoxy)ethyl)carbonyloxy-9-methylenebicyclo4.3.0nonane oxy>-9-methylenebicyclononane(1S,6R,7R)-7-((R)-1-(2,4-dichlorophenoxy)ethyl)carbonyloxy-9-methylenebicyclo4.3.0nonane (R)-2-(2,4-Dichloro-phenoxy)-propionic acid 1-methyl-heptyl ester

合成工艺路线路线简述

    2,4-二氯酚置于甲醇,Potassium Carbonate,Sodium Hydroxide体系中,用 水,丙酮 用作溶剂,化学反应生成2,4-滴丙酸
    参考文献:对映体富集 (R)-和 (S)-芳氧基链烷酸除草剂的化学酶合成
    标题:对映体富集 (R)-和 (S)-芳氧基链烷酸除草剂的化学酶合成
    摘要:对于最常用的除草剂家族之一,已经开发出一种通用且可持续的方法,该方法基于生物催化还原脱卤,然后进行简单的化学操作.一系列商业相关的目标分子已经以非常好的收率和中等至极好的对映选择性(对任一对映异构体)获得,无需色谱纯化和使用粗酶制剂.
    Doi:10.1002/ejoc.202200609

    海关参考信息

    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:EP-0609638-A1
    优先权日:1992-10-27
    标 题:Water soluble polymeric systems of phytohormones with slow release: synthesis and application
    发明人:TSATSAKIS ARISTIDIS; VLACHAKIS ELEUTERIOS IOANIS; SHTILMAN ISAAK MICHAIL; SHASHKOVA MICHAIL IRINA; ALLAKHVERDIEV SURKHAI RAGIM IN
    权利人:TSATSAKIS ARISTIDIS; VLACHAKIS ELEUTERIOS IOANIS; SHTILMAN ISAAK MICHAIL; SHASHKOVA MICHAIL IRINA; ALLAKHVERDIEV SURKHAI RAGIM IN
    摘要:Our discovery concerns the method of synthesis and the application of new chemical products for plant growing. These new products are polymeric derivatives of low molecular weight plant growth regulators and are characterized by slow release of the auxin from the polymeric carrier. By copolymerisation of allylic esters of the low molecular weight auxins with the acrylic (or the methylacrylic) acid and the following modification of the synthesized co-polymers of acids to their corresponding ammonium salts, water soluble polymeric auxins possesing optimal molecular weight and desirable (high) content of the low molecular weight auxin in the polymer were prepared. The method of synthesis and the final products fulfill the requirements of the preparation technology and of their application respectively. We suggest the application of the new products in agronomy (i.e. treatment of seeds, rootstocks, plants, scions, cutting etc) either by themselves or by combination of them with other chemicals. The chemical structure of the new products we discover is :n n    R = H-, -CH3, Au = auxin residue

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.
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    主要参考文献


    1: Matamoros V, Franco J. Assessing the use of sand, peat soil, and pine bark for the attenuation of polar pesticides from agricultural run-off: a bench-scale column experiment. Environ Sci Pollut Res Int. 2018 May 11. doi: 10.1007/s11356-018-2213-x. [Epub ahead of print] doi: 10.1021/acs.est.7b04252. Epub 2017 Sep 27. doi: 10.1016/j.scitotenv.2017.06.037. Epub 2017 Jun 20. doi: 10.1021/acs.jafc.6b05407. Epub 2017 Feb 7. doi: 10.1007/s11356-016-7516-1. Epub 2016 Oct 2. doi: 10.1016/j.watres.2016.08.057. Epub 2016 Aug 30. pii: E534. doi: 10.3390/ijerph13060534.
    8: Chen Z, Chen H, Zou Y, Wen Y. Stomatal behaviors reflect enantioselective phytotoxicity of chiral herbicide dichlorprop in Arabidopsis thaliana. Sci Total Environ. 2016 Aug 15;562:73-80. doi: 10.1016/j.scitotenv.2016.03.205. Epub 2016 Apr 17. doi: 10.1128/AEM.02600-15. Print 2016 Feb 1.
    10: Epp JB, Alexander AL, Balko TW, Buysse AM, Brewster WK, Bryan K, Daeuble JF, Fields SC, Gast RE, Green RA, Irvine NM, Lo WC, Lowe CT, Renga JM, Richburg JS, Ruiz JM, Satchivi NM, Schmitzer PR, Siddall TL, Webster JD, Weimer MR, Whiteker GT, Yerkes CN. The discovery of Arylex™ active and Rinskor™ active: Two novel auxin herbicides. Bioorg Med Chem. 2016 Feb 1;24(3):362-71. doi: 10.1016/j.bmc.2015.08.011. Epub 2015 Aug 19. doi: 10.1002/etc.3212. Epub 2016 Jan 8. Review. doi: 10.1016/j.aca.2015.03.037. Epub 2015 Mar 27. doi: 10.1016/j.scitotenv.2015.01.064. Epub 2015 Jan 31. doi: 10.1007/s11356-014-3534-z. Epub 2014 Sep 11. doi: 10.1155/2014/709036. Epub 2014 Mar 27.

    合成参考文献


    摘要:Desroches, J.; Paquin, J.-F., Science of Synthesis Knowledge Updates, (2016) 1, 384.
    摘要:Prehled Prumyslove Toxikologie; Organicke Latky, Marhold, J., Prague, Czechoslovakia, Avicenum, 1986, -(547), 1986
    摘要:Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases., 27(9)(50), 1983
    摘要:Roczniki Panstwowego Zakladu Higieny., 31(373), 1980 []
    摘要:Gigiena i Sanitariya. For English translation, see HYSAAV., 50(9)(22), 1985
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