CAS: 118994-89-1; Ethyl Oxazole-5-Carboxylate

相似化合物

118994-90-4 127232-41-1 118994-86-8

上下游产品

methyl is°Cyanate oxalic acid diethyl ester glyoxylic acid ethyl ester [(p-methylphenyl)sulfonylmethyl]isonitrile4-iodo-5-carbethoxyoxazole ethyl 2-chloro-1,3-oxazole-5-carboxylate 1,3-oxazol-5-ylmethanol 16H14N2O3SC16H14N2O3S

📜3-二氮杂-2-氧代丙酸乙酯 反应生成噁唑-5-羧酸乙酯
参考文献:Crews,Philip;Matthews,Thomas R.;Cahana,Emilio Q.;Adamczeski,Madeline
标题:Crews,Philip;Matthews,Thomas R.;Cahana,Emilio Q.;Adamczeski,Madeline

专利信息

专利号:US-2024309003-A1
优先权日:2021-05-04
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN; PANDYA BHAUMIK; KAPLAN ALAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.