CAS: 118-70-7; Pyrimidine-4,5,6-Triamine

相似化合物

49721-45-1 2164-84-3 13754-19-3

上下游产品

CAS号49721-45-1 4,5,6-三氨基嘧啶硫酸盐 | CAS号59150-27-5 4,6-二氨基-2-疏基-5-硝基嘧啶 | CAS号61908-15-4 5-亚硝基嘧啶-4,6-二胺 | CAS号2164-84-3 5-硝基-4,6-二氨基嘧啶 | CAS号54288-02-7 5-phenylazopyri... | CAS号103261-00-3 5-(4-chloro-phe... | CAS号1073-99-0 2-巯基-4,5,6-三氨基嘧啶 | CAS号29767-70-2 9-(1-ethoxyethy... | CAS号2829-57-4 [1,2,5]thiadiaz... | CAS号1123-54-2 8-氮杂腺嘌呤 | CAS号31992-21-9 7(1H)-Pteridino... | CAS号21149-26-8 8-羟基腺嘌呤 | CAS号6973-01-9 4-Pteridinamine | CAS号73384-11-9 7-phenylpteridi... | CAS号6306-88-3 [1,2,5]Thiadiaz... | CAS号5122-36-1 4,6-二氨基-5-(甲酰氨基)嘧啶

📜4,5,6-三氨基嘧啶硫酸盐置于sodium Hydroxide体系中,用 水 用作溶剂,以3.69 G的收率获得4,5,6-三氨基嘧啶
参考文献:碳11标记的咪唑并吡啶-和嘌呤-硫代乙酰胺衍生物的合成,作为新型潜在的pet示踪剂,用于核苷酸焦磷酸酶/磷酸二酯酶1(npp1)的成像
标题:碳11标记的咪唑并吡啶-和嘌呤-硫代乙酰胺衍生物的合成,作为新型潜在的pet示踪剂,用于核苷酸焦磷酸酶/磷酸二酯酶1(npp1)的成像
摘要:目标示踪剂碳11标记的咪唑并吡啶和嘌呤硫代乙酰胺衍生物n-(3-[ 11 C]甲氧基-4-甲氧基苯基)-2-((5-甲氧基-3 H-咪唑并[4,5-B ] Pyridin-2-Yl)thio)acetamide(3-[ 11 C] 4A)和n-(4-[ 11 C]甲氧基-3-甲氧基苯基)-2-((5-5-甲氧基-3 H-咪唑[4,5-B ]吡啶-2-基)硫基)乙酰胺(4-[ 11 C]图4A); 2-((6-氨基-9 H-嘌呤-8-基)硫基)-N-(3-[ 11 C]甲氧基-4-甲氧基苯基)乙酰胺(3-[ 11 C] 8A)和2-((6-氨基-9 H-嘌呤-8-基)硫基)-N-(4-[ 11 C]甲氧基-3-甲氧基苯基)乙酰胺(4-[ 11 C] 8A).通过在碱性条件下(2 N Naoh)用[ 11 C] Ch 3 Otf对相应的前体进行o-[ 11 C]甲基化,
Doi:10.1016/j.Bmcl.2016.01.081

专利信息

专利号:US-7105666-B2
优先权日:2002-06-27
标 题:Synthesis of purine derivatives
发明人：HAMMARSTROEM LARS G J; KRAUSS NANCY ELISABTH; LABADIE SHARADA SHENVI; SMITH DAVID BERNARD; TALAMAS FRANCISCO XAVIER
权利人:ROCHE PALO ALTO LLC
摘要:The present invention provides a method for producing 2-, 6-, 8- and 9-substituted purine compounds from 4,6-dihalo-5-nitro-2-alkyl-pyrimidine compounds in solution or by solid phase techniques. The present process provides for the sequential introduction of amine substituents at the 4- and 6-positions, displacement of an alkylsulfony group at the 2-position of the pyrimidine, reduction of the nitro group and formation of the imidazole portion of the purine compound. Furthermore, the methods of the present invention are ideally suited to the preparation of a library of purine compounds.

专利号:US-2012184724-A1
优先权日:2009-09-22
标 题 :Protected monomers and methods of deprotection for rna synthesis
发明人：SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN
权利人:SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN; AGILENT TECHNOLOGIES INC
摘要:A nucleoside monomer that is protected by a thionocarbamate protecting group and contains one or more 2 H, 13 C, or 15 N isotopes in the ribose and/or base part is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.

专利号:US-9943809-B2
优先权日:2014-02-27
标题 :Solvent resistant thin film composite membrane and its preparation
发明人：DOM ELKE; HERMANS SANNE; KOECKELBERGHS GUY; VANKELECOM IVO
权利人:KATHOLIEKE UNIV LEUVEN KU LEUVEN RESEARCH & DEVELOPMENT; UNIV LEUVEN KATH
摘要:The present invention relates to improved methods for synthesis of thin film composite membranes by interfacial polymerization. More in particular, the method of the present invention comprises the impregnation of an ultrafiltration porous support membrane with an aqueous solution containing a polyfunctional nucleophilic monomer, and contacting the impregnated support membrane with a second largely water-immiscible solvent containing a polyfunctional epoxide monomer.

专利号:CA-2488562-A1
优先权日:2002-06-27
标 题:Synthesis of purine derivatives

专利号:EP-1112281-B1
优先权日:1998-09-08
标 题:Pteridine nucleotide analogs
发明人：HAWKINS MARY E; PFLEIDERER WOLFGANG; BALIS FRANK
权利人:US GOV HEALTH & HUMAN SERV
摘要:The invention provides pteridine nucleotides of formula (I) which are highly fluorescent and which can be used in the chemical synthesis of fluorescent oligonucleotide. The invention further provides for fluorescent oligonucleotide comprising one or more pteridine nucleotides. In addition the invention provides for pteridine nucleotide triphosphates which may be used as the constituent monomers in DNA amplification procedures. The pteridine nucleotides are more stable and possess higher quantum yields than structurally similar pteridine nucleotides.

专利号:JP-2005535631-A
优先权日:2002-06-27
标题 :Synthesis of purine derivatives