CAS: 1150114-80-9; 1-Methyl-1H-Indazole-6-Boronic Acid
该化合物是B-(1-甲基1-H-indazol-6-yl)-,是一种有机体化合物,其特点是附于1-甲基-1H-indazol efity的有机酸性功能组(-B(OH)2),该化合物通常具有白色至非白色固体等特性,由于存在乙酸组,在水和酒精等极溶剂中溶解性. 博鲁尼酸因其与二醇形成可逆共价结合的能力而闻名,使其在各种应用中,包括在有机合成和药用化学等应用中具有价值.它们可以作为刘易斯酸,经常用于铃木的混合反应,这对于合成复杂的有机分子形成碳-碳联系十分重要. 此外,由于丁诺尔环有助于化合物的潜在生物活动,因此引起对制药研究的兴趣.
相似化合物
1256359-09-7 1001907-57-8 1001907-60-3物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
急性毒性 类别4(吸入)
急性毒性 类别4(经皮)
急性毒性 类别4(经口) - 警示词Warning(警告)
- 危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H332 |吸入有害.
H312 |皮肤接触有害.
H302 |吞咽有害. - 防范说明P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
- UN编号NONH for all modes of transport
- 危险品标志Xi
- 安全声明26
- 危险类别码36/37/38
- WGK Germany3
欧盟法规
C&L通报合成工艺路线路线简述
海关参考信息
- 2902200000-苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10995078-B2
优先权日:2013-03-13
标 题:Compounds and compositions for inhibition of FASN
发明人：BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
权利人:FORMA THERAPEUTICS INC
摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
专利号:US-9051289-B2
优先权日:2013-09-26
标 题 :Process and intermediates for preparing GPR40 agonists
发明人：DAHMANN GEORG; WAGNER HOLGER; ECKHARDT MATTHIAS; FRANK MARKUS; SANTAGOSTINO MARCO; SCHNAUBELT JUERGEN; STERTZ UWE; PACHUR THORSTEN
权利人:DAHMANN GEORG; WAGNER HOLGER; ECKHARDT MATTHIAS; FRANK MARKUS; SANTAGOSTINO MARCO; SCHNAUBELT JUERGEN; STERTZ UWE; PACHUR THORSTEN; BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of formula I n nwherein R S denotes F or CF 3 , R a denotes H or C 1-4 -alkyl and Z denotes a leaving group or an optionally substituted or protected hydroxyl group, suitable as intermediates in the synthesis of indanyloxydihydrobenzofuranylacetic acids, which are GPR40 agonists, to a process for preparing these intermediates and to the process for preparing the GPR40 agonists making use of an asymmetric catalytic hydrogenation reaction in the presence of a transition metal catalyst and a chiral auxiliary.
专利号:US-9308194-B2
优先权日:2013-11-28
标 题:Indanyloxyphenylcyclopropanecarboxylic acids
发明人：LINGARD IAIN; HAMPRECHT DIETER
权利人:BOEHRINGER INGELHEIM INT
摘要:A compound of formula I, n nwherein the groups R 1 , R 2 , R 3 , X, m, and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
