CAS: 334618-23-4; (R)-Piperidin-3-Amine Dihydrochloride

相似化合物

127294-73-9 138060-07-8 168466-84-0

上下游产品

pyridin-3-ylamine N-acetyl-3-aminopyridine acetate N-acetyl-3-aminopiperidine acetate nipecotamide (S)-3-(2,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)propanoic acid (S)-3-aminopiperidine salt

(R)-Piperidine-3-Amine Dibenzoyl-D-Tartrate,水,盐酸置于异丙醇体系中,用 异丙醇 用作溶剂,化学反应 22.5H,以to Get 26oc.的收率获得(R)-(-)-3-氨基哌啶 二盐酸盐
参考文献:Process For Preparation Of Pure Linagliptin
标题:Process For Preparation Of Pure Linagliptin
摘要:本申请提供了一种制备林那格列汀的方法,该方法是在惰性有机溶剂中,在适当的碱的存在下,将ii式的(R)-哌啶-3-胺或其酸加成盐与iii式的1-[(4-甲基-喹唑啉-2-基)甲基]-3-甲基-7-(2-丁炔-1-基)-8-溴黄嘌呤反应.

专利信息

专利号:US-11401269-B2
优先权日:2018-05-15
标 题 :Intermediates and processes for the preparation of Linagliptin and its salts
发明人：CIANCIMINO CRISTINA; TRAGNI MICHELE; VIGO DANIELE; PICCOLO ORESTE
权利人:CAMBREX PROFARMACO MILANO S R L
摘要:Disclosed are new intermediates for the synthesis of Linagliptin and of its salts and a process for its preparation involving said intermediates.

专利号:CN-110724675-A
优先权日:2019-10-31
标题:Transaminase catalyst and method for enzymatic synthesis of (R)-1-tert-butoxycarbonyl-3-aminopiperidine

专利号:CN-104387315-A
优先权日:2013-11-12
标 题:Compound I and (R)-3-aminopiperidine hydrochloride II, its preparation method and its application in the synthesis of linagliptin

专利号:CN-104387315-B
优先权日:2013-11-12
标 题 :Compound I and (R)-3-aminopiperidine hydrochloride II, its preparation method and its application in the synthesis of linagliptin

专利号:CN-110724675-B
优先权日:2019-10-31
标题 :Transaminase catalyst and method for enzymatic synthesis of (R)-1-tert-butoxycarbonyl-3-aminopiperidine

专利号:CN-113121414-B
优先权日:2020-01-15
标题 :A kind of synthesis method of trolagliptin intermediate