CAS: 2438-10-0; (S)-1-Isopropyl-4-Methylcyclohex-3-Enol

该化合物是天然地出现在茶树油等基本油类中的一种单分子酒精,具有显著的抗微生物,抗炎和抗硫特性,在药品和化妆品应用中具有价值.作为(+)-抗生素,该化合物的手性纯度确保了制剂的连续生物活动和功效.有机溶剂中的溶解性和中度挥发性有助于将其纳入局部制剂和消毒剂中. (+)-Terpinen-4-ol还研究其潜在的治疗作用,包括创伤愈合和丙烷治疗.具有明确的安全特征,它是皮肤和抗微生物制品中的一种首选成分.

结构式图片

相似化合物

20126-76-5 562-74-3 515-69-5

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CAS号7785-70-8 蒎烯 | CAS号498-81-7 氢化松油醇

合成工艺路线路线简述

    📜(+)-α-蒎烯 反应生成(+)-4-萜品醇
    参考文献:Reisman,Bulletin De La Societe Chimique De France,1927,Vol. <4> 41,P. 97
    标题:Reisman,Bulletin De La Societe Chimique De France,1927,Vol. <4> 41,P. 97

    海关参考信息

    专利信息


    专利号:US-2005003188-A1
    优先权日:2003-03-21
    标题 :Thermolytic synthesis of inorganic oxides imprinted with functional moieties
    发明人:BASS JOHN D; KATZ ALEXANDER
    权利人:UNIV CALIFORNIA
    摘要:Inorganic oxides, particularly silica or germania or inorganic oxides containing silica and/or germania, are imprinted with one or a plurality of functional moieties such as amine and/or thiol groups by a process featuring incorporating such groups into the oxide by use of a thermally labile material containing a protecting group for the amine or thiol, followed by removal of the thermally labile moiety by thermolysis. The resulting products are inorganic oxide substrates or bulk inorganic oxides imprinted with the functional moieties. A plurality of such moieties may be imprinted on a substrate in an order fashion using a polymeric imprinting compound, and may then be used as a templated array of functional moieties to which ordered metallic nanostructures may be constructed.

    专利号:US-2004053999-A1
    优先权日:1997-09-17
    标题 :Novel compounds and methods for synthesis and therapy
    发明人:BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
    摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

    专利号:US-6225341-B1
    优先权日:1995-02-27
    标 题:Compounds and methods for synthesis and therapy
    发明人:BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
    权利人:GILEAD SCIENCES INC
    摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

    专利号:US-5879690-A
    优先权日:1995-09-07
    标题:Topical administration of catecholamines and related compounds to subcutaneous muscle tissue using percutaneous penetration enhancers
    发明人:PERRICONE NICHOLAS V
    摘要:Compositions for the topical treatment of sagging subcutaneous muscle and overlying cutaneous tissue contain an active ingredient exhibiting or producing catecholamine activity such as catecholamines and/or related compounds in a dermatologically acceptable carrier that contains at least one percutaneous penetration enhancer. Examplary catecholamines include adrenaline, norepinepherine, dopamine and their precursors; catecholamine precursors such as tyrosine and phenylalanine are preferred. Many embodiments, particularly those employing tyrosine and/or phenylalanine as a catecholamine precursor, further contain a neurotransmitter synthesis enhancer such as dimethylaminoethanol, and other co-factors such as vitamin B 6 and pantothenic acid or calcium pantothenate are included in the composition to enhance the action of the active ingredients. Other compounds that scavenge free radicals and antioxidants may also be added.

    专利号:US-11596930-B2
    优先权日:2020-04-08
    标 题 :Nickel/titanium oxide-silicon oxide catalyst for synthesizing terpinene-4-ol, preparation method thereof, and method of synthesizing terpinene-4-ol using the same
    发明人:ZHENG HUIDONG; WU DAN; CHEN JINGJING; LIU JIE; WU NAIXIN
    权利人:UNIV FUZHOU
    摘要:The present invention discloses a nickel/titanium oxide-silicon oxide catalyst for synthesizing terpinene-4-ol as well as a preparation method and method of synthesizing terpinene-4-ol using the same. The preparation method includes the steps of catalyst preparation, terpinene-4-ol synthesis and the like are disclosed in the present invention. The preparation method includes the following steps: firstly, preparing a mixed colloid of TiO2 and SiO2 by using a sol-gel method, and then centrifuging, washing, drying and roasting is performed to prepare a TiO2—SiO2 binary oxide; then, preparing Ni/TiO2-SiO2 by dipping in a nickel nitrate solution, and preparing a supported catalyst by drying and roasting; and finally, adopting a terpinolene-4, 8-epoxide a raw material, carrying out isomerization under the dual catalytic action of TiO2-SiO2 and Ni of the supported catalyst, and carrying out hydrogenation to prepare terpinene-4-ol. The preparation method can combine isomerization and hydrogenation reaction on the same catalyst, has good selectivity on terpinene-4-ol, and is simple to operate and high in product yield.

    专利号:WO-9632368-A1
    优先权日:1995-04-11
    标题:One-pot synthesis of ring-brominated benzoate compounds

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Christian Zorzetto, Et Al. Phytochemical Analysis And In Vitro Biological Activity Of Three Hypericum Species From The Canary Islands (Hypericum Reflexum, Hypericum Canariense And Hypericum Grandifolium). Fitoterapia. 2015 Jan:100:95-109.
    [参考文献]: Raimunda Samia Nogueira Brilhante, Et Al. In Vitro Inhibitory Activity Of Terpenic Derivatives Against Clinical And Environmental Strains Of The Sporothrix Schenkii Complex. Med Mycol. 2015 Feb 1;53(2):93-8.
    [参考文献]: Seon-Mi Seo, Et Al. Fumigant Toxicity And Acetylcholinesterase Inhibitory Activity Of 4 Asteraceae Plant Essential Oils And Their Constituents Against Japanese Termite (Reticulitermes Speratus Kolbe). Pestic Biochem Physiol. 2014 Jul:113:55-61.
    [参考文献]: Yi Lan, Et Al. Essential Oil From Zanthoxylum Bungeanum Maxim. And Its Main Components Used As Transdermal Penetration Enhancers: A Comparative Study. J Zhejiang Univ Sci B. 2014 Nov;15(11):940-52.

    合成参考文献


    摘要:S55 | ZINC15PHARMA | Pharmaceuticals from ZINC15 | DOI:10.5281/zenodo.3247749
    摘要:The Good Scents Company Information System
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