CAS: 22224-41-5; 1,3,5-Tri-O-Benzoyl-A-D-Ribofuranose

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1-O-Methyl-2,3,5-Tri-O-Benzoyl-D-Ribofuranose置于水,氢溴酸体系中,用 二氯甲烷 用作溶剂,化学反应 1.0H,反应生成1,3,5-三苯甲酰基-D-呋喃核糖
参考文献:A Stereocontrolled Synthesis Of 1,3,5-Tri-O-Benzoyl-.Alpha.-D-Ribofuranose
标题:A Stereocontrolled Synthesis Of 1,3,5-Tri-O-Benzoyl-.Alpha.-D-Ribofuranose
摘要:
Doi:10.1021/jo00214A045

专利信息

专利号:EP-1108724-B1
优先权日:1996-01-16
标题 :Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules
发明人：WINCOTT FRANCINE; BEIGELMANN LEONID; MATULIC-ADAMIC JASENKA; USMAN NASSIM; HAEBERLI PETER; KARPEISKY ALEXANDER; SWEEDLER DAVID; JARVIS THALE; DIRENZO ANTHONY
权利人:SIRNA THERAPEUTICS INC
摘要:This invention relates to chemical synthesis of 2'-O-methyl, 3'-O-methyl and 5'-O-methyl nucleosides, incorporation of novel chemical modifications in enzymatic nucleic acid molecules and improved methods for the synthesis of enzymatic nucleic acid molecules.

专利号:US-6972330-B2
优先权日:1996-02-13
标题:Chemical synthesis of methoxy nucleosides
发明人：BEIGELMAN LEONID; HAEBERLI PETER; KARPEISKY ALEXANDER; SWEEDLER DAVID
权利人:SIRNA THERAPEUTICS INC
摘要:Process for chemical synthesis of methoxy nucleosides.

专利号:US-6462191-B1
优先权日:2000-07-13
标 题 :Synthesis of 2-deoxy-2-fluoro-arabinose derivatives
发明人：LAL GAURI SANKAR
权利人:AIR PROD & CHEM
摘要:A process for deoxofluorinating a C2-hydroxyl group of a furanose, includes: (a) mixing the furanose and a deoxofluorinating agent in a solvent to form a reaction mixture, and (b) heating the reaction mixture to greater than about 50° C. The process provides deoxofluorinated products, such as 2-fluoro-arabinoses, in yields of at least 80% of theoretical.

专利号:US-5962675-A
优先权日:1996-02-13
标 题:Chemical syntheses of 2'-O-methoxy purine nucleosides
发明人：BEIGELMAN LEONID; SWEEDLER DAVID; HAEBERLI PETER; KARPEISKY ALEXANDER
权利人:RIBOZYME PHARM INC
摘要:Several processes for the chemical synthesis of 2'-O-methoxy purine nucleosides are herein disclosed.

专利号:US-6891036-B2
优先权日:2003-02-10
标题:Process for the preparation of ribofuranose derivatives
发明人：TAMERLANI GIANCARLO; SALSINI LIANA; LOMBARDI ILARIA; BARTALUCCI DEBORA; CIPOLLETTI GIOVANNI
权利人:INALCO SPA
摘要:The present invention relates to a new process in 3 steps starting from 2-C-methyl-D-ribopentono-1,4-lactone for the preparation of tetra-acyl ribofuranose derivatives of formula (I): n n nuseful in the synthesis of nucleotides.

专利号:EP-1600451-A2
优先权日:1999-11-12
标题 :Synthesis of 2'-deoxy-l-nucleosides