CAS: 13028-69-8; N,N,N-Triethylbutan-1-Aminium Bromide

相似化合物

1643-19-2 1643-19-2 866-97-7

上下游产品

ethyl bromide N,N-diethylbutylamine 1-bromo-butane triethylamine N,N-diethylbutylamine triethylamine triethyl N-butyl ammonium hydroxide

📜正溴丁烷,三乙胺 以 乙醇 用作溶剂,化学反应生成(1-丁基)三乙基溴化铵
参考文献:胆碱能阴离子受体iii
标题:胆碱能阴离子受体iii
摘要:为了识别胆碱能阴离子受体的某些非常好特性,最初的研究是对乙酰胆碱酯酶抑制剂的研究,该抑制剂使用的是相对无构象变化的抑制剂.所用的抑制剂是季铵化的1-氮杂双环(2.2.2)辛烷.双环母体胺通过几种常规方法制备.通过滴定法将这些盐评价为乙酰胆碱酯酶的竞争性抑制剂.将这些化合物对该酶的阴离子位点的亲和力与一系列发生构象变化的相关盐的亲和力进行了比较.这些比较表明,该胆碱能受体的阴离子位点比迄今所怀疑的更具有立体化学要求.
Doi:10.1002/jps.2600550413

专利信息

专利号:US-7576234-B2
优先权日:2002-05-15
标题 :Synthesis of 2-alkyl amino acids
发明人：CHORGHADE MUKUND S; GURJAR MUKUND K; MOHAPATRA DEBENDRA K
权利人:GENZYME CORP
摘要:Non-natural amino acids such as 2-alkylated amino acids allow for the synthesis of a wider variety of peptidal and non-peptidal pharmaceutically active agents. A method of preparing a 2-alkyl amino acid involves a Michael-type addition of a nucleophile to a dialkyl 2-methylidenylpropan-1,3-dioate and the conversion of a ester moiety into an amino moiety. The present invention also discloses a method of preparing a class of iron chelating agents related to desferrithiocin, all of which contain a thiazoline ring. In this method, an aryl nitrile or imidate is condensed with cysteine, a 2-alkyl cysteine, or a cysteine ester.

专利号:US-2017349757-A1
优先权日:2014-12-23
标 题:Continuous flow process for manufacturing surface modified metal oxide nanoparticles by supercritical solvothermal synthesis
发明人：THEODET MANUEL; AYMONIER CYRIL
权利人:ESSILOR INT (COMPAGNIE GENERAL D'OPTIQUE); NIPPON KOGAKU KK; CENTRE NATIONAL DE LA RECHERCHE SCIENT - CNRS
摘要:The invention concerns a continuous flow process for manufacturing surface modified metal oxide nanoparticles by supercritical solvothermal synthesis in an reaction medium flowing within a continuous flow chamber, said continuous flow chamber containing a hydrolysis area and a supercritical area, said process comprising the introduction of a flow of metal oxide precursor into the continuous flow chamber at a point P located in the hydrolysis area or in the supercritical area, and the introduction of a flow of is located downstream of P 1 with respect to the flow direction, as well as the device for carrying out this process.

专利号:US-2003236435-A1
优先权日:2002-05-15
标题 :Synthesis of 2-alkylcysteine via substituted thiazoline ester

专利号:EP-3567040-B1
优先权日:2013-06-24
标 题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines

专利号:US-2004082796-A1
优先权日:2002-05-15
标 题 :Synthesis of substituted thiazoline carboxylic acids

专利号:US-8809585-B2
优先权日:2004-10-02
标 题:Synthesis scheme for lacosamide
发明人：RIEDNER JENS; DUNNE GAVIN
权利人:RIEDNER JENS; DUNNE GAVIN; UCB PHARMA GMBH
摘要:The present invention is concerned with an improved method of producing (R)-2-acetamido-N-benzyl-3-methoxypropionamide (lacosamide) comprising the 0-methylation of a compound of formula (I) to produce a compound of formula (II) in a single step reaction.