📜Dmapp,(S)-柚皮素置于fungal Prenyltransferase Anapt,Calcium Chloride体系中,用 二甲基亚砜,甘油 用作溶剂,化学反应 16.0H,以54.2%的收率获得3'-异戊烯基柚皮素
参考文献:Complementary Flavonoid Prenylations By Fungal Indole Prenyltransferases
标题:Complementary Flavonoid Prenylations By Fungal Indole Prenyltransferases
摘要:Flavonoids Are Found Mainly In Plants And Exhibit Diverse Biological And Pharmacological Activities,Which Can Often Be Enhanced By Prenylations. In Plants,Such Reactions Are Catalyzed By Membrane-Bound Prenyltransferases. In This Study,The Prenylation Of Nine Flavonoids From Different Classes By A Soluble Fungal Prenyltransferase (Anapt) Involved In The Biosynthesis Of The Prenylated Indole Alkaloid Acetylaszonalenin Is Demonstrated. The Behavior Of Anapt Toward Flavonoids Regarding Substrate Acceptance And Prenylation Positions Clearly Differs From That Of The Indole Prenyltransferase 7-Dmats. The Two Enzymes Are Therefore Complementary In Flavonoid Prenylations.
Doi:10.1021/acs.Jnatprod.5B00422