专利号:US-2024229131-A1 优先权日:2022-12-22 标 题 :Transition-metal catalyst compositions and methods for sequencing by synthesis 发明人:MARIANI ANGELICA; BEECH TIMOTHY; FRANCAIS ANTOINE; PANIGRAHI ADYASHA; HATTINGH KATHRYN; CRESSINA ELENA 权利人:ILLUMINA INC 摘要:The present application relates to compositions and methods for sequencing by synthesis. A blocking group of a nucleotide may be removed by a transition metal catalyst, the transition metal catalyst activated by a non-reducing ligand and a reducing agent.
专利号:US-11305268-B2 优先权日:2011-08-18 标 题:Hydrogenation and dehydrogenation catalyst, and methods of making and using the same 发明人:GOUSSEV DMITRI; SPASYUK DENIS 权利人:GOUSSEV DMITRI; SPASYUK DENIS 摘要:The present application discloses complexes useful as catalysts for organic chemical synthesis including hydrogenation and dehydrogenation of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for variety of chemicals.
参考文献:10.1007/978-3-642-31081-2_9 摘要:St. John A, Goldberg KI, Heinekey DM. Pincer Complexes as Catalysts for Amine Borane Dehydrogenation. 2013. In: Organometallic Pincer Chemistry. : Springer Berlin Heidelberg; 2013.