CAS: 99749-54-9; A-D-Mannose-1-Phosphate (Sodium)
该化合物是一种广泛用于生物化学和藻类生物学研究的磷酸甲酸盐衍生物,该化合物是含有单氧酸盐的凝聚途径和酶合成的关键中间体,其高纯度和稳定性使其适合于对碳水化合物新陈代谢,玻璃凝聚生物合成物和酶动能学的研究.钠形式可增强水溶液的溶性,促进其在体外试验和代谢研究中的使用.研究人员认为该化合物在对甘醇转移酶和磷酸盐活动进行预测的作用及其在对碳水酸酯活性酶的结构和功能调查中的效用.该化合物通常用于需要定义明确的糖磷酸亚酸盐的受控反应系统.
- 英文名称A-D-Mannose-1-Phosphate (Sodium)
- 中文名称aD-甘露糖-1-磷酸(钠)
- IUPAC名称sodium (2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl phosphate
- 其它别名α-D(+)Mannose 1-Phosphate Sodium Salt Hydrate; α-D-Mannopyranosyl Phosphate
- CAS编号99749-54-9
- MFCD编号:MFCD00069783
- FDA UNII编号:HPI5FB7OGU
- 分子式:C6H11Na2O9P分子量:304.1
- 产品CID: 2032552
- 产品分类有机原料→分子砌块→手性化合物→手性砌块
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上下游产品
D-glucose pentaacetate 2,3,4,5-tetra-O-acetyl-D-glucopyranose dibenzyl 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl phosphite dibenzyl 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl phosphate合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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专利信息
专利号:US-2007178487-A1
优先权日:2000-12-13
标题:Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and 'unnatural' udp- and tdp-nucleotide sugars
专利号:US-2003055235-A1
优先权日:2000-12-13
标 题 :Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and 'unnatural' UDP- and TDP-nucleotide sugars
专利号:WO-0248331-A2
优先权日:2000-12-13
标 题 :Active-site engineering of nucleotidyltransferases and enzymatic methods for the synthesis of natural and 'unnatural' udp- and nucleotide sugars
专利号:US-7122359-B2
优先权日:2000-12-13
标题 :Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and “unnaturalâ€? UDP- and TDP-nucleotide sugars
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主要参考文献
1: Enotarpi J, Tontini M, Balocchi C, van der Es D, Auberger L, Balducci E, Carboni F, Proietti D, Casini D, Filippov DV, Overkleeft HS, van der Marel GA, Colombo C, Romano MR, Berti F, Costantino P, Codeé JDC, Lay L, Adamo R. A stabilized glycomimetic conjugate vaccine inducing protective antibodies against Neisseria meningitidis serogroup A. Nat Commun. 2020 Sep 7;11(1):4434. doi: 10.1038/s41467-020-18279-x. Erratum in: Nat Commun. 2020 Nov 25;11(1):6155.
2: Lamosa P, Lourenço EC, d'Avó F, Nobre A, Bandeiras TM, da Costa MS, Ventura MR, Santos H. A unique glyceryl diglycoside identified in the thermophilic, radiation-resistant bacterium Rubrobacter xylanophilus. Extremophiles. 2015 Mar;19(2):373-82. doi: 10.1007/s00792-014-0723-0. Epub 2015 Jan 3. 8(11):2561-7. doi: 10.1021/cb400463u. Epub 2013 Sep 19. 10(33):6673-81. doi: 10.1039/c2ob25222h.
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