CAS: 821-10-3; 1,4-Dichlorobut-2-Yne

上下游产品

CAS号110-65-6 2-丁炔-1,4-二醇 | CAS号16669-40-2 but-2-yne-1,4-b... | CAS号110-86-1 吡啶 | CAS号7719-09-7 氧氯化硫 | CAS号7647-01-0 盐酸 | CAS号64-19-7 冰醋酸 | CAS号10026-13-8 五氯化磷 | CAS号71-43-2 苯 | CAS号111339-46-9 N-[2-[4-(2-acet... | CAS号111-53-5 1,4-双(二甲基氨基)-2-丁炔 | CAS号105-18-0 2-Butyne-1,4-di... | CAS号3757-53-7 5-甲基-1H-吡咯-2-甲酸 | CAS号3284-51-3 5-甲基-1H-吡咯-2-甲酸乙酯 | CAS号14272-28-7 2-Butyne,1,4-bi... | CAS号14304-31-5 hept-1-en-4,6-d... | CAS号4819-69-6 N-(4-氯－2－丁基)邻苯二甲酰亚胺 | CAS号928-49-4 3-己炔 | CAS号513-81-5 2,3-二甲基-1,3-丁二烯

But-2-Ynyl-Bisoxycarbonyl Chloride置于n,N-二甲基甲酰胺体系中,用 1,2-二氯乙烷 作为反应溶剂,以76%的收率获得产物1,4-二氯-2-丁炔
参考文献:Dimethylformamide-Catalyzed Decarboxylation Of Alkyl Chloroformates. A Synthesis Of Primary Alkyl Chlorides
标题:Dimethylformamide-Catalyzed Decarboxylation Of Alkyl Chloroformates. A Synthesis Of Primary Alkyl Chlorides
摘要:
DOI:10.1021/jo00163A047

专利信息

专利号:US-6252079-B1
优先权日:1993-06-30
标 题 :Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; BOM DAVID
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of irinotecan and derivative compounds which comprises of a novel 4+1 radical annulation wherein the precursoris reacted with an aryl isonitrile having the formulawherein X is Br or I, and R4 is an alkyl group, an allyl group, a propargyl group or a benzyl group, and R16 is H, a C1-C6 alkoxy group, agroup wherein p is an integer between 4 and 12, or a C1-C12 acyclic dialkylamino group. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-6982333-B2
优先权日:1993-06-30
标 题:Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; JOSIEN HUBERT; KO SUNG BO
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of camptothecin and related compounds which consists of a novel 4+1 radical annulation. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-4623703-A
优先权日:1984-10-24
标题 :Synthesis of conducting polymers: polybutadienes from disubstituted butynes
发明人：THYAGARAJAN BUDALUR S
权利人:UNIV TEXAS
摘要:A two-step method is disclosed for chemically synthesizing substituted butadiene polymers from 1,4-disubstituted butynes. The first step in the synthesis of the butadiene polymer is the polymerization of 1,4-disubstituted butyne monomers. The substituted butyne polymer which results is then isomerized to the corresponding substituted butadiene polymer by subjecting the butyne to a weak organic base such as triethylamine. The isomerization reaction can be performed under very mild conditions and proceeds at ambient temperature.

专利号:WO-2024112764-A1
优先权日:2022-11-21
标 题:Synthesis of pyrrolo[3,4-c]pyrroles
发明人：LUKE GEORGE P; RODRIGUEZ SONIA; OUELLET STEPHANE G; GORINS GILLES; DIKER KHALID; BEAUDENON AURÉLIE; COUSIN JONATHAN
权利人:NOVO NORDISK HEALTHCARE AG
摘要:Novel synthetic methods of making pyrrolo[3,4- c ]pyrroles, derivatives thereof, and intermediates thereto are provided. Also provided are methods using pyrrolo[3,4- c ]pyrroles in the processes for preparing bioactive compounds ( e.g. PKR Activating Compounds).

专利号:US-4505792-A
优先权日:1981-03-03
标题:Photochemical rearrangement of 2-aminopyrrolin-5-ones to aminocyclopropyl isocyanates and polymers thereof
发明人：KOCH TAD H; SWANSON BARRY J
权利人:UNIVERSITY PATENTS INC
摘要:Subjecting 1,4-bis-[(pyrrolin-3-onyl)methylamino]-2-butyne to ultraviolet irradiation effects rearrangement in greater than 80% yield to 1,4-bis-[(isocyanatocyclopropyl)methylamino]-2-butyne. The diisocyanate is useful in the synthesis of polyurethanes and polyureas and also for the in situ photochemical generation of a cross-linking agent for polyurethanes and structurally related polymers.

专利号:US-2004063947-A1
优先权日:1993-06-30
标 题:Novel intermediates in the synthesis of camptothecin and related compounds and synthesis thereof