丙烷置于二氯甲烷,五氟化锑体系中,用69%的收率获得产物2-氯丙烷 参考文献:Synthetic Methods And Reactions. 137. Ionic Chlorination (Bromination) Of Alkanes And Cycloalkanes With Methylene Chloride (Bromide)/antimony Pentafluoride 标题:Synthetic Methods And Reactions. 137. Ionic Chlorination (Bromination) Of Alkanes And Cycloalkanes With Methylene Chloride (Bromide)/antimony Pentafluoride 摘要: DOI:10.1021/jo00267A047
专利号:US-2024309024-A1 优先权日:2023-03-14 标题 :Direct synthesis of alkenylhalosilanes 发明人:LEWIS KENRICK MARTIN; ZHU YANJUN; BYRNE CHRISTOPHER M 权利人:MOMENTIVE PERFORMANCE MAT INC 摘要:A process for the direct synthesis of alkenylhalosilane monomers. Forming a slurry of liquid and copper-activated silicon from fresh silicon, cyclone fines and/or fine dust from silicon grinding, ultrafines and/or spent contact mass from the Direct Synthesis of alkylhalosilanes and arylhalosilanes, in a thermally stable solvent. Reacting the silanes by agitating the slurry with at least one unsaturated aliphatic or cycloaliphatic organohalide of the formula R1X, and optionally an organohalosilane and/or hydrogen halide, in the presence of a polymerization inhibiting Lewis base additive, at a reaction time, temperature and pressure effective to produce alkenylhalosilanes having the formulae, R1SiHX2, R12SiHX, R13SiX, R1SiX3, and R12SiX2 or mixtures thereof.
专利号:US-2021107859-A1 优先权日:2018-04-06 标题 :A process for the synthesis of carbon labeled organic compounds 发明人:AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA 权利人:COMMISSARIAT ENERGIE ATOMIQUE 摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.
专利号:US-9126995-B2 优先权日:2011-11-08 标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound 发明人:TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU 权利人:NISSAN CHEMICAL IND LTD 摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.
专利号:US-7173059-B2 优先权日:2003-05-08 标题:Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same 发明人:ALBIZATI KIM FRANCIS; BABU SRINIVASAN 权利人:AGOURON PHARMA 摘要:Optically active 3-amino-butene and 1,2-dihydroxy-3-amino-butane intermediate compounds, useful in the synthesis of HIV-protease inhibitors and methods of preparing these intermediate compounds are disclosed.
专利号:US-11306041-B2 优先权日:2017-03-30 标 题:Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts 发明人:SCHINSKI WILLIAM; GOLDMAN ALAN; GUNNOE THOMAS B; WEBSTER-GARDINER MICHAEL S; SCHWARTZ NICHOLE 权利人:UNIV VIRGINIA PATENT FOUNDATION 摘要:Catalytic methods for synthesis of super linear alkenyl arenes and alkyl arenes are provided. The methods are capable of synthesizing super linear alkyl and alkenyl arenes from simple arene and olefin starting materials and with high selectivity for linear coupling. Methods are also provided for making a 2,6-dimethylnapthalene (DMN) or 2,6-methylethylnapthalene (MEN).
专利号:US-4581416-A 优先权日:1981-01-19 标题 :Process for the synthesis of tertiary phosphine oxides and sulfides, and new tertiary phosphine oxides and sulfides 发明人:BERGERET WILFRID; BOILEAU SYLVIE; GAUTIER JEAN-CLAUDE; RAYNAL SERGE 权利人:POUDRES & EXPLOSIFS STE NALE 摘要:The invention relates to processes for the synthesis of tertiary phosphine oxides and sulfides. The process according to the invention consists, in a first step, of reacting a secondary phosphine oxide or sulfide with an optionally activated alkali metal amide, and, in a second step, of reacting the mixture obtained in the first step with an organic halide containing at least one halogenophenyl radical or one halogenomethyl group. Tertiary phosphine oxides and sulfides are complexing agents of high stability.
摘要:Aitken, R. A.; Aitken, K. M., Science of Synthesis, (2010) 47, 1051. 摘要:Inoue, S.; Driess, M., Science of Synthesis Knowledge Updates, (2012) 4, 234. 摘要:Gigiena i Sanitariya. For English translation, see HYSAAV., 55(7)(93), 1990 摘要:Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA10 8 摘要:Weast, R.C. and M.J. Astle. CRC Handbook of Data on Organic Compounds. Volumes I and II. Boca Raton, FL: CRC Press Inc. 1985., p. V2 180