CAS: 591-60-6; Butyl 3-Oxobutanoate

该化合物是乙酸的酯衍生物,这种明显,无色液体的特点是有水果味和中度波动,是有机合成的多种中间体,特别是在生产药品,农用化学品和香味方面.它的活性β-基至酯结构能够参与凝聚反应,如Knoevenagel和Michael添加,因此对构建复杂的分子框架很有价值.化合物展示了普通有机溶剂的溶解性良好,促进了其在同质反应系统中的使用.在典型的储存条件下和有详细记录的再活动特征稳定有助于其在工业和实验室应用中的用途.

结构式图片

相似化合物

7737-62-4 53605-94-0 1779-60-8

上下游产品

4-methyleneoxetan-2-one butan-1-ol acetic acid butyl ester sodium butanolate n-butyl 3-hydroxybutyrate 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid 2-benzyl ester 4-ethyl ester 2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid dibutyl ester 3-phenylhydrazono-butyric acid butyl ester

合成工艺路线路线简述

    乙酸丁酯置于乙醚,氨,Sodium Amide体系中,化学反应生成 乙酰乙酸正丁酯
    参考文献:Shivers; Dillon; Hauser,Journal Of The American Chemical Society,1947,Vol. 69,P. 120
    标题:Shivers; Dillon; Hauser,Journal Of The American Chemical Society,1947,Vol. 69,P. 120

    海关参考信息

    专利信息


    专利号:US-6933385-B2
    优先权日:2001-08-03
    标题 :Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use
    发明人:WESTERMANN JURGEN; PLATZEK JOHANNES; PETROV ORLIN
    权利人:SCHERING AG
    摘要:The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.

    专利号:US-9080119-B2
    优先权日:2011-11-10
    标 题:Synthesis of high caloric fuels and chemicals including pentanol from coal, natural gas, and biomass
    发明人:HENRI JOHN; ZYGMUNT JAN; BERGGREN MARK; ZUBRIN ROBERT
    权利人:PIONEER ENERGY INC; Pioneer Energy
    摘要:In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc.

    专利号:US-9611186-B2
    优先权日:2011-11-10
    标 题 :Synthesis of high caloric fuels and chemicals via ketene and diketene intermediates
    发明人:HENRI JOHN; ZYGMUNT JAN; BERGGREN MARK; ZUBRIN ROBERT
    权利人:PIONEER ENERGY INC; Pioneer Energy
    摘要:In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc.

    专利号:US-2004249219-A1
    优先权日:2000-07-05
    标题 :Method of making teprenone
    发明人:SAUCY GABRIEL G
    摘要:The invention is directed to an efficient and economical method of making teprenone. Teprenone is synthesized by converting geranylgeraniol to teprenone by a novel route. The method of synthesis can begin with geranylgeraniol obtained from a biological source such as fermentation of a microorganism capable of producing geranylgeranyl or enzymatic synthesis in a cell free system to produce predominantly the 5E isomer of teprenone. The chemical synthesis proceeds with retention of configuration such that the teprenone produced has the isomeric configuration of the geranylgeraniol starting material.

    专利号:CN-116904543-A
    优先权日:2023-09-07
    标 题:Application and synthesis method of a dehydrogenase in the synthesis of R-configuration Boseine

    专利号:CN-116904543-B
    优先权日:2023-09-07
    标 题:Application and synthesis method of a dehydrogenase in the synthesis of R-configuration Boseine
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    合成参考文献


    摘要:Tymoshenko, D. O., Science of Synthesis Knowledge Updates, (2012) 3, 370.
    摘要:Chemla, F.; Ferreira, F.; Pérez-Luna, A., Science of Synthesis Knowledge Updates, (2012) 1, 461.
    摘要:Johnson, J. B., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 783.
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