CAS: 505-23-7; 1,3-Dithiane

相似化合物

6007-26-7 13411-42-2 6007-23-4

上下游产品

CAS号109-80-8 1,3-丙二硫醇 | CAS号109-87-5 甲缩醛 | CAS号75-11-6 二碘甲烷 | CAS号69178-10-5 1,3-Dithiane,2-... | CAS号462-95-3 二乙氧基甲烷 | CAS号50-00-0 甲醛 | CAS号120-57-0 胡椒醛 | CAS号13411-42-2 2-三甲基硅基-1,3-二噻烷 | CAS号75-15-0 二硫化碳 | CAS号109-64-8 1,3-二溴丙烷 | CAS号111897-16-6 2-tetradecyl-1,... | CAS号111741-88-9 2-[4-(1,3-dithi... | CAS号104863-72-1 Ethanone, 1-(1,... | CAS号5425-44-5 2-苯基-1,3-二噻烷 | CAS号53885-35-1 盐酸噻氯匹定 | CAS号14947-48-9 2-(1,3-二噻烷-2-基)乙醇 | CAS号14758-37-3 2-methylsulfany... | CAS号39141-54-3 2,2-bis(methylt... | CAS号21777-32-2 hexanal-1,3-dithiane | CAS号26413-18-3 1,3-dithiane 1,...

1,3-Dithiane 1-Oxide置于1,3,5-三甲氧基苯,草酰氯体系中,用 二氯甲烷 作为反应溶剂,以69%的收率获得产物1,3-二噻烷
参考文献:来自氯ulf盐的亲电子氯:亚砜的高度化学选择性还原.
标题:来自氯ulf盐的亲电子氯:亚砜的高度化学选择性还原.
摘要:本文中,我们基于氯ulf盐的新应用描述了亚砜的选择性后期脱氧,并展示了使用这些亚砜原位反应生成的物种作为亲电氯源的新工艺.首次描述了使用高度亲核的1,3,5-三甲氧基苯(tmb)作为还原剂,并将其用于简单和功能化亚砜的脱氧.该方法易于操作,经济,适用于克级操作,并且易于应用于多官能分子,如超过45个实例(包括商业药物和类似物)所示.我们还报告了定义更具反应性的亚砜的竞争实验的结果,并且我们根据底物和产品的观察结果提出了一种机械的方案.
DOI:10.1002/chem.202001815

专利信息

专利号:WO-2024013633-A1
优先权日:2022-07-11
标 题 :Process for the synthesis of vitamin k2
发明人：SHASTRI MAYANK; BAIKAR MRUNALI H; VORA PARIN K; BNS RAJU
权利人:SYNERGIA LIFE SCIENCES PVT LTD
摘要:The present disclosure relates to the synthesis of Vitamin K2 bearing varying prenyl side chains. The synthesis comprises the reaction of phenyl sulfone of tert-butyl dimethyl silyl (TBDMS) protected mono prenyl menadiol with prenyl halides bearing varying prenyl units in the presence of the phase transfer catalyst followed by reductive desulphonation to yield TBDMS ether of Vitamin K2. The TBDMS ether is then oxidized in the presence of chromium trioxide and periodic acid to yield the corresponding Vitamin K2.

专利号:WO-2012047907-A9
优先权日:2010-10-04
标题 :Synthesis of c5-substituted tetracyclines, uses thereof, and intermediates thereto
发明人：MYERS ANDREW G; WRIGHT PETER M; HECKER EVAN
权利人:HARVARD COLLEGE; MYERS ANDREW G; WRIGHT PETER M; HECKER EVAN
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for a wide variety of substituents at position 5 of the tetracycline ring system.

专利号:US-9688644-B2
优先权日:2009-04-30
标 题 :Synthesis of Tetracyclines and intermediates thereto
发明人：MYERS ANDREW G; KUMMER DAVID A; LI DERUN; HECKER EVAN; DION AMELIE; WRIGHT PETER M
权利人:HARVARD COLLEGE
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.

专利号:US-8957230-B2
优先权日:2011-06-30
标 题 :Synthesis of cleistanthin A and derivatives thereof
发明人：MULIK NILESH SHRIDHAR; PANGHAVANE KAILASH DATTATRAYA
权利人:MULIK NILESH SHRIDHAR; PANGHAVANE KAILASH DATTATRAYA
摘要:The present invention provides a method for preparing Cleistanthin A, a diphyllin glycoside, derivatives thereof and intermediates thereto. In particular the present invention provides in one of the aspect a method for synthesis of compound of formula D a key intermediate of diphyllin, which can be carried out in a shorter duration and at an ordinary temperature.

专利号:US-6472534-B2
优先权日:1999-10-21
标 题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
发明人：BORER BENNETT C; ZOOK SCOTT E; BUSSE JULIETTE K
权利人:AGOURON PHARMA
摘要:Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises converting tetrohydran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir. Also disclosed is a method for the preparation of a chiral amino alcohol from an epoxy-tetrahydrofuran.

专利号:US-2025171493-A1
优先权日:2022-03-05
标题 :Processes for synthesis of withanolides and withaferins and analogs thereof
发明人：LOPCHUK JUSTIN MATTHEW
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of withanolides such as Withanolide A and Withanolide D.