CAS: 42294-52-0; S-(4-Methylbenzyl)-L-Cysteine

上下游产品

CAS号52-90-4 L-半胱氨酸 | CAS号104-82-5 对甲基氯苄 | CAS号52-89-1 L-半胱氨酸盐酸盐(无水物) | CAS号589-18-4 4-甲基苄醇 | CAS号104-81-4 4-甲基溴苄 | CAS号198991-77-4 (4R)-2-(4-methy... | CAS号61925-77-7 N-叔丁氧羰基-S-(4-甲基... | CAS号56-89-3 L-胱氨酸 | CAS号136050-67-4 Fm°C-S-(4-甲基苄基)...

📜(2Rs,4R)-2-(4-Methylphenyl)-1,3-Thiazolidine-4-Carboxylic Acid置于三乙基硅烷,三氟乙酸体系中,用 二氯甲烷 作为反应溶剂,化学反应 16.0H,反应生成 L-半胱氨酸
参考文献:引入巯基苄基保护基的两种新方法
标题:引入巯基苄基保护基的两种新方法
摘要:描述了两种新的硫醇苄基化方法:A)用对位取代的苄基阳离子直接进行s-烷基化;b)2-氨基硫醇的还原性s-烷基化.两种方法均提供了以高收率引入苄基型保护基的有效途径.
DOI:10.1016/0040-4039(94)88305-X

专利信息

专利号:US-2025289851-A1
优先权日:2022-04-22
标 题:Cyclic peptides for delivering therapeutics
发明人：DOUGHERTY PATRICK; TOTARO KYLE A; DOMBROSKI AMANDA; GIESLER RILEY; ZHOU MING; STREETER MATTHEW; GOFFIN ALEC; QIAN ZIQING
权利人:ENTRADA THERAPEUTICS INC
摘要:The present disclosure relates to the synthesis of cyclic peptides that are able to effectively deliver cargo, e.g., a therapeutic moiety (TM), inside a cell to treat a variety of conditions and diseases.

专利号:US-4960881-A
优先权日:1984-02-16
标 题 :α-chlorinated carbonates, their method of manufacture and application in the protection of the amine functions of amino acids
发明人：BARCELO GERARD; SENET JEAN-PIERRE; SENNYEY GERARD
权利人:POUDRES & EXPLOSIFS STE NALE
摘要:The invention relates to carbonates of formula: ##STR1## in which X is a fluorine, chlorine or bromine atom and R 1 is different from the ##STR2## group and represents: a substituted or non-substituted, saturated or unsaturated, aliphatic, araliphatic, primary, secondary, tertiary or cycloaliphatic radical. These α-chlorinated carbonates are prepared by the action of a compound of formula R 1 OH on a chloroformate of formula: ##STR3## in a solvent medium in the presence of an acid scavenger which is added after the two preceding compounds. They are used to block the amine function of amino acids. The α-chlorinated carbonate and amino acid are reacted in a solvent medium at a temperature of -5° to 100° C. in the presence of an acid scavenger. Blocked amines are very useful in peptide synthesis.