CAS: 38444-81-4; 2,5,3'-Trichlorobiphenyl
该化合物是一种氯化联苯化合物,是称为多氯联苯(PCB)的更大类别化学品的一部分;它有两枚联苯环,由一个单一的联结连接,其中三个氯原子在2,3'替换,联苯结构上的位置为5个;该化合物一般是室内温度时的白色到轻黄色固体,以其疏水性闻名,使其在水中溶解性差,但在有机溶剂中溶解. 2,3',5-三氯联苯表现出热稳定性和耐降解性,这助长了其在环境中的持久性.它被用于各种工业用途,包括电容器和变压器中的电流.然而,由于其毒理学特征,包括潜在的致癌性和内分泌干扰效应,许多国家对其生产和使用进行了严格的管制或禁止.环境监测对于评估其存在和影响至关重要,因为它可能积累在食物链中,并对人类健康和生态系统构成风险.
- 英文名称2,5,3'-Trichlorobiphenyl
- 中文名称2,3',5-三氯联苯
- IUPAC名称1,4-dichloro-2-(3-chlorophenyl)benzene
- 其它别名2,3',5-Trichloro-1,1'-biphenyl; 2,3',5-Trichlorobiphenyl; 2,5,3'-Trichlorobiphenyl; 3,2',5'-Trichlorobiphenyl; PCB 26
- CAS编号38444-81-4
- MFCD编号:MFCD00671093
- FDA UNII编号:98H9867N6L
- 分子式:C12H7Cl3分子量:257.54
- 产品CID: 1396600
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
2,2',5,5'-Tetrachlorobiphenyl合成工艺路线路线简述
📜1-氯-3-碘苯,1,4-二氯-2-碘苯置于铜体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应生成2,3',5-三氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
Doi:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
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📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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