CAS: 2942-58-7; Diethyl Phosphorocyanidate

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4851-51-8 682-30-4 2537-48-6

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CAS号143-33-9 氰化钠 | CAS号814-49-3 氯磷酸二乙酯 | CAS号151-50-8 氰化钾 | CAS号762-04-9 亚磷酸二乙酯 | CAS号74-90-8 氢氰酸 | CAS号2757-23-5 氯羰基亚磺酰氯 | CAS号33326-12-4 Phosphor°Cyanid... | CAS号506-68-3 溴化氰 | CAS号122-52-1 亚磷酸三乙酯 | CAS号4295-99-2 4-氰基四氢吡喃 | CAS号4552-43-6 4-氯-2-氰基喹啉 | CAS号2046-18-6 4-苯基丁腈 | CAS号767-00-0 4-羟基苯甲腈 | CAS号78-40-0 磷酸三乙酯 | CAS号87174-55-8 diethyl (3-(2-c... | CAS号87174-57-0 diethyl (3-(p-t... | CAS号87174-58-1 diethyl (3-(4-n... | CAS号26218-72-4 3,4-bis(4-chlor...

📜二乙氧基膦基氢氰酸 以 二甲基亚砜 用作溶剂,以82%的收率获得氰基磷酸二乙酯
参考文献:Pudovik,A. N.; Nazmutdinova,V. N.,Journal Of General Chemistry Of The Ussr,1988,Vol. 58,# 10,P. 1973-1976
标题:Pudovik,A. N.; Nazmutdinova,V. N.,Journal Of General Chemistry Of The Ussr,1988,Vol. 58,# 10,P. 1973-1976

专利信息

专利号:WO-2024181781-A1
优先权日:2023-02-27
标 题:Substrate for synthesis of biological polymers having anti-aggregation function and biological polymer synthesis method using same
发明人：JANG MYOUNG HOON; CHOI JAE SUN
权利人:SP2 TX INC
摘要:The present invention relates to a substrate for the synthesis of biological polymers having an anti-aggregation function, and a biological polymer synthesis method using the substrate. The substrate according to an aspect may have anti-aggregation functionality to enable high-yield and high-purity processes in the synthesis of biological polymers.

专利号:US-7230101-B1
优先权日:2002-08-28
标 题:Synthesis of methotrexate-containing heterodimeric molecules
发明人：MURTHI KRISHNA K; SMITH CHASE C
权利人:GPC BIOTECH INC
摘要:The present invention relates to novel compositions of methotrexate-containing heterodimeric probe molecules, also known as chemical inducers of dimerization (CID), useful in three-hybrid assays. The invention further relates to synthesis of said compositions and their intermediates. Another aspect of the invention is a method for using the heterodimeric probe molecules described herein in drug screens to identify potential protein targets to a given ligand, optimize protein-ligand interactions, or identify potential ligands for a given protein target. In certain embodiments, the invention contemplates the synthesis of the following methotrexate-containing heterodimeric probe:

专利号:WO-0100609-A1
优先权日:1999-06-29
标题:Method for synthesis of n-homocysteine thiolactonyl retinamide
发明人：KAZIMIR MICHAEL; WILSON RAY E II
权利人:UNIV BAYLOR; KAZIMIR MICHAEL; WILSON RAY E II
摘要:The present invention describes methods of synthesis for N-homocysteine thiolactonyl retinamide (thioretinamide), a compound that has anticancer and antiatherogenic properties. The present invention further describes methods for the synthesis of N-homocysteine thiolactonyl retinamido cobalamin (thioretinaco), a compound that has potential anticancer, antineoplastic, antiviral, and antiatherogenic properties.

专利号:WO-2024062080-A1
优先权日:2022-09-21
标题:Improved synthesis of psilocybin derivatives
发明人：HAMMES CHRISTIAN; STÖCKLI STEFAN
权利人:CARBOGEN AMCIS AG; AAMANYA AG
摘要:The present invention relates to an improved synthesis of psilocybin and alkyl- derivatives of psilocybin such as ethocybin (4-phosphoryloxy-N,N-diethyltryptamine, also known as phosphoryloxy-DET, PO-DET or CEY-39) and furthermore, relates to intermediates useful in the synthesis of these compounds.

专利号:US-2019177392-A1
优先权日:2014-09-23
标 题 :Synthesis of glp-1 peptides
发明人：PENIAS NAVON SHARON; NAVEH SHIRLY; VASILEIOU ZOI; BARLOS KONSTANTINOS
权利人:NOVETIDE LTD
摘要:Disclosed are processes for the synthesis of GLP-1 peptides, such as liraglutide and semaglutide, and a process for purifying liraglutide.

专利号:US-5554725-A
优先权日:1994-09-14
标题:Synthesis of dolastatin 15
发明人：PETTIT GEORGE R
权利人:UNIV ARIZONA
摘要:The present invention relates to the synthesis of natural (-)- dolastatin and the elucidation of the absolute configuration of this important sea hare constituent. A segment synthetic strategy was utilized for obtaining the Dolabella auricularia (Indian Ocean sea hare) depsipeptide dolastatin 15. Reaction of protected (S)-Hiva-(S)-Phe (2c) with isopropenyl chloroformate followed by Meldrum's ester, cyclization (2c→3a) of the product in toluene and finally methylation afforded the key (S)-dolapyrrolidine (Dpy) derivative (3b). Condensation of tripeptide (8) with the three unit Dpy segment (5b) followed by deprotection and coupling (diethyl phosphorocyanidate) led to dolastatin 15 in 11% overall yield. The powerful and selective activity of dolastatin 15 against the U.S. National Cancer Institute's panel of human cell lines is reported.