CAS: 230299-21-5; 4,4,4',4',6,6'-Hexamethyl-2,2'-Bi(1,3,2-Dioxaborinane)

相似化合物

230299-46-4 23894-82-8 73183-34-3

上下游产品

4,4,6-Trimethyl-1,3,2-Dioxaborinane

2-甲基-2,4-戊二醇置于2,6-二叔丁基-4-甲基苯酚,C25H36Fen2Si体系中,用 二氯甲烷,甲苯 用作溶剂,化学反应 15.0H,反应生成双联(2-甲基-2,4-戊二醇)硼酸酯
参考文献:一种制备联硼酸酯的工艺
标题:一种制备联硼酸酯的工艺
摘要:本发明公开了一种制备联硼酸酯的工艺.硼烷络合物和相应的二醇反应生成相应的醇硼烷,随后在铁催化剂存在下发生自身偶联形成联硼酸酯.该方法合成步骤短,安全性高,反应条件温和,适合多种联硼酸酯的合成.

专利信息

专利号:EP-2647639-A1
优先权日:2012-04-06
标题:ß-boration of alkene and alkyne intermediates
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-borated compounds can be used as intermediates in the synthesis of pharmaceutically active agents such as Sitagliptin.

专利号:US-11345665-B2
优先权日:2017-11-15
标题:Chiral 1,3-diarylimidazolium salt carbene precursor, synthesis method therefor, metal salt compound and application thereof
发明人：SHI SHILIANG; CAI YUAN; Yang Xintuo; LI FENG
权利人:SHANGHAI INST ORGANIC CHEMISTRY CAS
摘要:Chiral 1, 3-diarylimidazole salt carbene precursors, their methods of preparation, particularly transition metal complexes and their use in chemical synthesis are provided. In particular, an air and moisture stable chiral 1, 3-diarylimidazole carbene precursor Cu (I) complex has been prepared and applied to highly regio- and enantioselective Markovnikov hydroboration of unactivated terminal alkenes to form chiral boronic esters. Moreover, these new chiral NHCs can be potentially applied in various metal-catalyzed asymmetric transformations.

专利号:US-8697730-B2
优先权日:2007-10-26
标题 :5-lipoxygenase activating protein (FLAP) inhibitor
发明人：REWOLINSKI MELISSA VIRGINIA; SCHAAB KEVIN MURRAY; KING CHRISTOPHER DAVID; STOCK NICHOLAS SIMON
权利人:REWOLINSKI MELISSA VIRGINIA; SCHAAB KEVIN MURRAY; KING CHRISTOPHER DAVID; STOCK NICHOLAS SIMON; PANMIRA PHARMACEUTICALS LLC
摘要:Described herein are methods for the synthesis of 3-[5-(pyridin-2-ylmethoxy)-3-(2-methyl-2-propylthio)-1-[4-(2-methoxypyridin-5-yl)benzyl]-indol-2-yl]-2,2-dimethyl-propionic acid, pharmaceutically acceptable salts, pharmaceutically acceptable solvates thereof. Also described are pharmaceutical compositions suitable for oral administration to a mammal that include, as well as methods of using such oral pharmaceutical compositions for treating respiratory conditions or diseases, as well as other leukotriene-dependent or leukotriene mediated conditions or diseases.

专利号:US-12202782-B2
优先权日:2020-11-19
标 题:Processes and intermediates for preparing MCL1 inhibitors
发明人：DIXON DARRYL D; ISCHAY MICHAEL A; JOHNSON TREVOR C; MERIT JEFFREY E; REGENS CHRISTOPHER S; STANDLEY ERIC A; STEINHUEBEL DIETRICH P
权利人:GILEAD SCIENCES INC
摘要:The present disclosure relates to methods and intermediates for the synthesis of certain compounds that inhibit MCL1, for use in the treatment of cancers.

专利号:CA-3198798-A1
优先权日:2020-11-13
标 题 :Improved synthesis of crac channel inhibitors

专利号:EP-4243813-A1
优先权日:2020-11-13
标题 :Improved synthesis of crac channel inhibitors