CAS: 143426-49-7; (4-Pyrazol-1-Yl-Phenyl)Methanol

该化合物是一种有机化合物,其特点是,一个与四代苯基组相连的甲基环桥上存在一个酚氢化石组(-OH),该组与四代苯基组相连,而该组又被一个丙烯基苯基类替代,该组又被一个丙烯基苯基替代.该组物的特性表现为苯和丙诺基衍生物的典型性质,包括因聚氧基体和阳极环中的氮原子而具有的潜在氢结合能力.该组物可能显示生物活动,使其对药用化学感兴趣.该组物的芳香结构可能有助于其稳定性和再活性.此外,苯甲醇环的存在可带来独特的电子特性,影响其与其他分子的互动.

结构式图片

相似化合物

16209-00-0 99662-34-7 400750-29-0

物理性质

MSDS等安全信息

欧盟法规

C&L通报

上下游产品

CAS号143426-47-5 4-(1-吡唑基)苯甲酸甲酯 | CAS号451-46-7 4-氟苯甲酸乙酯 | CAS号99662-34-7 4-(1H-吡唑-1-基)苯甲醛 | CAS号65476-24-6 [4-(1H-吡唑-1-基)苯基]乙酸

合成工艺路线路线简述

    📜4-(1-吡唑)苯甲酸甲酯置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 用作溶剂,化学反应 2.0H,以91%的收率获得1-(4-羟甲基苯基)吡唑
    参考文献: Pyrrolidine Glycosidase Inhibitors[fr] Inhibiteurs De Pyrrolidine Glycosidase
    标题: Pyrrolidine Glycosidase Inhibitors[fr] Inhibiteurs De Pyrrolidine Glycosidase
    摘要:式(i)中a,W,R3B,Z和p的含义如权利要求所述,可用于治疗tau病和阿尔茨海默病.

    海关参考信息

    专利信息


    专利号:US-9708278-B2
    优先权日:2013-11-27
    标 题 :Substituted 4-benzyl-3,4-dihydro-2H-benzo[B][1,4]oxazine-2-carboxamide analogs as positive allosteric modulators of muscarinic acetycholine receptor M1
    发明人：LINDSLEY CRAIG W; CONN P JEFFREY; STAUFFER SHAUN R; PANARESE JOSEPH D
    权利人:UNIV VANDERBILT
    摘要:In one aspect, the invention relates to N-substituted 3,4-dihydro-benzo[£][1,4]oxazine-2-carboxamide analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

    专利号:US-7825149-B2
    优先权日:2006-01-19
    标 题 :Substituted imidazoles
    发明人：CHUBB NATHAN ANTHONY LOGAN; COX MARK ROGER; DAUVERGNE JEROME SEBASTIEN; EWIN RICHARD ANDREW; LAURET CHRISTELLE
    权利人:PFIZER LTD
    摘要:This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Stanovnik, B.; Svete, J., Science of Synthesis, (2002) 12, 125.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知