CAS: 1118-90-7; (S)-2-Aminoadipic Acid

上下游产品

CAS号159947-36-1 (S)-2-(N-benzyl... | CAS号24325-14-2 CBZ-L-2-氨基己二酸 | CAS号7433-32-1 L-高谷氨酰胺 | CAS号15753-50-1 顺-1,2-环己基二甲醇 | CAS号102307-20-0 2-ketoadipate m... | CAS号77302-72-8 B°C-L-2-氨基己二酸 | CAS号81323-62-8 (S)-tert-butyl ... | CAS号2389-60-8 Z-丁氧羰基赖氨酸 | CAS号2418-95-3 N(e)-B°C-L-赖氨酸 | CAS号83793-27-5 2-amino-6-oxo-6... | CAS号34622-39-4 (S)-2-哌啶酮-6-羧基 酸 | CAS号110-94-1 戊二酸 | CAS号3184-35-8 2-氧代己二酸单钠盐 | CAS号56-87-1 L-赖氨酸 | CAS号24325-14-2 CBZ-L-2-氨基己二酸 | CAS号84246-49-1 苄基(2S)-2-羰基苄氧基氨... | CAS号7620-28-2 D-2-氨基己二酸 | CAS号77302-72-8 B°C-L-2-氨基己二酸 | CAS号158414-69-8 methyl (2S)-6-o... | CAS号128726-47-6 (S)-6-(羟甲基)哌啶-2-酮

Z-L-Gluome 反应生成L-2-氨基己二酸
参考文献:苄氧羰基谷氨酸酐与重氮甲烷的反应
标题:苄氧羰基谷氨酸酐与重氮甲烷的反应
摘要:
Doi:10.1016/s0040-4039(01)83767-9

专利信息

专利号:US-8809526-B2
优先权日:2010-07-19
标题 :Synthesis of cyclopentaquinazolines
发明人：KERSCHEN JAMES ALAN; BRIDGES ALEXANDER JAMES; DALZIEL SEAN MARK; DAPREMONT Olivier; KIM HYUNJUNG; THOMPSON ANDREW S; ZELLER JAMES ROBERT
权利人:KERSCHEN JAMES ALAN; BRIDGES ALEXANDER JAMES; DALZIEL SEAN MARK; DAPREMONT Olivier; KIM HYUNJUNG; THOMPSON ANDREW S; ZELLER JAMES ROBERT; ONYX PHARMA INC
摘要:A method of producing 6-amino-cyclopenta[g]quinazolines, in enantiomerically enriched form, is provided. In particular, the method may be applicable to the synthesis of N—{N-{4-[N-((6S)-2 -hydroxymethyl-4-oxo-3,4,7,8-tetrahydro-6H-cyclo-penta[g]quinazolin-6-yl)-N-(prop-2 -ynyl)amino]benzoyl}-L-γ-glutamyl}-D-glutamic acid (ONX-0801).

专利号:WO-9217496-A1
优先权日:1991-03-18
标题 :Isolation and sequence of the acetyl coa:deacetylcephalosporin acetyltransferase gene
发明人：MATHISON LORILEE; SOLIDAY CHARLES L; RAMBOSEK JOHN A
权利人:PANLABS INC
摘要:The invention relates to a DNA sequence with a nucleotide sequence encoding a polypeptide in a host cell having Cephalosporin C synthetase (DAC acetyltransferase) activity which is the last enzyme in the synthesis of cephalosporins. Embodiments of the invention relate to methods and compositions for detecting the gene or its product, mutants and hybrids of the gene, replicative cloning and expression vectors, and processes for preparing recombinant DAC acetyltransferase polypeptide useful for host cell synthesis of, as well as cell-free synthesis of natural and synthetic cephalosporin antibiotics.

专利号:US-9458188-B2
优先权日:2010-12-22
标 题 :Efficient peptide couplings and their use in the synthesis and isolation of a cyclopenta (G) quinazoline trisodium salt
发明人：KERSCHEN JAMES ALAN; BRIDGES ALEXANDER JAMES; CHOUBAL MILIND D; DALZIEL SEAN MARK; JACKS THOMAS ELLIOTT; THOMPSON ANDREW S; ZELLER JAMES ROBERT
权利人:KERSCHEN JAMES ALAN; BRIDGES ALEXANDER JAMES; CHOUBAL MILIND D; DALZIEL SEAN MARK; JACKS THOMAS ELLIOTT; THOMPSON ANDREW S; ZELLER JAMES ROBERT; BTG INT LTD
摘要:A new method for the synthesis of L-Glutamyl-γ-D-Glutamic acid and its use in the synthesis of (2R)-((4S)-carboxy-4-(4,N-(((6S)-2-(hydroxymethyl)-4-oxo-3,4,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)-N-(prop-2-ynyl)amino)benzamido)butanamido)pentanedioic acid, 1 are provided. Also provided is an efficient method for the isolation and purification of the trisodium salt of the abovementioned acid, 2, in a form suitable for long term storage and use in a parenteral dosing form.

专利号:US-2008031812-A1
优先权日:1999-06-02
标 题:Redox-stable, non-phosphorylated cyclic peptide inhibitors of sh2 domain binding to target protein, conjugates, thereof, compositions and methods of synthesis and use
发明人：ROLLER PETER P; LONG YA-QIU; LUNG FENG-DI T; KING C RICHTER; YANG DAJUN; VOIGT JOHANNES H
权利人:GOVERNMENT OF THE USA REPRESEN; UNIV GEORGETOWN
摘要:A compound of formula: n n nin which (i) aa 1 is Adi and aa 4 is Glu or (ii) each of aa 1 and aa 4 is Adi, L is sulfur, sulfoxide, oxygen or methylene, which compound (and its conjugates) bind to an SH2 domain in a protein comprising an SH2 domain, is non-phosphorylated, is redox-stable in vivo, is characterized by an IC 50 in vivo of less than about 4.0 μM with respect to the SH2 domain in Grb2, and, upon binding to the SH2 domain of Grb2, has a turn conformation. A conjugate comprising a compound as described above and a carrier agent, a composition comprising (i) a compound or a conjugate as described above and (ii) a carrier, a method of inhibiting binding of an SH2 domain in a protein comprising an SH2 domain to a target protein in an animal, wherein the SH2 domain is contacted with a target protein-binding inhibiting effective amount of a compound or a conjugate as described above, and a method of synthesizing such conjugates.

专利号:US-2008131925-A1
优先权日:2004-12-10
标题 :Production of Beta-Lactams in Single Cells
发明人：BERG MARCO ALEXANDER VAN DEN; BOVENBERG ROELOF ARY LANS; NOORMAN HENDRIK JAN; ROMEIN BASTIAAN
权利人:BERG MARCO ALEXANDER VAN DEN; BOVENBERG ROELOF ARY LANS; NOORMAN HENDRIK JAN; ROMEIN BASTIAAN
摘要:The present invention describes the transformation of a microorganism that does not naturally produce a β-lactam compound with polynucleotides involved in the biosynthesis of β-lactam compounds and the use of such transformed microorganisms in the production of β-lactam compounds or in the identification of genes or factors involved in the synthesis of a β-lactam compound.

专利号:US-2022243244-A1
优先权日:2019-10-10
标 题 :Compositions and methods for in vivo synthesis of unnatural polypeptides
发明人：ROMESBERG FLOYD E; FISCHER EMIL C; HASHIMOTO KOJI; FELDMAN AARON W; DIEN VIVIAN T; ZHANG YORKE
权利人:SCRIPPS RESEARCH INST
摘要:Disclosed herein are compositions, methods, and kits for a cell incorporating unnatural amino acids into an unnatural polypeptide. Also disclosed herein are compositions, methods, and kits for increasing activity and yield of the unnatural polypeptide synthesized by the cell.