CAS: 988-75-0; Z-Glu-Tyr-Oh

上下游产品

CAS号101982-64-3 Z-Glu-Tyr-OEt | CAS号122315-73-5 N-(O-ethyl-N-be... | CAS号949-67-7 L-酪氨酸乙酯 | CAS号4124-76-9 benzyl N-(2,6-d... | CAS号35726-62-6 N-Cbz-L-谷氨酸-5-乙酯 | CAS号4652-65-7 N-苄氧羰基-L-谷氨酸- 5-甲酯 | CAS号1155-62-0 N-苄氧羰基-L-谷氨酸 | CAS号60-18-4 L-酪氨酸 | CAS号3422-39-7 H-Glu-Tyr-OH

📜L-酪氨酸乙酯置于sodium Hydroxide,乙酸乙酯体系中,化学反应生成 Z-甘氨酰酪氨酸
参考文献:Bergmann Et Al.,Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie,1934,Vol. 224,P. 17,24
标题:Bergmann Et Al.,Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie,1934,Vol. 224,P. 17,24

专利信息

专利号:US-7179794-B2
优先权日:1998-06-08
标题 :Multivalent macrolide antibiotics
发明人：GRIFFIN JOHN H; PACE JOHN L
权利人:THERAVANCE INC
摘要:Disclosed are multibinding compounds which include macrolide antibiotics, aminoglycosides, lincosamides, oxazolidinones, streptoramins, tetracycline and/or other compounds which bind to bacterial ribosomal RNA and/or to one or more proteins involved in ribosomal protein synthesis in the bacterium, which are useful in treating bacterial infections. The compounds adversely affect protein expression and have an antibacterial effect. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is macrolide antibiotic, aminoglycoside, lincosamide, oxazolidinone, streptogramin, tetracycline or other compound which binds to bacterial ribosomal RNA and/or one or more proteins involved in ribosomal protein synthesis in the bacterium.