CAS: 6705-03-9; 2-Amino-5-Methoxybenzoic Acid

上下游产品

CAS号1882-69-5 5-甲氧基-2-硝基苯甲酸 | CAS号1006-94-6 5-甲氧基吲哚 | CAS号100174-55-8 5,5'-dimethoxy-... | CAS号180690-91-9 methyl 2-(3,3-d... | CAS号2581-34-2 4-硝基间甲苯酚 | CAS号5367-32-8 3-甲基-4-硝基苯甲醚 | CAS号6335-41-7 2-羟基亚胺-N-(4-甲氧基... | CAS号20265-97-8 对茴香胺盐酸盐 | CAS号104-94-9 对甲氧基苯胺 | CAS号54413-93-3 2-碘-5-甲氧基苯甲酸 | CAS号37795-77-0 5-甲氧基靛红酸酐 | CAS号42465-53-2 2'-氨基-4'-甲氧基苯乙酮 | CAS号50424-28-7 4-氯-6-甲氧基喹唑啉 | CAS号20197-97-1 2-氯-6-甲氧基喹唑啉-4(3H)-酮 | CAS号19532-69-5 2,2-Dithiobis(5... | CAS号194715-44-1 6-methoxy-3-pro... | CAS号214971-09-2 2-氨基-n,5-二甲氧基-n... | CAS号26831-52-7 Benzaldehyde,2-... | CAS号850424-11-2 2-氯-6-甲氧基喹唑啉

5-甲氧基-2-硝基苯甲酸置于palladium 10% On Activated Carbon,氢气体系中,用 乙醇 作为反应溶剂,20.0 °C,101.33 Kpa 条件下,以100%的收率获得产物2-氨基-5-甲氧基苯甲酸
参考文献:2,3-二氢吡咯并[1,2-A]喹唑啉-5(1H)-一的合成与反应性
标题:2,3-二氢吡咯并[1,2-A]喹唑啉-5(1H)-一的合成与反应性
摘要:尊重并祝福我们的朋友对他的70之际迪特.恩德斯专用个生日 抽象的 报道了一种改进的,可扩展的合成路线,该路线合成了喹唑啉酮天然产物2,3-二氢吡咯并[1,2-A]喹唑啉-5(1 H)-One.探索了该方法在类似物合成和相关天然产物合成中的适用性.最后,报道了支架对多种亲电试剂的反应性,立体选择性地产生产物. 报道了一种改进的,可扩展的合成路线,该路线合成了喹唑啉酮天然产物2,3-二氢吡咯并[1,2-A]喹唑啉-5(1 H)-One.探索了该方法在类似物合成和相关天然产物合成中的适用性.最后,报道了支架对多种亲电试剂的反应性,立体选择性地产生产物.
DOI:10.1055/s-0035-1562792

专利信息

专利号:US-2012189547-A1
优先权日:2009-10-08
标 题 :[18f] labelled analogues of flumazenil as in vivo imaging agents
发明人：WOODCRAFT JOHN; JONES CLARE L; GAETA ALESSANDRA; TRIGG WILLIAM JOHN; JONES PAUL ALEXANDER; PLANT STUART
权利人:WOODCRAFT JOHN; JONES CLARE L; GAETA ALESSANDRA; TRIGG WILLIAM JOHN; JONES PAUL ALEXANDER; PLANT STUART
摘要:The present invention provides radiofluorinated compounds useful for in vivo imaging GABA A receptors. Also provided by the present invention is a method of synthesis for the radiofluorinated compounds of the invention, in particular an automated method of synthesis. A further aspect of the invention is a cassette suitable for carrying out the automated method of synthesis of the invention.

专利号:US-6187923-B1
优先权日:1998-11-09
标题 :Process for the synthesis of quinazolinones
发明人：DENER JEFFREY MARK; LY CUONG QUOC
权利人:AXYS ADVANCED TECHNOLOGIES INC
摘要:The present invention provides a process for synthesizing a compound or a library of compounds of Formula 1A and 1B:

专利号:WO-0027831-A1
优先权日:1998-11-09
标题 :Process for the synthesis of quinazolinones

专利号:US-2011263569-A1
优先权日:2007-08-22
标 题 :Ryanodine channel binders and uses thereof
发明人：COREY ELIAS JAMES
权利人:HARVARD COLLEGE
摘要:Increasing the affinity of calstabin-2 for the cardiac calcium channel RyR2 and thereby stabilizing the channel in the closed state has recently been identified as novel mechanism for treating heart failure, particularly ventricular arrhythmias. JTV-519, a 1,4-benzothiazepine derivative, has been shown to stabilize the calstabin2/RyR2 complex. Novel derivatives of JTV-519 that may be useful in treatment or prevention of heart failure, atrial fibrillation, or exercise-induced cardiac arrhythmias are provided. Synthetic methodology and intermediates in the synthesis of the inventive JTV-519 derivatives are also described.

专利号:EA-011357-B1
优先权日:2003-10-07
标 题 :METHOD OF SYNTHESIS OF BENZOTHIAZEPINE COMPOUNDS

专利号:WO-9845272-A1
优先权日:1997-04-07
标题:Topoisomerase inhibitors
发明人：DEADY LESLIE WILLIAM; DENNY WILLIAM ALEXANDER; KAYE ANTHONY JAMES
权利人:UNIV LATROBE; DEADY LESLIE WILLIAM; DENNY WILLIAM ALEXANDER; KAYE ANTHONY JAMES
摘要:The invention provides a novel series of tetracyclic quinoline and quinoxaline carboxamides, bis compounds in which two of the tetracyclic compounds are joined by a linker, and pharmaceutically-acceptable salts and N-oxides thereof, which have the ability to inhibit topoisomerase activity. The compounds are active in vitro and in vivo against tumour cells. Methods of synthesis and pharmaceutical compositions are also claimed.