CAS: 6180-61-6; 3-Phenoxy-1-Propanol

该化合物是一种有机化合物,其特征是附于丙醇脊椎的苯氧基组;一种无色的黄色液体,其气味优美,可溶于有机溶剂,但水溶性有限;分子结构包括一种含有苯氧替代成分的丙醇链,该链有助于其独特的化学特性;该化合物经常用于合成各种药品和农用化学化学品,因为它具有反应性和作为化学反应中间体的能力;此外,3-苯氧-1-丙醇表现出中度毒性,需要小心处理和使用期间采取适当的安全措施;其应用可能扩大到表面活性剂和其他特殊化学品的配制,突出其在工业过程中的多用途;与许多有机化合物一样,了解其在不同环境中的行为,包括其稳定性和反应能力,对于在实验室和工业环境中的有效利用至关重要.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号627-30-5 3-氯-1-丙醇 | CAS号108-95-2 苯酚 | CAS号1746-13-0 烯丙基苯基醚 | CAS号1141498-11-4 1-[3-(4-iodo-3-... | CAS号627-18-9 3-溴-1-丙醇 | CAS号7170-38-9 3-苯氧基丙酸 | CAS号504-63-2 1,3-丙二醇 | CAS号30263-10-6 diethoxy(methyl... | CAS号66003-76-7 二苯基三氟甲磺酸碘 | CAS号584-08-7 碳酸钾 | CAS号491-37-2 2,3-二氢苯并吡喃-4-酮 | CAS号22409-37-6 3-phenoxypropanamide | CAS号7170-38-9 3-苯氧基丙酸 | CAS号588-63-6 3-苯氧基溴丙烷 | CAS号122-59-8 苯氧乙酸 | CAS号3384-04-1 3-氯丙基苯基醚 | CAS号1776-09-6 3一溴一4一色满酮 | CAS号22409-91-2 3-苯氧基丙酸乙酯 | CAS号70659-93-7 3-fluoropropoxy... | CAS号7617-76-7 3-苯氧基丙-1-胺

合成工艺路线路线简述

  • 合成目标产物 3-Phenoxy-1-Propanol 主要起始原料 3-Bromo-1-Propanol And Phenol
  • (文献来源)合成步骤主要原料 3-Bromo-1-Propanol 和 Phenol
3-苯氧基丙基三氯硅烷置于potassium Fluoride,Potassium Hydrogencarbonate,双氧水体系中,用 四氢呋喃,甲醇,水 作为反应溶剂,化学反应 1.0H,反应生成 3-苯氧基-1-丙醇
参考文献:将硅烷自由基加成到烯烃上,然后氧化
标题:将硅烷自由基加成到烯烃上,然后氧化
摘要:使用三乙基硼烷作为引发剂,与二烯烃反应后,苯二甲基硅烷和三氯硅烷显示出有效的自由基氢化硅烷化反应.可以将三氯硅烷反应中的加合物氧化,以高收率得到醇.此两步过程导致烯烃的反马氏水合. 加成反应-醇-烯烃-自由基反应-硅烷
DOI:10.1055/s-0031-1289568

海关参考信息

专利信息


专利号:US-5753726-A
优先权日:1995-12-20
标 题:Synthesis of modified epoxy resins for cathodic electrodeposition with catalyst deactivation and diol modification
发明人:REUTER HARDY; JOUCK WALTER; OTT GUENTHER
权利人:BASF LACKE & FARBEN
摘要:Epoxy resins for preparing water-dispersible binders for cathodic electrodeposition coating materials, the epoxy resin being preparable by reacting a) polyepoxides having at least one glycidyl group per molecule b) and, optionally, up to 60% by weight, based on the overall epoxy resin reaction product, of aliphatic and/or alicyclic hydroxy compounds having preferably two or on average less than two hydroxyl groups per molecule and a molecular weight of less than 9000 g/mol, c) in the presence of a catalyst consisting of neutral metal salts, such as alkali metal salts and alkaline earth metal salts, zinc salts and nickel salts of tetrafluoroboric, tetrachloroboric, hexafluoro- antimonic,hexachloroantimonic,hexafluorophosphoric, perchlorate and periodic acid, and d) adding a deactivating agent which prevents the epoxy groups reacting further or effectively reduces the rate of such reaction as soon as the phenolic hydroxyl groups have already substantially reacted and at least 0.6% by weight of epoxy groups are still present, based on the overall weight of the epoxy resin reaction product.\\!

专利号:US-8815913-B2
优先权日:2006-12-06
标 题 :Metal-catalyzed copolymerization of imines and carbon monoxide as a route to synthesize polypeptides
发明人:SUN HUAILIN; ZHANG JIAN; LIU QIUHUA; YU LEI; ZHAO JIANGYU
权利人:SUN HUAILIN; ZHANG JIAN; LIU QIUHUA; YU LEI; ZHAO JIANGYU; UNIV NANKAI
摘要:Polypeptides of formula (I): n nwherein R 1 and R 2 are substituents independently selected from substituted and un-substituted alkyl groups and substituted and un-substituted aryl groups, and n is an integer greater than or equal to 2. Synthesis methods are also provided that do not use amino acids as starting materials, but instead employ imines and carbon monoxide as monomers that undergo transition metal-catalyzed alternating copolymerization to directly provide polypeptides using an acylcobalt catalyst with the following structural formula:n n nwherein R is selected from the group consisting of alkyl, phenyl, and substituted phenyl groups.

专利号:US-8858968-B2
优先权日:2005-12-05
标题 :Use of tyrosine-arginine dipeptide and niacinamide as substance P antagonist
发明人:POTIN ANTHONY
权利人:POTIN ANTHONY; OREAL
摘要:Use of the combination of the tyrosine-arginine dipeptide or derivatives thereof and of niacinamide as a substance P antagonist for treating red blotches on the skin, skin oedema and sensitive skin. Use of this combination for the preparation of a composition for use in treating disorders associated with an excess synthesis and/or release of substance P.

专利号:US-4652584-A
优先权日:1984-07-13
标 题 :Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
发明人:CARSON JOHN R
权利人:MCNEILAB INC
摘要:Phenoxypropanol derivatives having a 2-acetylenic moiety on the phenyl group thereof of the following formula (I): ##STR1## and their use as anti-hypertensives, e.g. in man. Also part of the invention are pharmaceutical compositions and intermediates used in the synthesis.

专利号:US-6797819-B1
优先权日:1998-06-11
标 题 :Alkaloids
发明人:SHAIR MATTHEW; WESTWOOD NICHOLAS; PELISH HENRY EFREM; KIRCHHAUSEN THOMAS; FENG YAN
权利人:HARVARD COLLEGE; CBR INST FOR BIOMED RES INC
摘要:The present invention provides novel alkaloid compounds and collections of these compounds, and provides methods for the synthesis of these compounds using biomimetic synthetic strategies. Additionally, the present invention provides pharmaceutical compositions and methods for treating disorders such as bacterial infections, proliferative diseases, and reproductive disorders, to name a few.

专利号:WO-2024040267-A2
优先权日:2022-08-19
标题 :Direct synthesis of n-(3-substituted-chroman-4-yl)-7h- pyrrolo[2,3-d]pyrimidin-4-amines and derivatives thereof
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合成参考文献


摘要:Hollmann, F., Science of Synthesis Knowledge Updates, (2021) 3, 437.
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