专利号:WO-2009056955-A1 优先权日:2007-10-30 标题 :Amine-bearing phospholipids (abps), their synthesis and use 发明人:ZUMBUEHL ANDREAS 权利人:UNIV BASEL; ZUMBUEHL ANDREAS 摘要:Disclosed herein are amine-bearing phospholipids (ABP). The ABPs display many properties and functionalities of naturally occurring phospholipids, but also new properties and functionalities, such as the ability to polymerize while maintaining structural integrity, that may supplement or expand the functionalities of naturally occurring phospholipids.
专利号:US-2011229556-A1 优先权日:2010-03-19 标 题:Lipid-coated polymer particles for immune stimulation 发明人:IRVINE DARRELL J; BERSHTEYN ANNA; MOON JAEHYUN 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:The invention provides delivery systems comprised of lipid coated polymer core particles, as well as compositions, methods of synthesis, and methods of use thereof. The particles can be used to carry antigen and adjuvant, resulting in enhanced immune responses.
参考文献:10.1007/s12035-019-01677-8 摘要:Lopez-Font I, Boix CP, Zetterberg H, Blennow K, Sáez-Valero J. Characterization of Cerebrospinal Fluid BACE1 Species. Mol Neurobiol. 2019 Dec;56(12):8603–16. doi: 10.1007/s12035-019-01677-8. 参考文献:10.1007/s00441-022-03580-6 摘要:Herbertz M, Harder S, Schlüter H, Lohr C, Dobler S. Na,K-ATPase α1 and β-subunits show distinct localizations in the nervous tissue of the large milkweed bug. Cell and Tissue Research. 2022 Mar 25;388(3):503–19. doi: 10.1007/s00441-022-03580-6.