CAS: 545-48-2; (3S,4Ar,6Ar,6Bs,8As,12As,14Ar,14Br)-8A-(Hydroxymethyl)-4,4,6A,6B,11,11,14B-Heptamethyl-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,14,14A,14B-Icosahydropicen-3-Ol

上下游产品

CAS号508-02-1 齐墩果酸 | CAS号107387-66-6 3β-benzoyloxy-2... | CAS号118800-83-2 18,28-cyclo-ole... | CAS号6153-31-7 Oleanolic acid ... | CAS号152487-59-7 tert-butyl(((4a... | CAS号77-52-1 熊果酸 | CAS号559-70-6 beta-香树精 | CAS号17990-42-0 3-氧代-12-烯-28-齐墩果酸

📜熊果酸置于lithium Aluminium Tetrahydride,水体系中,用 四氢呋喃 作为反应溶剂,化学反应 3.0H,以85%的收率获得产物高根二醇
参考文献:桦木醇,高根二醇和紫杉醇的氨基丙氧基衍生物的合成和抗肿瘤活性
标题:桦木醇,高根二醇和紫杉醇的氨基丙氧基衍生物的合成和抗肿瘤活性
摘要:桦木醇,高根二醇,紫杉醇和齐墩果三醇的氨基丙氧基衍生物已经通过三萜类化合物的羟基的氰乙基化以及随后的氰乙基片段的还原来合成.已发现 3β,28-Di-O-[3-(Aminopropoxy)]Lupa-20(29)-Ene 和 3β-O-Hydroxy-28-O-[3-(Aminopropoxy)]Olean-12-Ene对多种人类肿瘤细胞系具有高体外抗肿瘤活性.已经表明,氨基丙氧基片段是合成基于三萜类化合物的抗癌剂中的一种新的有前景的药效团.
DOI:10.1134/s1068162011030101

专利信息

专利号:US-9943544-B2
优先权日:2015-03-18
标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancer
发明人：BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
权利人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
摘要:The present invention is a process for bio synthesis of nano arsenic trioxide defined by its low toxicity, higher bio availability and nano particle size with the aid of buttermilk, goat urine, dolichos biflorous and other plant materials such as ginger, momordica charantia and musa paradisiaca . The invention is carried out in different steps involving purification of crude form of arsenic trioxide by boiling it with buttermilk, goat urine and extract of dolichos biflorous in subsequent steps, followed by the trituration of the bio purified arsenic trioxide with extracts of ginger and momordica charantia in subsequent steps and heating of the dry product obtained after trituration with musa paradisiaca resulting in the production of novel nano arsenic trioxide. The product is effective in the treatment of various diseases including different types of cancer in animals and humans. The product obtained through the process is less toxic with higher bio availability.

专利号:US-4908380-A
优先权日:1986-11-04
标题:Pharmaceutical compositions
发明人：BREWSTER ANDREW G; BROWN GEORGE R; SMITHERS MICHAEL J
权利人:ICI PLC
摘要:The invention concerns novel pharmaceutical compositions containing a 4(Z)-6-(2,4-diphenyl-1,3-dioxan-5-yl)-alkenoic acid which antagonizes one or more of the actions of thromboxane A2, together with a compound which inhibits the synthesis of thromboxane A2. The compositios are useful as medicines in treating a variety of diseases or medical conditions in which thromboxane A2 and/or other prostanoid contractile substances are involved.

专利号:US-4925869-A
优先权日:1986-11-04
标题 :Therapeutic agents
发明人：SMITHERS MICHAEL J
权利人:ICI PLC
摘要:The invention concerns novel therapeutic agents containing a (Z)-(2-alkoxyalkyl- or 2-aryloxyalkyl-4-phenyl-1,3-dioxan-5-yl)alkenoic acid, or a related tetrazole derivative, which antagonizes one or more of the actions of thromboxane A2, together with a compound which inhibits the synthesis of thromboxane A2. The compositions are useful as medicines in treating a variety of diseases or medical conditions in which thromboxane A2 and/or other prostanoid contractile substances are involved.

专利号:US-2016271177-A1
优先权日:2015-03-18
标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancer

专利号:EP-2897906-A1
优先权日:2012-09-20
标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancers

专利号:EP-2897906-B1
优先权日:2012-09-20
标题 :Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancers
发明人：BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
权利人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH