CAS: 50722-38-8; 3-Acetyldeoxynivalenol
该化合物是源自小麦和大麦等谷物作物中常见的真菌富氨酸甘蓝菌某些菌株生产的蛋白毒素,以对人类和动物的毒性作用著称;3-ADON的特点是其乙基结构,影响其生物活动和毒性;这种复合物的特性,如蛋白合成的强效抑制剂,导致不良的健康影响,包括恶心,呕吐和摄入时免疫抑制;极地溶剂中的溶解性以及各种环境条件下的稳定性,促使其长期存在受污染的食品;监管机构监测食品供应中因潜在健康风险而出现的3-亚丁二醇水平,并继续研究其行动机制及其对人和动物健康的影响;了解3-乙酰二氧氮基氮基甲醇的特性对于制定减轻其对粮食安全和公共健康的影响的战略至关重要.
- 英文名称3-Acetyldeoxynivalenol
- 中文名称3-乙酰脱氧瓜萎镰菌醇
- IUPAC名称(2S,3'R,5'R,5a'R,6'S,9a'R)-6'-hydroxy-5a'-(hydroxymethyl)-5',8'-dimethyl-7'-oxo-2',3',4',5',5a',6',7',9a'-octahydrospiro[oxirane-2,10'-[2,5]methanobenzo[b]oxepin]-3'-yl acetate
- 其它别名Spiro[2,5-methano-1-benzoxepin-10,2'-oxirane],trichothec-9-en-8-one deriv.; 3-Acetyldeoxynivalenol; 3a-Acetoxy-12,13-epoxytrichothec-9-en-8-one; DON 3-acetate; Dehydronivalenol monoacetate; Deoxynivalenol 3-acetate; Deoxynivalenol monoacetate; Monoacetyldeoxynivalenol
- CAS编号50722-38-8
- MFCD编号:MFCD28143209
- EINECS号:621-771-5
- FDA UNII编号:838JJ2425Y
- 分子式:C17H22O7分子量:338.35
- 产品CID: 1495522
- 产品分类分析化学 → 标准品 → 食品和化妆品标准品
物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS06;
注释: Skull and crossbones - 危险类别急性毒性 类别2(吸入)
急性毒性 类别2(经皮)
急性毒性 类别2(经口)
急性毒性 类别3(吸入)
急性毒性 类别3(经皮) - 警示词Danger(危险)
- 危险描述H330 |吸入致命.
H310 |皮肤接触致命.
H300 |吞咽致命.
H331 |吸入会中毒.
H311 |皮肤接触会中毒. - 防范说明P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311
- 危险等级6.1(a)
- UN编号UN 2811 6.1/PG 2
- 危险品标志T,Xn,F
- 包装等级I
- 安全声明36/37-45-26-16
- 危险类别码23/24/25-36-20/21/22-11
- WGK Germany3
欧盟法规
ECHA物质C&L通报上下游产品
trichodiene acetone acetic anhydride vomitoxin hydrate Deoxynivalenol triacetate deoxynivalenol-15-O-β-D-glucopyranoside 3α-acetyl-12,13-epoxy-7α-hydroxy-15-(trityloxy)trichothec-9-en-8-one vomitoxin hydrate合成工艺路线路线简述
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:CN-119391806-A
优先权日:2024-11-11
标题 :Method for identifying compound for inhibiting synthesis of vomitoxin of wheat stem rot pathogen
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Tebele SM, Gbashi S, Adebo O, Changwa R, Naidu K, Njobeh PB. Quantification of multi-mycotoxin in cereals (maize, maize porridge, sorghum and wheat) from Limpopo province of South Africa. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2020 Sep
8:1-17. doi: 10.1080/19440049.2020.1808715. Epub ahead of print. 36(4):353-360. doi: 10.1007/s12550-020-00401-z. Epub 2020 Jul 11. 104(8):2138-2143. doi: 10.1094/PDIS-01-20-0084-RE. Epub 2020 Jun 15.
331:108628. doi: 10.1016/j.ijfoodmicro.2020.108628. Epub 2020 Apr 13. 12(6):362. doi: 10.3390/toxins12060362.
合成参考文献
摘要:Shokuhin Eiseigaku Zasshi. Food Hygiene Journal., 15(261), 1974
摘要:Toxicon., 24(985), 1986 []
参考文献:10.1007/s10482-005-9045-7
摘要:Llorens A, Hinojo MJ, Mateo R, Medina A, Valle-Algarra FM, González-Jaén MT, Jiménez M. Variability and characterization of mycotoxin-producing Fusarium spp isolates by PCR-RFLP analysis of the IGS-rDNA region. Antonie Van Leeuwenhoek. 2006 Apr;89(3-4):465–78. doi: 10.1007/s10482-005-9045-7.
参考文献:10.1007/s12550-018-0318-1
摘要:Chilaka CA, De Boevre M, Atanda OO, De Saeger S. Stability of fumonisin B1, deoxynivalenol, zearalenone, and T-2 toxin during processing of traditional Nigerian beer and spices. Mycotoxin Res. 2018 Nov;34(4):229–39. doi: 10.1007/s12550-018-0318-1.
参考文献:10.1007/s11046-008-9127-y
摘要:Haratian M, Sharifnabi B, Alizadeh A, Safaie N. PCR analysis of the Tri13 gene to determine the genetic potential of Fusarium graminearum isolates from Iran to produce nivalenol and deoxynivalenol. Mycopathologia. 2008 Aug;166(2):109–16. doi: 10.1007/s11046-008-9127-y.
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