CAS: 4431-74-7; 3-Aminobenzene-1-Sulfonyl Chloride
该化合物是有机合成中的关键中间体,特别是在准备磺酰胺和其他含有磺酰氟的化合物方面,其反应性磺酰氯组能够高效衍生,使其对制药和农用化学应用具有价值.在元体位置上存在一个氨基生物组可提供更多功能化机会,在多步组合中提高其多功能性.该复合体的特点是在受控条件下高度纯度和稳定性,确保有可靠的反应性能.该化合物在混合反应和作为生物活性分子的构件方面非常有用,突出了其在工业和研究环境中的重要性.由于水分敏度和再活性,需要妥善处理.
- 英文名称3-Aminobenzene-1-Sulfonyl Chloride
- 中文名称3-氨基-苯磺酰氯
- IUPAC名称3-aminobenzenesulfonyl chloride
- 其它别名3-Amino-Benzenesulfonyl Chloride; Benzenesulfonyl Chloride, 3-Amino-
- CAS编号4431-74-7
- MFCD编号:MFCD18837125
- 分子式:C6H6ClNO2S分子量:191.64
- 产品CID: 1451428
- 产品分类有机原料 → 羧酸类化合物及衍生物 → 羧酸酰卤化物
MSDS等安全信息
上下游产品
3-nitrobenzene-1-sulfonyl fluoride N-(5-cyclohexyl-[1,3,4]oxadiazol-2-yl)-benzenesulfonamide3-amino-N-(5-cyclohexyl-[1,3,4]oxadiazol-2-yl)-benzenesulfonamide 2-(3-((R)-1-((S)-1-(3-aminophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxyphenyl)propyl)phenoxy)acetic acid合成工艺路线路线简述
📜3-硝基苯磺酰氟置于palladium On Carbon,氢气,溶剂黄146体系中,用 乙酸乙酯 作为反应溶剂,化学反应 3.0H,反应生成 3-氨基-苯磺酰氯
参考文献:Design,Synthesis,And Evaluation Of Cell Permeable Probes For Protein Kinases
标题:Design,Synthesis,And Evaluation Of Cell Permeable Probes For Protein Kinases
摘要:We Have Explored A Novel Molecular Framework With A Lysine Core To Prepare A Probe Library For Protein Kinases. Active Site-Directed Probes,Identified Through Screening Of The Library,Displayed Desirable Labelling Properties,Including Target Specificity,Good Linear Response To The Corresponding Enzymatic Activity And Cell Permeability. Finally,A Two-Stage Protocol Utilizing The Newly Developed Probe With An Immunoprecipitation Step Was Successfully Established To Monitor Intracellular Src Kinase Activity In Rige-V-Src Cells. (C) 2015 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tet.2015.10.053
专利信息
专利号:US-8633337-B2
优先权日:2010-05-14
标 题 :Method and synthesis
发明人：BRATHE ANDERS; OLSSON ANDREAS; THANING MIKKEL; BUGGE STEFFEN
权利人:BRATHE ANDERS; OLSSON ANDREAS; THANING MIKKEL; BUGGE STEFFEN; GE HEALTHCARE LTD
摘要:The present invention provides a method for the preparation of a radiolabeled guanidine derivative, in particular wherein the radiolabeled guanidine derivative is a positron emission tomography (PET) tracer. Certain intermediates useful in said method are also provided, as well as means for carrying out said method in an automated fashion. The method of the invention provides advantages over known methods for the preparation of radiolabeled guanidine derivatives.
专利号:US-10246411-B2
优先权日:2014-10-29
标 题:(Z)-3,4,5-trimethoxystyrylbenzenesulfonamides as potential anticancer agents
发明人：KAMAL AHMED; RASALA MAHESH; RATNA REDDY CHALLA; BHARATH KUMAR GAJJELA; SASTRY VISWESWARA; BASHA SHAIK ANVER; SANTHOSH REEDY VANGALA
权利人:COUNCIL SCIENT IND RES
摘要:This present invention relates to (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides of general formula A. The invention also provides the synthesis of (Z)-3,4,5-trimethoxystyrylbenzenesulfonamides useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考DOI号:10.1016/j.tet.2015.10.053
📝 需求与反馈
尽可能描述清楚需求与问题信息
