CAS: 41498-07-1; 4-Bromo-5-Nitrothiophene-2-Carbaldehyde

上下游产品

CAS号18791-75-8 4-溴-2-噻吩甲醛

📜4-溴-2-噻吩甲醛置于硫酸,Potassium Nitrate体系中,用 二氯甲烷 作为反应溶剂,化学反应 2.75H,以98.6%的收率获得产物4-溴-5-硝基-2-噻吩甲醛
参考文献: Novel Thiophene Amidines,Compositions Thereof,And Methods Of Treating Complement-Mediated Diseases And Conditions[fr] Nouvelles Amidines De Thiophene,Compositions De Ces Amidines Et Procede Pour Traiter Des Maladies Et Des Etats Medies Par Le Complement
标题: Novel Thiophene Amidines,Compositions Thereof,And Methods Of Treating Complement-Mediated Diseases And Conditions[fr] Nouvelles Amidines De Thiophene,Compositions De Ces Amidines Et Procede Pour Traiter Des Maladies Et Des Etats Medies Par Le Complement
摘要:揭示了一种治疗急性或慢性疾病症状的方法,该方法通过补体级联的经典途径介导,包括向需要此类治疗的哺乳动物施用化合物i的治疗有效量或其溶剂化合物,水合物或药用可接受盐;其中规范中定义了r1,R2,R3,R4和r7,Z为so或so2,Ar为本规范中定义的芳香族或杂环芳基.

专利信息

专利号:US-2008214565-A1
优先权日:2003-04-07
标 题:Oxazolidinone Derivatives as Antimicrobials
发明人：MEHTA ANITA; RUDRA SONALI; RAO AJJARAPU VENKATA SUBRAHMANYA RAJO; YADAV AJAY SINGH; RATTAN ASHOK
权利人:MEHTA ANITA; RUDRA SONALI; RAO AJJARAPU VENKATA SUBRAHMANYA RAJO; YADAV AJAY SINGH; RATTAN ASHOK
摘要:The present invention relates to certain substituted phenyl oxazolidinones of formula I and H and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

专利号:WO-2005082899-A1
优先权日:2004-01-28
标 题:Oxazolidinone derivatives as antimicrobials
发明人：SALMAN MOHAMMAD; BISWAJIT DAS; RUDRA SONALI; YADAV AJAY SINGH; RATTAN ASHOK
权利人:RANBAXY LAB LTD; SALMAN MOHAMMAD; BISWAJIT DAS; RUDRA SONALI; YADAV AJAY SINGH; RATTAN ASHOK
摘要:The present invention relates to certain substituted phenyl oxazolidinones of formula (I) and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing such compounds as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid-fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

专利号:WO-2004069816-A1
优先权日:2003-02-07
标 题:Oxazolidinone derivatives as antimicrobials
发明人：MEHTA ANITA; RUDRA SONALI; RAO AJJARAPU VENKATA SUBRAHMAN; YADAV AJAY SINGH; RATTAN ASHOK
权利人:RANBAXY LAB LTD; MEHTA ANITA; RUDRA SONALI; RAO AJJARAPU VENKATA SUBRAHMAN; YADAV AJAY SINGH; RATTAN ASHOK
摘要:The present invention relates to certain substituted phenyl oxazolidinones of the formula h wherein T is a ring and to the processes for the synthesis of the same. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bactericides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

专利号:US-9533996-B2
优先权日:2012-06-18
标 题 :Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6h)-ones
发明人：BRANSTETTER BRYAN; BREITENBUCHER JAMES; DYCK BRIAN; GOMEZ LAURENT; HUDSON ANDREW RICHARD; MARRONE TAMI JO; PETERS MARCO; VICKERS TROY; WEINHOUSE MICHAEL
权利人:DART NEUROSCIENCE (CAYMAN) LTD
摘要:Described herein are compounds of Formula I and Formula II, methods of their synthesis, compositions comprising the compounds, and use of the compounds and compositions in treating numerous diseases and disorders, including cognitive deficits associated with CNS diseases and disorders.