📜4-羟基苯磺酸置于氯化亚砜,N,N-二甲基甲酰胺体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.5H,反应生成 4-羟基苯磺酰氯 参考文献: Compounds As Crth2 Antagonist And Uses Thereof[fr] Composés En Tant Qu'Antagonistes De Crth2 Et Utilisations De Ceux-Ci 标题: Compounds As Crth2 Antagonist And Uses Thereof[fr] Composés En Tant Qu'Antagonistes De Crth2 Et Utilisations De Ceux-Ci 摘要:提供可用作crth2受体拮抗剂的化合物的化学式(i).化合物的化学式(i)可用于治疗和预防哮喘,过敏性鼻炎和特应性皮炎,以及其他由crth2受体介导的前列腺素d2(pgd2)引起的疾病.
专利号:US-10039844-B2 优先权日:2014-12-03 标 题 :Imaging tumor glycolysis by non-invasive measurement of pyruvate kinase M2 发明人:WITNEY TIMOTHY; JAMES MICHELLE L; GAMBHIR SANJIV S 权利人:UNIV LELAND STANFORD JUNIOR 摘要:A novel pyruvate kinase M2 (PKM2)-specific activator, [ 11 C]DASA-23 and derivatives thereof, and methods for their rapid synthesis are provided. The probes are particularly useful in methods for the non-invasive positron emission tomography (PET) detection and imaging of PKM2 expression in subcutaneous and orthotopic tumors. [ 11 C]DASA-23 cell uptake correlates with PKM2 protein expression in cultured tumor cells and orthotopic tumors are delineated from the surrounding normal brain tissue in vivo.
专利号:US-10246411-B2 优先权日:2014-10-29 标 题:(Z)-3,4,5-trimethoxystyrylbenzenesulfonamides as potential anticancer agents 发明人:KAMAL AHMED; RASALA MAHESH; RATNA REDDY CHALLA; BHARATH KUMAR GAJJELA; SASTRY VISWESWARA; BASHA SHAIK ANVER; SANTHOSH REEDY VANGALA 权利人:COUNCIL SCIENT IND RES 摘要:This present invention relates to (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides of general formula A. The invention also provides the synthesis of (Z)-3,4,5-trimethoxystyrylbenzenesulfonamides useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof.
专利号:CN-116102523-A 优先权日:2023-02-20 标题 :Synthesis method of bis (fluorosulfonyl) imide-1-methyl, propyl pyrrolidine salt
专利号:CN-116003457-B 优先权日:2023-02-06 标 题 :Synthesis method of tri (2, 2-trifluoroethyl) borate
专利号:ES-2501640-T3 优先权日:2009-06-30 标题:Benzenesulfonamide compounds, their method of synthesis and their use in medicine