CAS: 4025-67-6; 4-Hydroxybenzenesulfonyl Chloride

该化合物是一种全氟辛烷磺酸试剂,广泛用于有机合成,特别是用于将磺酰胺组引入苯丙酸化合物,其主要优点包括高活性,在温和条件下促成高效的全氟辛烷磺酸,以及选择苯丙基氢氧基组.该化合物在药品,染料和农用化学品中是一个多用途中间体,有助于合成磺酰胺和其他衍生物.其晶体形式确保了始终的纯度,在受控制条件下,其稳定性允许进行可靠的处理.该产品与一系列溶剂和试剂的兼容性进一步提高了其在多步骤合成途径中的效用.建议在冷干环境中妥善储存以保持最佳性能.

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CAS号825-90-1 4-羟基苯磺酸钠 | CAS号98-67-9 对羟基苯磺酸 | CAS号3077-65-4 4-(吗啉磺酰基)苯酚 | CAS号161356-05-4 对羟基苯磺酰苯胺 | CAS号15020-57-2 P-HYDROXY-N,N-D... | CAS号940951-88-2 N-(4-乙酰基苯基)-4-羟基苯磺酰胺 | CAS号96155-81-6 N-benzyl-4-hydr...

合成工艺路线路线简述

    📜4-羟基苯磺酸置于氯化亚砜,N,N-二甲基甲酰胺体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.5H,反应生成 4-羟基苯磺酰氯
    参考文献: Compounds As Crth2 Antagonist And Uses Thereof[fr] Composés En Tant Qu'Antagonistes De Crth2 Et Utilisations De Ceux-Ci
    标题: Compounds As Crth2 Antagonist And Uses Thereof[fr] Composés En Tant Qu'Antagonistes De Crth2 Et Utilisations De Ceux-Ci
    摘要:提供可用作crth2受体拮抗剂的化合物的化学式(i).化合物的化学式(i)可用于治疗和预防哮喘,过敏性鼻炎和特应性皮炎,以及其他由crth2受体介导的前列腺素d2(pgd2)引起的疾病.

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    专利信息


    专利号:US-10039844-B2
    优先权日:2014-12-03
    标 题 :Imaging tumor glycolysis by non-invasive measurement of pyruvate kinase M2
    发明人:WITNEY TIMOTHY; JAMES MICHELLE L; GAMBHIR SANJIV S
    权利人:UNIV LELAND STANFORD JUNIOR
    摘要:A novel pyruvate kinase M2 (PKM2)-specific activator, [ 11 C]DASA-23 and derivatives thereof, and methods for their rapid synthesis are provided. The probes are particularly useful in methods for the non-invasive positron emission tomography (PET) detection and imaging of PKM2 expression in subcutaneous and orthotopic tumors. [ 11 C]DASA-23 cell uptake correlates with PKM2 protein expression in cultured tumor cells and orthotopic tumors are delineated from the surrounding normal brain tissue in vivo.

    专利号:US-10246411-B2
    优先权日:2014-10-29
    标 题:(Z)-3,4,5-trimethoxystyrylbenzenesulfonamides as potential anticancer agents
    发明人:KAMAL AHMED; RASALA MAHESH; RATNA REDDY CHALLA; BHARATH KUMAR GAJJELA; SASTRY VISWESWARA; BASHA SHAIK ANVER; SANTHOSH REEDY VANGALA
    权利人:COUNCIL SCIENT IND RES
    摘要:This present invention relates to (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides of general formula A. The invention also provides the synthesis of (Z)-3,4,5-trimethoxystyrylbenzenesulfonamides useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof.

    专利号:CN-116102523-A
    优先权日:2023-02-20
    标题 :Synthesis method of bis (fluorosulfonyl) imide-1-methyl, propyl pyrrolidine salt

    专利号:CN-116003457-B
    优先权日:2023-02-06
    标 题 :Synthesis method of tri (2, 2-trifluoroethyl) borate

    专利号:ES-2501640-T3
    优先权日:2009-06-30
    标题:Benzenesulfonamide compounds, their method of synthesis and their use in medicine

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s00203-025-04260-z
    摘要:Nirusha K, Nagendra Prasad HS, Lohith TN, Saravanan P, Mallesha L, Anand AP. Exploration of piperazine-citral sulfonyl derivatives: antibacterial and in-silico studies against methicillin-resistant Staphylococcus aureus. Arch Microbiol. 2025 Feb 12;207(3):56. doi: 10.1007/s00203-025-04260-z.
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