CAS: 23725-05-5; (S)-2-((3S,4S)-3-Carboxy-5,6,7-Trihydroxy-1-Oxoisochroman-4-yl)Succinic Acid
该化合物是天然产生的有机化合物,主要见于大切布拉树(俗称haritaki)的果实,被归类为三叶类,以其潜在的健康利益而著称,包括抗氧化剂,抗炎和抗微生物特性;酸的化学结构是碳,氢和氧原子的复杂组合,有助于其生物活动;它经常在传统医学和草药疗法的背景下,特别是在Ayurvedic做法中进行研究;硫酸溶于水和有机溶剂中,可溶于水和有机溶剂,可适用于各种药品和营养素的应用;它在促进消化健康方面的作用及其对代谢过程的潜在影响,引起了科学研究的兴趣;
- 英文名称(S)-2-((3S,4S)-3-Carboxy-5,6,7-Trihydroxy-1-Oxoisochroman-4-yl)Succinic Acid
- 中文名称诃子次酸
- IUPAC名称(S)-2-((3S,4S)-3-carboxy-5,6,7-trihydroxy-1-oxoisochroman-4-yl)succinic acid
- 其它别名(2S)-2-[(3S)-3,4-Dihydro-3α-Carboxy-5,6,7-Trihydroxy-1-Oxo-1H-2-Benzopyran-4β-Yl]Butanedioic Acid; Butanedioic Acid,[(3S,4S)-3-Carboxy-3,4-Dihydro-5,6,7-Trihydroxy-1-Oxo-1H-2-Benzopyran-4-Yl]-,(2S)-; Chebulic Acid; Split Acid; Chebulic Acid(Sh); (2S)-[(3S,4S)-3-Carboxy-3,4-Dihydro-5,6,7-Trihydroxy-1-Oxo-1H-2-Benzopyran-4-Yl]Butanedioic Acid; (S)-2-((3S,4S)-3-Carboxy-5,6,7-Trihydroxy-1-Oxoisochroman-4-yl)Succinic Acid; (-)-Chebulic Acid
- CAS编号23725-05-5
- MFCD编号:MFCD09264641
- FDA UNII编号:G66Q7V3DPP
- 分子式:C14H12O11分子量:356.24
- 产品CID: 1179712
- 产品分类有机原料 → 羧酸类化合物及衍生物
物理性质
MSDS等安全信息
上下游产品
chebulagic acid合成工艺路线路线简述
📜Chebulagic Acid 以 水 用作溶剂,化学反应生成诃子次酸
参考文献:Absolute Configurations Of Chebulic,Chebulinic And Chebulagic Acid.
标题:Absolute Configurations Of Chebulic,Chebulinic And Chebulagic Acid.
摘要:鞭毛酸(3)的绝对构型通过其甲基衍生物(4)与一个苯甘草衍生物(11)的cd光谱比较确定.这个结果促成了鞭毛酸(1),鞭毛酸(2)和三羧酸三内酯(15)的绝对构型的确定.
Doi:10.1248/cpb.30.2655
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905122000-异丙醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-11547655-B2
优先权日:2017-08-02
标 题:Use of an extract of the pericarp of Nephelium lappaceum for hydrating the skin and/or mucous membranes
发明人：BONNET ISABELLE; CADAU SÉBASTIEN; DANOUS LOUIS; DERCEVILLE CHARLOTTE; LEOTY-OKOMBI SABRINA
权利人:BASF BEAUTY CARE SOLUTIONS FRANCE S A S
摘要:A subject of the present invention is the cosmetic use of a pericarp extract of the plant Nephelium lappaceum for maintaining and/or increasing the hydration and/or the barrier effect of the skin and/or of the mucous membranes. The pericarp extract increases involucrin synthesis and the hyaluronic acid content and the synthesis of ATP and of the taurine transporter TAUT. Another subject of the invention relates to a cosmetic care process comprising the topical application of the pericarp extract of N. lappaceum. Finally, a subject of the invention relates to the pericarp extract for use, in particular dermatological use, thereof in the treatment and/or prevention of pathological conditions caused by a state of abnormal dryness of the skin and/or of the mucous membranes.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Yoo HJ, Hong CO, Ha SK, Lee KW. Chebulic Acid Prevents Methylglyoxal-Induced Mitochondrial Dysfunction in INS-1 Pancreatic β-Cells. Antioxidants (Basel). 2020 Aug 20;9(9):E771. doi: 10.3390/antiox9090771. 45(5):1082-1089. Chinese. doi: 10.19540/j.cnki.cjcmm.20191221.301. 83(4):985-995. doi: 10.1021/acs.jnatprod.9b00877. Epub 2020 Mar 6. 18(2):132-141. doi: 10.2174/1570162X18666200129112509. 119(3):1125-1137. doi: 10.1007/s00436-019-06579-1. Epub 2020 Jan 6. 44(17):3738-3744. Chinese. doi: 10.19540/j.cnki.cjcmm.20190614.201. 42(8):1322-1331. doi: 10.1248/bpb.b19-00061. 38(6):1726-1740. doi: 10.1080/07391102.2019.1615002. Epub 2019 May 14. 28(2):555-562. doi: 10.1007/s10068-018-0477-z.
10: Vora J, Patel S, Sinha S, Sharma S, Srivastava A, Chhabria M, Shrivastava N. Molecular docking, QSAR and ADMET based mining of natural compounds against prime targets of HIV. J Biomol Struct Dyn. 2019 Jan;37(1):131-146. doi: 10.1080/07391102.2017.1420489. Epub 2018 Jan 7. 17(1):373. doi: 10.1186/s12906-017-1870-5.
12: Koo YC, Pyo MC, Nam MH, Hong CO, Yang SY, Lee KW. Chebulic acid prevents hepatic fibrosis induced by advanced glycation end-products in LX-2 cell by modulating Nrf2 translocation via ERK pathway. Toxicol In Vitro. 2016 Aug;34:8-15. doi: 10.1016/j.tiv.2016.03.013. Epub 2016 Mar 25.
合成参考文献
参考文献:10.3390/nu7105406
摘要:Olennikov DN, Kashchenko NI, Chirikova NK. In Vitro Bioaccessibility, Human Gut Microbiota Metabolites and Hepatoprotective Potential of Chebulic Ellagitannins: A Case of Padma Hepaten® Formulation. Nutrients. 2015 Oct 13;7(10):8456–77.
📝 需求与反馈
尽可能描述清楚需求与问题信息
