CAS: 15400-53-0; Ethyl 2-Amino-4-Hydroxypyrimidine-5-Carboxylate

该化合物是一种火水化合物衍生物,在制药和农用化学合成方面有很大的用途,其结构包括氨基和氢氧基功能组,加强了进一步衍生的回活动;乙基酯提高了有机溶剂的溶性,便利了净化和下游应用;该化合物是核分子,抗病毒剂和其他生物活性分子合成的多种中间体;在标准条件下,其稳定性确保了可靠的处理和储存;多个反应场所的存在允许有选择地进行修改,使得它对于在医药化学和材料科学研究中建立复杂的循环循环框架具有价值.

结构式图片

相似化合物

28485-17-8 4774-35-0 2913410-89-4

欧盟法规

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上下游产品

diguanidine carbonate diethyl 2-ethoxymethylenemalonate guanidine hydrogen carbonate guanidine nitrate 2-amino-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl 5,8-dihydro-3-methyl-5-oxo-8-(1-oxo-1-phenylpropan-2-yl)-2-phenylimidazo[1,2-a]pyrimidine-6-carboxylate 6-ethoxycarbonyl-2-(4-nitrophenyl)-8H-imidazolo[1,2-a]pyrimid-5-one a]pyrimidine-6-carboxylic acid ethyl ester5-hydroxy-2-(4-methoxy-phenyl)-imidazo[1,2-a]pyrimidine-6-carboxylic acid ethyl ester

合成工艺路线路线简述

    📜胍,乙氧基甲叉丙二酸二乙酯置于sodium Ethanolate体系中,用 乙醇 用作溶剂,化学反应 6.0H,以85.02%的收率获得2-氨基-5-乙氧羰基-4-羟基嘧啶
    参考文献:2-(2-取代-4-羟基嘧啶-5-甲酰胺基)乙酸类化合物及其制备方法与用途
    标题:2-(2-取代-4-羟基嘧啶-5-甲酰胺基)乙酸类化合物及其制备方法与用途
    摘要:本发明公开了具有式ⅰ结构的一类2‑(2‑取代‑4‑羟基嘧啶‑5‑甲酰胺基)乙酸类化合物及其药学上可接受的盐.本发明还公开了上述化合物的制备方法,并同时公开了以式ⅰ化合物或其药学上可接受的盐作为活性有效成分的药物组合物,以及它们作为phd抑制剂,在治疗因红细胞生成素下降或不足而引起的贫血,特别是治疗肾性贫血方面的应用.

    海关参考信息

    专利信息


    专利号:US-11137242-B2
    优先权日:2016-06-01
    标 题:Conductive fiber comprising metal nanobelt and carbon nanomaterial composite, method for producing conductive fiber, fibrous strain sensor, and method for producing fibrous strain sensor
    发明人:HAN JOONG TARK; LEE GEON WOONG; SEO SEON HEE; JANG JEONG IN; JEONG SEUNG YOL; JEONG HEE JIN
    权利人:KERI KOREA ELECTROTECHNOLOGY RES INST
    摘要:A conductive fiber including a metal-nanobelt-carbon-nanomaterial composite. A manufacturing method thereof includes preparing a composite including a carbon nanomaterial and metal nanobelts and manufacturing a conductive fiber by mixing the composite with a polymer. A fibrous strain sensor and a manufacturing method thereof are also provided. Thereby, a conductive fiber including a metal-nanobelt-carbon-nanomaterial composite, which is able to increase conductivity of the conductive fiber through synthesis of metal nanobelts enabling area contact and to exhibit good contact between the carbon nanomaterial and the metal nanobelts due to formation of the metal nanobelts on the surface of the carbon nanomaterial and superior dispersion uniformity, and a fibrous strain sensor including the conductive fiber can be obtained. The conductive fiber can be effectively applied to a strain sensor based on a principle by which resistance drastically increases with an increase in a distance between metal nanobelts aligned in a fiber direction upon tensile strain of metal nanobelts enabling area contact.

    专利号:CN-114716961-B
    优先权日:2022-05-04
    标题:A kind of self-complementary quadruple hydrogen bond supramolecular hot melt adhesive and its synthesis method

    专利号:CN-114716961-A
    优先权日:2022-05-04
    标 题 :A kind of self-complementary quadruple hydrogen bond supramolecular hot melt adhesive and its synthesis method

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:S55 | ZINC15PHARMA | Pharmaceuticals from ZINC15 | DOI:10.5281/zenodo.3247749
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