CAS: 123583-37-9; Peptide Yy (3-36) (Human)

该化合物是内生浸泡激素Peptide YY(PYY)的生物活性碎片,在调节胃食欲和能量软化方面发挥着关键作用.34-氨酸丙酸酯有选择地与Y2受体结合,抑制食物摄取和调节胃肠运动.它的抽调形式PY(3-36),与全长浸泡相比,其陈代谢稳定性和受体特性有所增强.在代谢研究中广泛使用,它成为研究讽刺信号,肥胖机制以及潜在治疗应用的宝贵工具.产品在严格的质量控制下合成,以确保高纯度和生物活性,使其适合体外和活性研究.

结构式图片

MSDS等安全信息

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:CN-115515937-A
    优先权日:2020-05-08
    标 题:Dimers for the synthesis of peptidomimetics

    专利号:CN-114126619-B
    优先权日:2019-05-09
    标 题:Compounds used in the synthesis of peptide mimetics

    专利号:CN-114126619-A
    优先权日:2019-05-09
    标题 :Compounds for the synthesis of peptidomimetics

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1210/en.2004-0342
    摘要:Coll AP, Challis BG, O'Rahilly S. Peptide YY3-36 and satiety: clarity or confusion Endocrinology. 2004 Jun;145(6):2582–4. doi: 10.1210/en.2004-0342.
    参考文献:10.1038/sj.ijo.0802646
    摘要:Martin NM, Small CJ, Sajedi A, Patterson M, Ghatei MA, Bloom SR. Pre-obese and obese agouti mice are sensitive to the anorectic effects of peptide YY(3-36) but resistant to ghrelin. Int J Obes Relat Metab Disord. 2004 Jul;28(7):886–93. doi: 10.1038/sj.ijo.0802646.
    参考文献:10.1381/096089206777346619
    摘要:Ballantyne GH. Peptide YY(1-36) and Peptide YY(3-36): Part II. Changes after Gastrointestinal Surgery and Bariatric Surgery: Part I. Distribution, Release and Actions appeared in the last issue (May 2006). Obesity Surgery. 2006 Jun 01;16(6):795–803. doi: 10.1381/096089206777346619.
    参考文献:10.1016/j.mce.2006.04.026
    摘要:Fernandez-Fernandez R, Martini AC, Navarro VM, Castellano JM, Dieguez C, Aguilar E, Pinilla L, Tena-Sempere M. Novel signals for the integration of energy balance and reproduction. Mol Cell Endocrinol. 2006 Jul 25;254-255():127–32. doi: 10.1016/j.mce.2006.04.026.
    参考文献:10.1016/j.fertnstert.2005.09.065
    摘要:Budak E, Fernández Sánchez M, Bellver J, Cerveró A, Simón C, Pellicer A. Interactions of the hormones leptin, ghrelin, adiponectin, resistin, and PYY3-36 with the reproductive system. Fertil Steril. 2006 Jun;85(6):1563–81. doi: 10.1016/j.fertnstert.2005.09.065.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知