CAS: 1159600-41-5; (1,1-Dioxidothiomorpholino)(6-((3-(4-Fluorophenyl)-5-Methylisoxazol-4-yl)Methoxy)Pyridin-3-yl)Methanone

上下游产品

6-[3-(4-Fluoro-Phenyl)-5-Methyl-Isoxazol-4-Ylmethoxy]-Nicotinic Acid 1159600-32-4
6-[3-(4-Fluoro-Phenyl)-5-Methyl-Isoxazol-4-Ylmethoxy]-Nicotinic Acid Methyl Ester 1159600-30-2
6-[3-(4-Fluoro-Phenyl)-5-Methyl-Isoxazol-4-Ylmethoxy]-Nicotinonitrile 1431329-33-7
3-(4-氟苯基)-5-甲基-4-异噁唑甲醇 [3-(4-Fluorophenyl)-5-Methylisoxazol-4-Yl]Methanol 1018297-63-6
3-(4-氟苯基)-5-甲基-4-异恶唑羧酸 3-(4-Fluorophenyl)-5-Methylisoxazole-4-Carboxylic Acid 1736-21-6
3-(4-氟苯基)-5-甲基异恶唑-4-羧酸乙酯 3-(4-Fluorophenyl)-5-Methylisoxazole-4-Carboxylic Acid Ethyl Ester 954230-39-8

📜6-氯-3-氰基吡啶置于sodium Hydride,三乙胺,Methanaminium,N-[(Dimethylamino)(3H-1,2,3-Triazolo[4,5-B]Pyridin-3-Yloxy)Methylene]-N-Methyl-,Hexafluorophosphate(1-),Sodium Hydroxide体系中,用 四氢呋喃,乙醇,水,N,N-二甲基甲酰胺 用作溶剂,化学反应生成巴米沙尼
参考文献: Novel Gamma Aminobutyric Acid Type A Receptor Modulators For Mood Disorders[fr] Nouveaux Modulateurs Du Récepteur De L'Acide Gamma-Aminobutyrique De Type A Destinés Aux Troubles De L'Humeur
标题: Novel Gamma Aminobutyric Acid Type A Receptor Modulators For Mood Disorders[fr] Nouveaux Modulateurs Du Récepteur De L'Acide Gamma-Aminobutyrique De Type A Destinés Aux Troubles De L'Humeur

专利信息

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-3959322-A
优先权日:1960-09-22
标 题:Synthesis of 13-alkyl-gon-4-ones
发明人：HUGHES GORDON ALAN; SMITH HERCHEL
权利人:SMITH HERCHEL
摘要:The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.

专利号:US-6229055-B1
优先权日:1996-04-12
标题 :Synthesis of fluorinated xanthene derivatives
发明人：KLAUBERT DIETER H; GEE KYLE R
权利人:MOLECULAR PROBES INC
摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.

专利号:US-8188113-B2
优先权日:2006-09-14
标 题 :Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C; DECIPHERA PHARMACEUTICALS INC
摘要:The present invention relates to novel dihydropyridopyrimidinyl, dihydronaphthyridinyl, and related compounds which are kinase inhibitors and modulator useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:US-7417142-B2
优先权日:2002-03-28
标 题:Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same
发明人：ZHANG X PETER; CHEN YING; GAO GUANG-YAO
权利人:UNIV TENNESSEE RES FOUNDATION
摘要:Novel methods of synthesizing heteroatom-containing chiral porphyrins and chiral metalloporphyrins and the novel chiral porphyrins and chiral metalloporphyrins themselves are disclosed. Metal complexes of the chiral porphyrins are prepared in high yields and shown to be active catalysts for highly enantioselective and diastereoselective cyclopropanation, aziridination, and epoxidation of alkenes under a practical one-pot protocol.

专利号:US-7722851-B2
优先权日:2001-12-10
标题 :Bulk synthesis of carbon nanotubes from metallic and ethynyl compounds
发明人：KELLER TEDDY M; QADRI SYED B
权利人:US NAVY
摘要:A process of making carbon nanotubes comprising the steps of: providing a precursor composition comprising at least one metallic compound and at least one organic compound; wherein the organic compound is selected from the group consisting of an ethynyl compound, a metal-ethynyl complex, and combinations thereof; wherein the precursor composition is a liquid or solid at room temperature; and heating the precursor composition under conditions effective to produce carbon nanotubes. A carbon nanotube composition comprising carbon nanotubes and a metal component selected from the group consisting of metal nanoparticles and elemental metal; wherein the carbon nanotube composition is rigid.