CAS: 102831-07-2; 2-Azido-1-(1,3-Benzodioxol-5-yl)Ethanone

上下游产品

CAS号40288-65-1 1-(1,3-苯并氧)2-溴乙酮 | CAS号3162-29-6 3',4'-(亚甲基二氧)苯乙酮 | CAS号38061-34-6 2-氨基-1-苯并[1,3]二...

📜3,4-亚甲二氧苯乙酮置于n-溴代丁二酰亚胺(Nbs),Sodium Azide,对甲苯磺酸体系中,用 二甲基亚砜,乙腈 用作溶剂,化学反应生成2-叠氮-1-苯并二氧戊环-5-乙酮
参考文献:Antimycobacterial Natural Products: Synthesis And Preliminary Biological Evaluation Of The Oxazole-Containing Alkaloid Texaline
标题:Antimycobacterial Natural Products: Synthesis And Preliminary Biological Evaluation Of The Oxazole-Containing Alkaloid Texaline
摘要:Texaline,An Antimycobacterial Oxazole-Containing Alkaloid Previously Isolated From Amyris Texana And A. Elemifera,And Related Compounds Have Been Synthesized In Order To Explore Aspects Of The Structure-Anti Tuberculosis Activity Relationship. While Texaline Was Found To Be Inactive In Our Assays,Simpler Diaryloxazoles Were More Active Whilst Also Exhibiting Modest Toxic Selectivity,Leading To Their Identification As Potential Lead Compounds. (C) 2005 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2005.08.119

专利信息

专利号:WO-2010039911-A1
优先权日:2008-10-01
标题 :Calcilytic compounds
发明人：JEONG JAE U; MARQUIS ROBERT W JR
权利人:GLAXOSMITHKLINE LLC; JEONG JAE U; MARQUIS ROBERT W JR
摘要:Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.