CAS: 848784-85-0; (3β,4α)-3-[(O-6-Deoxy-α-L-Mannopyranosyl-(1→2)-O-[β-D-Glucopyranosyl-(1→4)]-α-L-Arabinopyranosyl)Oxy]-23-Hydroxylup-20(29)-En-28-Oic Acid

• 英文名称(3β,4α)-3-[(O-6-Deoxy-α-L-Mannopyranosyl-(1→2)-O-[β-D-Glucopyranosyl-(1→4)]-α-L-Arabinopyranosyl)Oxy]-23-Hydroxylup-20(29)-En-28-Oic Acid
• 中文名称白头翁皂苷D
• IUPAC名称(1R,3aS,5aR,5bR,7aR,8R,9S,11aR,11bR,13aR,13bR)-9-(((2S,3R,4S,5S)-4-hydroxy-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-(prop-1-en-2-yl)icosahydro-3aH-cyclopenta[a]chrysene-3a-carboxylic acid
• 其它别名Pulsatilla Saponin D; Lup-20(29)-En-28-Oic Acid; Lup-20(29)-En-28-Oic Acid,; Lup-20(29)-En-28-Oic Acid,3-[(O-6-Deoxy-Alpha-L-Mannopyranosyl-(1→2)-O-[beta-D-Glucopyranosyl-(1→4)]-Alpha-L-Arabinopyranosyl)Oxy]-23-Hydroxy-, (3Beta,4Alpha)- (9Ci); Lup-20(29)-En-28-Oic Acid,3-[(O-6-Deoxy-Alpha-L-Mannopyranosyl-(1→2)-O-[beta-D-Glucopyranosyl-(1→4)]-Alpha-L-Arabinopyranosyl)Oxy]-23-Hydroxy-, (3Beta,4Alpha)- (9Ci); 23-Hydroxyllup-20(29)-En-28-Oicacid,3-O--D-Glucopyranosyl(1→4)[-L-Rhamnopyranosyl)(1→2)--L-Arabinopyranoside]; Pulchinenoside D; Lup-20(29)-En-28-Oic Acid,3-O-[-L-Rhamnopyranosyl-(12)-[-D-Glucopyranosyl-(14)]--L-Arabinopyranoside]; Lup-20(29)-En-28-Oic Acid, 3-[(O-6-Deoxy-α-L-Mannopyranosyl-(1→2)-O-[β-D-Glucopyranosyl-(1→4)]-α-L-Arabinopyranosyl)Oxy]-23-Hydroxy-, (3β,4α)-
• CAS编号848784-85-0
• MFCD编号:MFCD28124364
• 分子式:C47H76O17分子量:913.11
• 产品CID: 1839828
• 产品分类生物化工 → 植物提取物

• 相似结构搜索
• InChIKey: XFCSYQCYIKSNBB-WZGBEVHGSA-N
• InChI=1S/C47H76O17/c1-21(2)23-10-15-47(42(57)58)17-16-45(6)24(30(23)47)8-9-28-43(4)13-12-29(44(5,20-49)27(43)11-14-46(28,45)7)63-41-38(64-39-36(55)34(53)31(50)22(3)60-39)
• 计算化学: 氢键受体数*氢键供体数*可旋转键数*

物理性质

• 熔点250-252 °C
• 沸点994.3±65.0 °C at 760 mmHg
• 闪点284.3±27.8 °C
• 密度1.4±0.1 g/cm3
• PSA:274.75
• LogP:5.66
• 折射率1.615
• 蒸汽压0.0±0.6 mmHg at 25°C
• 外观形态白色晶体
• 储存条件2-8°C，密封保存，干燥环境，避光
• 产品应用该化合物是抑制了肿瘤细胞细胞性肺癌BEL-7402细胞的外细胞基质降解,并减少肝细胞细胞细胞肺癌的入侵和转移潜力,特别是当与SORAFENIB结合使用时;通过降低对低调低降调低低低氧可感应系数-1Α(HIF-1Α)和血管内宫内生长系数(VEGF)的表达方式,表现出抗诱变效应;通过调节AKT/TAR信号路径,在结肠癌细胞中诱发出骨硬化症;通过大幅降低PI3K,AKT,MTOR和P70S6K蛋白,从而抑制A549肺癌细胞的传播;通过大大降低PITK,MAT,P70-S6K蛋白;在A5 49细胞中促进人口传染,将人口比例提高到72.6和40毫克/L下移至760%.

MSDS等安全信息

• 警示词Danger
• 危险描述H301+H311+H331-
• 防范说明P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P361+P364-P403+P233-P405-P501-

合成工艺路线路线简述

海关参考信息

• 2901210000-乙烯
  2901220000-丙烯
  2905122000-异丙醇
  2905310000-1,2-乙二醇
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管