CAS: 621-83-0; Benzylthiourea

该化合物是一种有机化合物,其特征是存在一个附于苯甲基(苯基)的硫尿素功能组,该化合物一般是白色的脱白晶状固体,在乙醇和二甲基硫氧化物等极地有机溶剂中可溶解,但水溶性有限.N-(苯基)硫尿素表现出硫尿的典型特性,包括形成氢联结和参加各种化学反应的能力,例如核循环替代和与金属离子的协调.该化合物经常用于有机合成,并在各种化学反应中用作试剂,包括形成异硫氰酸.此外,该化合物可能展示生物活动,从而引起对药用化学和药理学的兴趣.在处理该物质时,应当采取安全防范措施,因为接触该物质可能会对健康造成危害.

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欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

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CAS号622-78-6 异硫氰酸苄酯 | CAS号4921-91-9 Benzamide,N-[[(... | CAS号3287-99-8 苄胺盐酸盐 | CAS号333-20-0 硫氰酸钾 | CAS号100-46-9 苄胺 | CAS号74734-11-5 1-(甲基二硫代羰基)咪唑 | CAS号115983-16-9 N-benzyl-N'-(2-... | CAS号7664-41-7 氨 | CAS号108-88-3 甲苯 | CAS号74-89-5 氨基甲烷 | CAS号538-32-9 苄脲 | CAS号3649-39-6 3-苄基次黄嘌呤 | CAS号25709-42-6 1,3-Dibenzylgua... | CAS号6343-54-0 N-苯甲基甲酰胺 | CAS号15087-95-3 ETHYL 2-(BENZYL... | CAS号1208-14-6 4(1H)-Pyrimidin... | CAS号68695-62-5 N-苄基-S-甲基异硫脲

合成工艺路线路线简述

    📜N-(Benzyl)Benzotriazole-1-Carboximidamide置于硫化氢体系中,用 四氢呋喃 作为反应溶剂,化学反应 1.0H,以76%的收率获得产物n-苄基硫脲
    参考文献:Synthesis Of Mono-And N,N-Disubstituted Thioureas And N-Acylthioureas
    标题:Synthesis Of Mono-And N,N-Disubstituted Thioureas And N-Acylthioureas
    摘要:由 1-氰基苯并三唑(1)和硫化氢制备的 1-苯并三唑-1-硫代甲酰胺(2)与胺反应反应生成硫脲类化合物 3A-E.(Benzotriazol-1-yl)Carboximidamides 4A-D,F-J 和 Acyl-5A-F,I-K 或 Arylaminocarbonyl-5G,H (Benzotriazol-1-yl)Carboximidamides 与硫化氢反应,分别得到相应的硫脲类化合物 3A-D,F-J,以及 N-酰基硫脲类化合物 6A-F,I-K 或 N-氨基甲酰基硫脲类化合物 6G,H.
    DOI:10.1055/s-2004-829127

    海关参考信息

    专利信息


    专利号:US-2008004415-A1
    优先权日:2004-05-03
    标题 :Non-linear optically active molecules, their synthesis, and use
    发明人:MCGINNISS VINCENT D; RISSER STEVEN M; DROTLEFF ELIZABETH; JIANG EDWARD; SPAHR KEVIN B
    权利人:OPTIMER PHOTONICS INC
    摘要:In one aspect, the present invention provides a hyperpolarizable organic chromophore. The chromophore is a nonlinear optically active compound that includes a Ï€-donor conjugated to a Ï€-acceptor through a Ï€-electron conjugated bridge. In other aspects of the invention, donor structures and acceptor structures are provided. In another aspect of the invention, a chromophore-containing polymer is provided. In one embodiment, the chromophore is physically incorporated into the polymer to provide a composite. In another embodiment, the chromophore is covalently bonded to the polymer, either as a side chain polymer or through crosslinking into the polymer. In other aspects, the present invention also provides a method for making the chromophore, a method for making the chromophore-containing polymer, and methods for using the chromophore and chromophore-containing polymer.

    专利号:US-2012059163-A1
    优先权日:2005-04-28
    标题 :Non-linear opticaly active molecules, their synthesis, and use
    发明人:MCGINNISS VINCENT D; RISSER STEVEN M; DROTLEFF ELIZABETH; JIANG EDWARD; SPAHR KEVIN B
    权利人:MCGINNISS VINCENT D; RISSER STEVEN M; DROTLEFF ELIZABETH; JIANG EDWARD; SPAHR KEVIN B; OPTIMER PHOTONICS INC
    摘要:In one aspect, the present invention provides a hyperpolarizable organic chromophore. The chromophore is a nonlinear optically active compound that includes a Ï€-donor conjugated to a Ï€-acceptor through a Ï€-electron conjugated bridge. In other aspects of the invention, donor structures and acceptor structures are provided. In another aspect of the invention, a chromophore-containing polymer is provided. In one embodiment, the chromophore is physically incorporated into the polymer to provide a composite. In another embodiment, the chromophore is covalently bonded to the polymer, either as a side chain polymer or through crosslinking into the polymer. In other aspects, the present invention also provides a method for making the chromophore, a method for making the chromophore-containing polymer, and methods for using the chromophore and chromophore-containing polymer.

    专利号:US-2899426-A
    优先权日:
    标题 :Synthesis of l

    专利号:CN-106674128-A
    优先权日:2016-12-31
    标题 :A class of licochalcone A thiouracil derivatives with anti-tumor activity and its synthesis method

    专利号:CN-107235916-A
    优先权日:2016-12-31
    标题:A kind of licochalcone A thiouracil derivative with antitumor activity and its synthesis method

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Koutentis, P. A.; Ioannidou, H. A., Science of Synthesis Knowledge Updates, (2010) 1, 287.
    摘要:Chebanov, V. A.; Gorobets, N. Yu.; Sedash, Yu. V., Science of Synthesis: Multicomponent Reactions, (2013) 1, 57.
    摘要:Wan, J.-P., Science of Synthesis: Multicomponent Reactions, (2013) 2, 378.
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