CAS: 531-59-9; 7-Methoxy-2H-Chromen-2-One

上下游产品

CAS号93-35-6 伞形花内酯； 7-羟基香豆素 | CAS号77-78-1 硫酸二甲酯 | CAS号74-88-4 碘甲烷 | CAS号150-19-6 3-甲氧基苯酚 | CAS号623-47-2 丙炔酸乙酯 | CAS号673-22-3 2-羟基-4-甲氧基苯甲醛 | CAS号4279-77-0 3-oxo-3-phenyls... | CAS号141-32-2 丙烯酸丁酯(BA) | CAS号108530-10-5 三氟甲磺酸2-氧代-2H-色满-7-基酯 | CAS号50551-61-6 6-甲氧基苯并呋喃-2-羧酸 | CAS号20921-02-2 7-methoxy-3,4-d... | CAS号93-35-6 伞形花内酯； 7-羟基香豆素 | CAS号2555-28-4 7-甲氧基-4-甲基香豆素 | CAS号139386-27-9 (E)-3-(2-羟基-4-甲... | CAS号15399-67-4 2-(2-aminopropa... | CAS号17598-02-6 7-甲氧基-2,2-二甲基-3-色烯 | CAS号11037-15-3 2-Isopropenyl-7... | CAS号2555-22-8 7-Methoxy-3-phe...

📜反式-4-甲氧基肉桂酸置于萘-1,4-二腈,氧气体系中,用 水,乙腈 作为反应溶剂,化学反应 6.0H,以80%的收率获得产物7-甲氧基香豆素
参考文献:单电子转移引发取代肉桂酸到相应香豆素的光环化
标题:单电子转移引发取代肉桂酸到相应香豆素的光环化
摘要:已经报道了通过单电子转移过程将取代的肉桂酸有效的光环化为相应的香豆素.已经讨论了一种可能的机制.
DOI:10.1016/s0040-4039(00)84914-X

专利信息

专利号:WO-2017137895-A1
优先权日:2016-02-09
标题 :New dendrimeric pyrrolidines, their synthesis and medical use
发明人：CARDONA FRANCESCA; PARMEGGIANI CAMILLA; MATASSINI CAMILLA; GOTI ANDREA; MORRONE AMELIA; CATARZI SERENA; D'ADAMIO GIAMPIERO
权利人:UNIVERSITA' DEGLI STUDI DI FIRENZE; AZIENDA OSPEDALIERO UNIV MEYER
摘要:The subject-matter of the present invention relates to the synthesis of new dendrimeric molecules based on polyhydroxylated pyrrolidines obtained by means of Click Chemistry reactions. The proposed molecules inhibit the enzymes N-acetylgalactosamine-6-sulfatase (GALNS), iduronate-2-sulfatase (IDS), a-mannosidase and β-glucosidase, deficient in lysosomal storage diseases. The presentation of multivalent iminosugars on a scaffold is a prerequisite for the inhibitory activity as the corresponding monomers are not active. The inhibitory activity reported is the basis for the development of the first-ASSC pharmacological chaperones proposed for the treatment of the above mentioned pathologies. Formula (I)

专利号:US-5419966-A
优先权日:1991-06-10
标 题 :Solid support for synthesis of 3'-tailed oligonucleotides
发明人：REED MICHAEL W; MEYER JR RICH B; PETRIE CHARLES R; TABONE JOHN C
权利人:MICROPROBE CORP
摘要:A solid support for oligonucleotide synthesis has the structure where CPG represents a controlled pore glass matrix, the wavy line represents a carbon chain covalently linking the NH group with the controlled pore glass matrix, X is 2,2'-dimethoxytrityl or H, and R is alkyl, aryl, arylalkyl, heteroalkyl, or heteroaryl. The dimethoxytrityl group is removed from the solid support by treatment with acid, and the oligonucleotide is built, step-by-step in a conventional synthesizer after attachment of the 3' end of the first oligonucleotide unit to the hydroxyl function connected to the R group.

专利号:WO-9318787-A1
优先权日:1992-03-25
标 题 :Trans-sialidase and methods of use and making thereof
发明人：NUSSENZWEIG VICTOR; SCHENKMAN SERGIO; EICHINGER DAN; VANDEKERCKHOVE FLIP
权利人:UNIV NEW YORK
摘要:Polypeptides are provided having trans-sialidase enzymatic activity in substantially pure form, nucleic acids coding therefor, antibodies specific for such polypeptides, processes for producing the enzyme and methods of use of the enzyme, in particular for the synthesis of sialyl α(2â†?3)-linked saccharides, glycoproteins and glycolipids. Such enzymes are isolatable as nucleic acid or amino acid sequences from parasites of the genus Trypanosoma.

专利号:WO-2005040371-A1
优先权日:2003-10-29
标题 :Engineered enzymes and their use for synthesis of thioglycosides
发明人：WITHERS STEPHEN G; JAHN MICHAEL
权利人:UNIV BRITISH COLUMBIA; WITHERS STEPHEN G; JAHN MICHAEL
摘要:Mutant glycosidases that are the subject of this invention (Fig. 1 D) have both the amino acids in the active site that serve as the acid, base, or acid/base catalyst, and the amino acid in the active site that serves as the catalytic nucleophile converted to some other amino acid (for example to a simple alkyl, as in alanine, or H, as in glycine) different from the wild-type amino acid. These double mutant enzymes, acting in the fashion of a scaffold, can catalyze the reaction of a thiosugar acceptor and a glycosyl donor (that has a good leaving group in the 1-position) to form a thioglycoside. The 'thioglycosynthases' represent a novel class of mutant enzymes and represent a first aspect of the invention. Thioglycosynthases can be used in accordance with the method of the invention to couple a thiosugar acceptor and an activated donor to form a thioglycoside. By selection of the donor and acceptor species, as well as the specific enzyme employed, thioglycosides of different structure and stereochemistry can be obtained.

专利号:US-6150403-A
优先权日:1997-10-14
标 题 :Topical compositions for regulating the oily/shiny appearance of skin
发明人：BIEDERMANN KIMBERLY A; SCHUBERT HARRY L; PARRAN JR JOHN J
权利人:PROCTER & GAMBLE
摘要:The present invention relates to methods for inhibiting sebaceous gland activity in mammalian skin comprising administration of a topical composition comprising dehydroacetic acid or pharmaceutically acceptable salts thereof, and a dermatologically-acceptable carrier. The present invention also relates to methods and topical compositions further comprising agents which regulate the oily and/or shiny appearance of skin, and agents which treat acne and related skin disorders in mammalian skin and scalp. Methods of reducing sebum synthesis with the use of dehydroacetic acid, methods of regulating the oily and/or shiny appearance of skin, and methods of treating acne and other skin disorders are also encompassed by the present invention.

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人：NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.