CAS: 52663-69-1; 2,2',3,4,4',5',6-Heptachloro-1,1'-Biphenyl

该化合物是一种氯化双苯衍生物,以其高热稳定性和化学惰性而著称,其独特的结构对溶剂,紫外辐射和环境退化具有极强的抗药性,因此适合各种工业应用,而耐久性和长期稳定性至关重要.

英文名称2,2',3,4,4',5',6-Heptachloro-1,1'-Biphenyl
中文名称2,2',3,4,4',5',6-七氯-1,1'-联苯
IUPAC名称1,2,3,5-tetrachloro-4-(2,4,5-trichlorophenyl)benzene
其它别名2,2',3,4,4',5',6-七氯联苯; 2,2',3,4,4',5',6-Heptachlorobiphenyl
CAS编号52663-69-1
MFCD编号:MFCD00152520
FDA UNII编号:RD2022B03O
分子式:C12H3Cl7分子量:395.32
产品CID: 2498502
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: KQBFUDNJKCZEDQ-UHFFFAOYSA-N
1S/C12H3Cl7/c13-5-2-7(15)6(14)1-4(5)10-8(16)3-9(17)11(18)12(10)19/h1-3H
计算化学: 氢键受体数*氢键供体数0可旋转键数1

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

上下游产品

2,4,5-trichloroiodobenzene 2,3,4,6-tetrachloroiodobenzene 2,3,4,6-tetrachloroaniline 1,2,4-Trichlorobenzene

合成工艺路线路线简述

📜2,3,4,6-四氯苯胺,三氯苯置于亚硝酸异戊酯体系中,化学反应生成 2,2',3,4,4',5',6-七氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4