CAS: 319-24-4; Methyl 2-Amino-5-Fluorobenzoate

上下游产品

2-氨基-5-氟苯甲酸 2-Amino-5-Fluorobenzoic Acid 446-08-2
2-硝基-5-氟苯甲酸甲酯 Methyl 5-Fluoro-2-Nitrobenzoate 393-85-1
5-氟-2-硝基苯甲酸 5-Fluoro-2-Nitrobenzoic Acid 320-98-9
2-氨基-5-甲氧基苯甲酸甲酯 Methyl 2-Amino-5-Methoxybenzoate 2475-80-1

2-硝基-5-氟苯甲酸甲酯置于钯 氢气,Silica Gel,乙酸乙酯,Hexanes体系中,用 甲醇 用作溶剂,化学反应 120.0H,以afforded 19.7 G (88%) Of The Title Compound As A Yellow Oil的收率获得2-氨基-5-氟苯甲酸甲酯
参考文献:Chk-1 Inhibitors
标题:Chk-1 Inhibitors
摘要:本发明涉及一种新的chk-1抑制剂及其治疗方法.

专利信息

专利号:WO-2025023769-A1
优先权日:2023-07-25
标 题:Novel synthesis method of 18f-rucaparib
发明人：CHEON CHEOL-HONG; PARK JINJAE; SEO JUAN
权利人:UNIV KOREA RES & BUS FOUND
摘要:The present invention relates to a method for efficiently preparing rucaparib for a PET image. More specifically, the present invention relates to an improved preparation method for synthesizing [18F]-rucaparib in excellent yield by means of a pathway for synthesizing a pinacol boronate derivative, which is a key intermediate, by using, as a starting material, a 2-iodoaniline derivative prepared by a novel synthesis method.

专利号:US-9944644-B2
优先权日:2013-03-14
标 题 :Octahydropyrrolopyrroles their preparation and use
发明人：PETRUKHIN KONSTANTIN; CIOFFI CHRISTOPHER; JOHNSON GRAHAM; DOBRI NICOLETA; FREEMAN EMILY; CHEN PING; CONLON MICHAEL; ZHU LEI
权利人:PETRUKHIN KONSTANTIN; CIOFFI CHRISTOPHER; JOHNSON GRAHAM; DOBRI NICOLETA; FREEMAN EMILY; CHEN PING; CONLON MICHAEL; ZHU LEI; UNIV COLUMBIA
摘要:The present invention provides compounds comprising variously substituted octahydropyrrolopyrroles, their synthesis, methods of making, methods of using, compositions and formulations thereof.

专利号:CN-113501766-A
优先权日:2021-07-07
标题 :A kind of asymmetric synthesis method of polyfunctionalized cyclopentenone derivatives containing difluoroalkyl group

专利号:CN-116178284-A
优先权日:2023-02-24
标题:Synthesis method of 2, 4-dihydroxyquinazoline and derivatives thereof

专利号:CN-113501766-B
优先权日:2021-07-07
标题:Asymmetric synthesis method of polyfunctionalized cyclopentenone derivatives containing difluoroalkyl groups