CAS: 306-37-6; N,N'-Dimethylhydrazine Dihydrochloride
化学文摘社编号306-37-6,主要用作火箭推进剂和各种化学合成物的化学化合物,由二甲基羟基和盐酸制成,形成一种在水中高度溶解的白色晶状固体,已知该化合物具有很强的减少特性,并被归类为有毒和潜在危险物质,在接触时会刺激皮肤,眼睛和呼吸系统,二氟氯化二甲基羟基在生产氢衍生物方面的作用也得到承认,这对生产药品和农业化学品十分重要,由于该化合物的毒性和潜在环境影响,处理需要严格的安全防范措施,包括使用个人防护设备和适当的通风,该化合物在航空航天和化学工业的应用突出其重要性,但也需要谨慎管理,以减轻健康和安全风险.
- 英文名称N,N'-Dimethylhydrazine Dihydrochloride
- 中文名称N,N'-二甲基肼二盐酸盐
- IUPAC名称1,2-dimethylhydrazine dihydrochloride
- 其它别名1,2-Dimethylhydrazinedihcl; Sym-Dimethylhydrazine Dihydrochloride, 99+%; Hydrazine, 1,2-Dimethyl-, Dihydrochloride; 1,2-Dimethylhydrazine Dihydrochloride (Sym-, N,N''-) 98+%; 1,2-Dimethylhydrazine Dihydrochloride, N,Nμ-Dimethylhydrazine (Sym.) Dihydrochloride; N,Nzzhlxy-Dimethylhydrazine Dihydrochloride (Sym.); Sym-Dimethylhydrazine Dihydrochloride, 99+% 10Gr; N,N'-Dimethylhydrazine Dihydrochloride
- CAS编号306-37-6
- MFCD编号:MFCD00012522
- EINECS号:206-183-5
- FDA UNII编号:8326154U0N
- 分子式:C2H10Cl2N2分子量:133.02
- 产品CID: 1292258
- 产品分类有机原料→分子砌块→脂肪链类化合物
相似化合物
16466-61-8 5394-50-3 185456-26-2物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS08 & GHS06;
注释: Health hazard & Skull and crossbones - 危险类别致癌性 类别1B
急性毒性 类别3(吸入)
急性毒性 类别3(经皮)
急性毒性 类别3(经口)
致癌性 类别2
水生慢性毒性 类别2 - 警示词Danger(危险)
- 危险描述H350 |可能致癌.
H331 |吸入会中毒.
H311 |皮肤接触会中毒.
H301 |吞咽会中毒.
H351 |怀疑致癌.
H411 |对水生生物有毒并具有长期持续影响. - 防范说明P264-P270-P330-P405-P501
- 危险等级6.1
- UN编号2811.0
- 危险品标志T,N
- 包装等级Ⅲ
- 安全声明53-45-61
- 危险类别码45-23/24/25-51/53
- WGK Germany3
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
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📜甲胺 在 三乙胺,三光气体系中,用 二氯甲烷作为反应溶剂,反应 1.25H,获得 N,N'-Dimethylhydrazine DihydroChloride
参考文献:Stabilization Of Azapeptides By Namide...H-Namide Hydrogen Bonds
标题:Stabilization Of Azapeptides By Namide...H-Namide Hydrogen Bonds
摘要:
Doi:10.1021/Acs.Orglett.1C01111
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主要参考文献
[参考文献]: Changqing Zhang, Et Al. Beta-Endorphin Cell Therapy For Cancer Prevention. Cancer Prev Res (Phila). 2015 Jan;8(1):56-67.[参考文献]: Dheeraj Mohania, Et Al. Probiotic Dahi Containing Lactobacillus Acidophilus And Bifidobacterium Bifidum Modulates The Formation Of Aberrant Crypt Foci, Mucin-Depleted Foci, And Cell Proliferation On 1,2-Dimethylhydrazine-Induced Colorectal Carcinogenesis In Wistar Rats. Rejuvenation Res. 2014 Aug;17(4):325-33.
[参考文献]: Satoru Itoh, Et Al. Assessment Of A Twice Dosing Regimen Both Before And After Partial Hepatectomy In The Rat Liver Micronucleus Test. Mutat Res Genet Toxicol Environ Mutagen. 2015 Apr:782:18-23.
[参考文献]: Satoru Itoh, Et Al. Effect Of Buprenorphine On Genotoxicity Evaluation Of Chemicals By The Rat Liver Micronucleus Test With Partial Hepatectomy. J Toxicol Sci. 2015 Feb;40(1):109-14.
合成参考文献
摘要:Journal of Toxicology and Environmental Health., 32(383), 1991 []
摘要:Carcinoma of the Colon and Antecedent Epithelium, Burdette, W.J., ed., Springfield, IL C.C. Thomas, 1970, -(267), 1970
参考文献:10.1007/bf01066534
摘要:Dawson PA, Filipe MI. A comparison of [3H]galactose and [3H]fucose uptake with the morphological and histochemical changes observed in mucous secretion in chemically induced rat colonic carcinoma. Journal of Molecular Histology. 1980 Jan;12(1):23–37. doi: 10.1007/bf01066534.
参考文献:10.1007/bf02587614
摘要:Hagihara PF, Yoneda K, Sachatello CR, Hedgecock H, Flesher JW, Ram MD, Griffen WO, Goldenberg DM. Colonic tumorigenesis in rats with 1,2-dimethylhydrazine. Dis Colon Rectum. 1980 Apr;23(3):137–40. doi: 10.1007/bf02587614.
参考文献:10.1007/bf01296986
摘要:Rogers AE, Nauss KM. Rodent models for carcinoma of the colon. Dig Dis Sci. 1985 Dec;30(12 Suppl):87S–102S. doi: 10.1007/bf01296986.
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