专利号:US-5919969-A 优先权日:1996-06-05 标 题 :Synthesis of yellow couplers 发明人:CRAWLEY MICHAEL W 权利人:EASTMAN KODAK CO 摘要:The invention provides a method of synthesis of a image-dye forming coupler of formula (I) wherein X is a substituent linked to the coupler by an atom of oxygen, sulfur or nitrogen R1 is an alkyl or aryl group, R2 is a hydrogen atom or an alkyl group; R3 to R7 are the same or different and selected from a hydrogen atom and substituent groups; which method comprises the reaction of a compound of formula (II) wherein R and R1 are the same or different and are as defined above for R1 and X is as defined above with a compound of formula (III) wherein R2 to R7 are as defined above, in the presence of an inert organic solvent.
专利号:US-6946562-B2 优先权日:2001-12-12 标 题:Synthesis of peptoid substituted azole compounds 发明人:DIEHL DONALD R; NIGER ROBERT J; SCHMITTHENNER HANS F; SONNEFELD WILLIAM J; DUNLAP RICHARD P 权利人:EASTMAN KODAK CO 摘要:Disclosed is a process for the preparation of a peptoid substituted azole compound comprising reacting an amino functionalized azole compound with a resin bound peptoid oligomer bearing a terminal halogen substituent followed by cleavage of the resultant product from the resin surface using a fluorinated organic acid in an inert solvent.
专利号:US-2003187188-A1 优先权日:2001-12-12 标 题:Synthesis of peptoid substituted azole compounds
专利号:US-5928851-A 优先权日:1996-06-20 标题:Photographic couplers which release useful groups anchiomerically and their synthesis 发明人:ALLWAY PHILIP ARTHUR 权利人:EASTMAN KODAK CO 摘要:The present invention describes an image dye-forming coupler of formula (I) wherein L is an oxymethylene or oxycarbonyl group; n is 0 or 1; COUP is a coupler moiety and R1 and R2 are the same or different and are groups selected such that (a) together with the nitrogen atom a good leaving group is formed; (b) at least one of them contains a PUG linked to an electrophilic center (E); and (c) neither R1 nor R2 is a hydrogen atom wherein the coupler is a DIAR coupler from which inhibitor is released from a coupling-off group after a timed delay which results from an additional reaction step. Such delay permits control over the time of release, rate of release and rate of diffusion of a photographically useful group (PUG) without altering the nature of the PUG itself. A method of preparing the coupler is also described wherein the two parts of the molecule can be built up separately and combined in a single reaction allowing ready access to a large variety of possible structures.
专利号:EP-1319975-A1 优先权日:2001-12-12 标 题 :Synthesis of peptoid substituted azole compounds
专利号:US-6190852-B1 优先权日:1999-12-28 标 题:Photographic element containing nitrogen heterocycle substituted cyan coupler and process 发明人:MURA ALBERT J; SCARINGE RAYMOND P; HARDER JOHN W 权利人:EASTMAN KODAK CO 摘要:Disclosed is a photographic element comprising a light-sensitive silver halide emulsion layer having associated therewith a cyan dye-forming coupler represented by Formula (I): n wherein: n each R 1 and R 3 is an independently selected substituent, m is 0 to 5, and p is 0 to 2; n X is hydrogen or a coupling-off group; n W and W 2 represent the atoms necessary to complete rings; and n R 2 is an alkyl or aryl group. n The element provides desirable hue properties and ease of synthesis.
[参考文献]: C L Goh, Et Al. Cross Sensitivity In Colour Developers. Contact Dermatitis. 1984 May;10(5):280-5. [参考文献]: C Lidén, Et Al. Contact Allergy To Colour Developing Agents In The Guinea Pig. Contact Dermatitis. 1988 Oct;19(4):290-5. [参考文献]: F Menezes Brando, Et Al. Contact Dermatitis To Cd4. Contact Dermatitis. 1985 Jan;12(1):48. [参考文献]: J H Liu, Et Al. [参考文献]: Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1990 Mar;6(1):40-1, 76-7. [参考文献]: J Sollenberg, Et Al. Contact Allergy To Colour Developing Agents. Analysis Of Test Preparations, Bulk Chemicals And Tank Solutions By High-Performance Liquid Chromatography. Derm Beruf Umwelt. 1989 Mar-Apr;37(2):47-52.
合成参考文献
摘要:Compound: Ethanol, 2-[(4-amino-3-methylphenyl)ethylamino]-, sulfate (1:1) 摘要:Marks - Marks JG, DeLeo VA. Contact and Occupational Dermatology, 2nd Ed. St. Louis: Mosby, 1997. 摘要:United States Environmental Protection Agency, Office of Pesticides and Toxic Substances., 8EHQ-1185-0575