CAS: 13100-82-8; 2-Amino-3-Sulfopropanoic Acid

该化合物是一种含有硫磺的氨酸衍生物,在各种生化过程中发挥作用;是一种极地,水溶性化合物,其特点是存在一个碳球酸组和一个全氟辛烷磺酸组,这既有助于其酸性;分子是一种由两种对映体D-和L-cysteic酸组成的种族混合物,它们是相互的镜像;这种化合物通常用于生物化学研究,可以作为其他氨酸和酸合成的前体;已知DL-Cysteic酸参与蛋白质合成,并能够影响细胞信号路径;其结构允许形成氢结,在水环境中增强溶性;此外,在与...

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498-40-8 23537-25-9 751470-47-0

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CAS号56-89-3 L-胱氨酸 | CAS号498-40-8 磺基丙氨酸 | CAS号921-01-7 D-半胱氨酸 | CAS号52-90-4 L-半胱氨酸 | CAS号7647-01-0 盐酸 | CAS号98022-26-5 3-sulfopyruvic acid | CAS号7553-56-2 碘 | CAS号59-51-8 DL-蛋氨酸 | CAS号7732-18-5 水 | CAS号302-84-1 DL-丝氨酸 | CAS号107-35-7 牛磺酸 | CAS号98022-26-5 3-sulfopyruvic acid

合成工艺路线路线简述

    📜L-胱氨酸置于水,溴体系中,化学反应生成磺基丙氨酸
    参考文献:Friedmann,1903,Vol. 3,P. 25,38
    标题:Friedmann,1903,Vol. 3,P. 25,38

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    专利信息


    专利号:US-11873305-B2
    优先权日:2020-06-30
    标题 :Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds
    发明人:ZHANG HAIMING; XU JIE; WUITSCHIK GEORG; ANGELAUD REMY; HEROLD SEBASTIAN; STUTZ ALFRED; BRUETSCH TOBIAS; BURKHARD JOHANNES
    权利人:GENENTECH INC; HOFFMANN LA ROCHE
    摘要:Provided herein are processes for the preparation of indolyl intermediates using Wenker Synthesis for the total synthesis of SERD compounds useful in the treatment of cancer.

    专利号:WO-9312076-A1
    优先权日:1991-12-13
    标题:Reagents for automated synthesis of peptide analogs
    发明人:WEBB THOMAS ROY
    权利人:CORVAS INT INC
    摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.

    专利号:US-5283293-A
    优先权日:1990-12-14
    标 题:Reagents for automated synthesis of peptide analogs
    发明人:WEBB THOMAS R
    权利人:CORVAS INC
    摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.

    专利号:US-5367072-A
    优先权日:1990-12-14
    标 题 :Reagents for automated synthesis of peptide analogs
    发明人:WEBB THOMAS R
    权利人:CORVAS INT INC
    摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.

    专利号:US-2006211083-A1
    优先权日:2005-01-21
    标题:Products and processes for in vitro synthesis of biomolecules
    发明人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
    权利人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
    摘要:Provided herein are products and processes for efficiently synthesizing biomolecules in vitro using cell-free extracts derived from mammalian cells and insect cells. In an embodiment, provided is a process for preparing a cell-free extract from insect cells and mammalian cells that efficiently synthesizes post-translationally modified target proteins (e.g., glycosylated target proteins). In some embodiments, a ribonucleic acid is synthesized in vitro that comprises a cap, a 5′ untranslated region comprising an 18S rRNA binding ribonucleotide sequence, and a target ribonucleotide sequence. It has been determined that such ribonucleic acids result in efficient in vitro synthesis of a target protein using cell-free extracts derived from non-rabbit mammalian cells and insect cells.

    专利号:US-10087221-B2
    优先权日:2013-03-21
    标题 :Synthesis of hydantoin containing peptide products
    发明人:HENKEL BERND
    权利人:SANOFI AVENTIS DEUTSCHLAND
    摘要:The present invention relates to a method of synthesizing a peptide product comprising at least one hydantoin group. The peptide product may be used as a reference material for the quality control of pharmaceutical peptides, particularly for the quality control of exendin peptides. Further, the invention relates to hydantoin building blocks, a method for manufacturing such building blocks and their use for the synthesis of peptide products.

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    合成参考文献


    参考文献:10.1007/s00216-010-3471-8
    摘要:Roeser J, Bischoff R, Bruins AP, Permentier HP. Oxidative protein labeling in mass-spectrometry-based proteomics. Analytical and Bioanalytical Chemistry. 2010 Feb 13;397(8):3441–55. doi: 10.1007/s00216-010-3471-8.
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