专利号:US-10611864-B2 优先权日:2015-09-22 标 题:Synthesis of substituted amidobenzoate compounds, the compounds obtained and the use thereof as phthalate free internal electron donor for polymerization of olefins 发明人:ZUIDEVELD MARTIN ALEXANDER; SAINANI JAIPRAKASH BRIJLAL; AL-HUMAIDAN OSAMAH; PADMANABHAN SUDHAKAR R; SHINGE PRASHANT SUKUMAR; SHETTY SHARANKUMAR G; SHAIKH ABBAS-ALLI GHUDUBHAI 权利人:SABIC GLOBAL TECHNOLOGIES BV 摘要:The present invention relates to a compound according to Formula (I) wherein R 1 is a hydrocarbyl group selected from the group consisting of alkyl, alkenyl, aryl, aralkyl, and alkylaryl groups, and one or more combinations thereof; wherein R 2 is a hydrogen atom, an aryl group or an alkyl group; and wherein R 3 , R 4 , R 5 and R 6 , are the same or different and are each independently a hydrogen atom, a halogen atom, a cyano group, an amino group, a hydrocarbyl group selected from the group consisting of alkyl, alkenyl, aryl, aralkyl, and alkylaryl groups or an alkoxy group, and one or more combinations thereof as internal electron donor and to a process for the synthesis of a compound according to Formula (I), wherein R 1 is a hydrocarbyl group selected from the group consisting of alkyl, alkenyl, aryl, aralkyl, alkoxycarbonyl and alkylaryl groups, and one or more combinations thereof; wherein R 2 is a hydrogen atom or an alkyl group; wherein R 3 , R 4 , R 5 and R 6 , are the same or different and are each independently selected from a group consisting of a hydrogen atom; a hydrocarbyl, preferably, said process comprising the step of reacting a compound according to Formula (II) [R 1 —C(â•?O)Cl] with a compound according to Formula (III) to obtain the compound according to Formula (I) and to the use of these compounds as internal donor in Ziegler-Natta catalysis of lefins.
专利号:US-6177572-B1 优先权日:1997-08-20 标题 :Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use 发明人:WANG FENGJIANG 权利人:SEPRACOR INC 摘要:Methods for preparing benzoxazoles and benzothiazoles on solid supports. Substituted benzothiazoles and benzoxazoles, libraries of the compounds, and methods of using the compounds are also disclosed.
专利号:US-7550510-B2 优先权日:2001-07-06 标 题 :Solid phase synthesis of arylretinamides 发明人:CURLEY JR ROBERT W; MERSHON SERENA M; BARNETT DEREK W; CLAGETT-DAME MARGARET; CHAPMAN JASON S 权利人:WISCONSIN ALUMNI RES FOUND 摘要:A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reacting retinoic acid with the activated chlorinating reagent to provide retinoyl chloride; adding pyridine and a select arylamine to the resulting mixture; and stirring the resulting mixture for a time and at a temperature sufficient for the select arylamine to react with the retinoyl chloride and provide the arylretinamide. Also provided, are select arylretinamides that can be prepared by the present method, and methods of using such arylretinamides to induce apoptosis in cancer cells.
专利号:US-2025034123-A1 优先权日:2021-12-28 标题 :A synthesis method of benzoxazole based optical brighteners 发明人:BASALP MEHMET; GUREL GOKAY 权利人:AKDENIZ CHEMSON KIMYA SANAYI VE TICARET ANONIM SIRKETI 摘要:The present invention is a synthesis method for benzoxazole based optical brighteners characterized by comprising the steps of; placing in a reactor vessel at least one acid selected from thiophene-2,5-dicarboxylic acid or stilbene-4,4′-dicarboxylic acid, at least one catalyst and at least one compound selected from liquid paraffin and/or xylene; obtaining a mixture by adding 2-amino-4-tert-butylphenol in the reactor vessel if the said at least one acid is selected as thiophene-2,5-dicarboxylic acid or adding 2-aminophenol in the reactor vessel if the said at least one acid is selected as stilbene-4,4′-dicarboxylic acid; mixing the obtained mixture for a first time period under nitrogen atmosphere to carry out the synthesis reaction of benzoxazole based optical brighteners; during mixing the obtained mixture, increasing the temperature of the said mixture gradually to a first temperature; after mixing obtained mixture for the first time period, filtering the mixture; after filtering the mixture, obtaining a first benzoxazole based optical brightener or a second benzoxazole based optical brightener.
专利号:WO-2017050870-A1 优先权日:2015-09-22 标题 :Synthesis of substituted amidobenzoate compounds, the compounds obtained and the use thereof as phthalate free internal electron donor for polymerization of olefins
专利号:US-2018273661-A1 优先权日:2015-09-22 标题 :Synthesis of substituted amidobenzoate compounds, the compounds obtained and the use thereof as phthalate free internal electron donor for polymerization of olefins
摘要:Schnürch, M.; Hämmerle, J.; Stanetty, P., Science of Synthesis Knowledge Updates, (2010) 1, 165. 摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198 参考文献:10.1523/jneurosci.0835-08.2008 摘要:Narayanan R, Johnston D. The h Channel Mediates Location Dependence and Plasticity of Intrinsic Phase Response in Rat Hippocampal Neurons. J. Neurosci. 2008 May 28;28(22):5846–60. doi: 10.1523/jneurosci.0835-08.2008.