CAS: 11103-86-9; ——
- 英文名称——
- 中文名称氢氧化铬酸锌钾
- IUPAC名称potassium;dizinc;bis(dioxido(dioxo)chromium);hydroxide
- 其它别名chromic acid, potassium zinc salt (2:2:1); potassium zinc chromate hydroxide; zinc chromates; zinc yellow; potassiumzincchromate; zinc potassium chromate 6; Chromate,hydroxy°Ctaoxodizincatedi-,potassium
- CAS编号11103-86-9
- EINECS号:234-329-8
- 分子式:CrH2KO5Zn-3分子量:238.49
- 产品CID: 146580
- 产品分类Metals → Chromium Compounds, Inorganic | Carcinogens
物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS08 & GHS06 & GHS09;
注释: Health hazard & Skull and crossbones & Environment - 危险类别致癌性 类别1A
致突变性 类别2
生殖毒性 类别2
急性毒性 类别2(吸入)
急性毒性 类别4(经口)
特定目标器官毒性 - 单次接触 类别3
皮肤致敏 类别1
水生急性毒性 类别1
水生慢性毒性 类别1
皮肤致敏 类别1B
特定目标器官毒性-重复接触 类别2
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
呼吸道致敏 类别1 - 警示词Danger(危险)
- 危险描述H350 |可能致癌.
H341 |怀疑导致遗传缺陷.
H361fd |怀疑会影响生育能力. 怀疑对胎儿造成损害.
H330 |吸入致命.
H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H317 |可能引起皮肤过敏反应.
H400 |对水生生物毒性极大.
H410 |对水生生物毒性极大并具有长期持续影响.
H361 |怀疑对生育能力或胎儿造成损害.
H373 |长期或反复接触可能损害器官.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H334 |吸入可能引起过敏或哮喘症状或呼吸困难. - 防范说明P273-P391-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501-P273-P391-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P201-P202-P281-P308+P313-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501
- 危险等级6.1(a)
- UN编号3288
- 包装等级II
- 安全声明IDENTIFICATION AND USE: Zinc potassium chromate is a green-to-yellow powder. Zinc chromates are employed primarily in priming paints used for metals, for which they provide resistance against corrosion. HUMAN EXPOSURE AND TOXICITY: A small cohort of Norwegian male workers /were studied/ from a company which produced zinc chromate paint. They found 3 cases of bronchial carcinoma (in workers aged 41, 51, and 59) where only 0.079 was expected for the total period of observation. The authors indicated that the three cases had six to nine years of exposure to zinc chromate dust levels of approximately 0.5 to 1.5 mg Cr/cu m. Two of the three carcinomas were found in smokers. There was also one case of nasal cancer in a man with a total of 3 month of exposure. Zinc chromate spray painters and electroplaters at two large aircraft maintenance facilities were studied. The relative excess for respiratory cancer among spray painters (21 observed vs 11.4 expected) was statistically significant. Incidence of chrome dermatitis has been estimated at widely varying levels 0.1-0.6 % in aircraft workers using zinc primer paint. ANIMAL STUDIES: An increased incidence of squamous cell carcinomas of the lung in rats subjected to bronchial implants of stainless steel pellets coated with zinc potassium chromate was reported. Zinc chromates enhanced the viral transformation of Syrian hamster secondary embryo cells by simian adenovirus SA7. | Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produced during reoxidation of pentavalent chromium by hydrogen peroxide molecules present in the cell. Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, chromium-DNA adducts, chromosomal aberrations and alterations in cellular signaling pathways. It has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. It can also cause transcriptional repression by cross-linking histone deacetylase 1-DNA methyltransferase 1 complexes to CYP1A1 promoter chromatin, inhibiting histone modification. Chromium may increase its own toxicity by modifying metal regulatory transcription factor 1, causing the inhibition of zinc-induced metallothionein transcription. (A12, L16, A34, A35, A36, L48, L49, A49)
- 危险类别码May cause skin sensitization; [eChemPortal: ERMA] See Zinc chromate. See Chromium and linked occupational diseases.
欧盟法规
REACH注册ECHA物质ECHA物质欧盟授权物质清单C&L通报REACH预注册欧盟候选物质清单合成工艺路线路线简述
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
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合成参考文献
摘要:American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH 2015, p. 61
摘要:ECHA; Search for Chemicals. Potassium hydroxyoctaoxodizincatedichromate(1-) (CAS 11103-86-9) Registered Substances Dossier. European Chemical Agency. Available from, as of Dec 16, 2015:
摘要:USEPA/Office of Water; Federal-State Toxicology and Risk Analysis Committee (FSTRAC). Summary of State and Federal Drinking Water Standards and Guidelines (11/93) To Present
摘要:Mackison, F. W., R. S. Stricoff, and L. J. Partridge, Jr. (eds.). NIOSH/OSHA - Occupational Health Guidelines for Chemical Hazards. DHHS(NIOSH) Publication No. 81-123 (3 VOLS). Washington, DC: U.S. Government Printing Office, Jan. 1981., p. 1
摘要:Huntsman Pigments Americas LLC. Available from, as of Dec 16, 2015: https://hpigments.com/
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