CAS: 87-09-2; Penicillin O

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    上下游产品

    allylsulfanyl-acetic acid allylmercapto-acetic acid-(2-hydroxy-ethylamide) S)-2t-[(R)-(2-allylsulfanyl-acetylamino)-(5-carboxy-pentylcarbamoyl)-methyl]-5,5-dimethyl-thiazolidine-4r-carboxylic acid; bis-benzylamine salt(4S)-2t-[(R)-(2-allylsulfanyl-acetylamino)-(5-carboxy-pentylcarbamoyl)-methyl]-5,5-dimethyl-thiazolidine-4r-carboxylic acid; bis-benzylamine salt

    合成工艺路线路线简述

      📜(烯丙基硫代)乙酸,Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成 青霉素o
      参考文献:Behrens Et Al.,Journal Of Biological Chemistry,1948,Vol. 175,P. 801
      标题:Behrens Et Al.,Journal Of Biological Chemistry,1948,Vol. 175,P. 801

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      专利信息


      专利号:US-7662401-B2
      优先权日:2002-04-08
      标 题 :Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase
      发明人:MAHE YANN; MEYBECK ALAIN
      权利人:OREAL
      摘要:The present invention relates to the cosmetic or pharmaceutical use of an extract of a nonfruiting nonphotosynthetic filamentous bacterium in a composition containing a cosmetically or pharmaceutically acceptable medium, as an agent increasing the endogenous synthesis of superoxide dismutase, in particular for preventing and/or limiting the formation of free radicals and/or removing the free radicals present in cells; in addition, the invention relates to a composition comprising at least one extract of Vitreoscilla filiformis and lycopene.

      专利号:WO-9636627-A1
      优先权日:1995-05-19
      标 题 :Collection of activated glycoside compounds and their biological use
      发明人:ANDERSON MARK BRIAN; MUSSER JOHN H
      权利人:GLYCOMED INC
      摘要:The present invention relates to the field of combinatorial carbohydrate chemistry and involves the modification of organic molecules and/or the synthesis of large numbers of products comprising carbohydrate and/or glycominetic entities. More specifically, the present invention relates to activated carbon glycosides useful for the modification of organic molecules by incorporation of carbohydrate units, providing the synthesis of large numbers of products having novel chemical characteristics. The present invention further relates to methods for the generation of chemical compounds comprising carbon glycosides. Methods are disclosed to provide large arrays of molecules and to identify species that act as agonists or antagonists of various biological, chemical, and other activities.

      专利号:WO-0032619-A1
      优先权日:1998-11-30
      标题:Methods and compositions for identification of inhibitors of ribosome assembly
      发明人:DAMMEL CAROL S; WATSON JULIE C
      权利人:RIBOGENE INC
      摘要:The invention provides a means for identifying novel antibiotics by screening for compounds that inhibit bacterial ribosome assembly and ribosomal protein synthesis, which comprises the screening of test compounds to identify those that inhibit the activity of a bacterial ribosomal protein. The in vitro and in vivo assays detect (a) increased translation of a reporter mRNA that is normally repressed in the presence of a ribosomal protein, (b) increased growth in cells that over-express ribosomal protein, and (c) decreased binding of the ribosomal protein to its target RNA. The invention encompasses the (a) methods of screening and testing compounds by the above methods, (b) compounds that are identified in the assay which inhibit ribosome assembly and protein synthesis and (c) methods for treatment using said compounds.

      专利号:US-2003224077-A1
      优先权日:2002-04-08
      标 题:Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase

      专利号:US-2007237746-A1
      优先权日:2002-04-08
      标题:Administration of extracts of nonfruiting nonphotosynthetic filamentous bacteria for increasing the endogenous synthesis of superoxide dismutase

      专利号:US-8722649-B2
      优先权日:2007-06-15
      标 题 :Alpha-chloro and alpha-bromo phosphonate analogs of lysophosphatidic acid and methods of making and using thereof
      发明人:PRESTWICH GLENN; TIGYI GABOR; JIANG GUOWEI; YANG GUANGHUI; GAJEWIAK JOANNA; ZHANG HONGLU; XU XIAOYU
      权利人:PRESTWICH GLENN; TIGYI GABOR; JIANG GUOWEI; YANG GUANGHUI; GAJEWIAK JOANNA; ZHANG HONGLU; XU XIAOYU; UNIV UTAH RES FOUND; UNIV TENNESSEE RES FOUNDATION
      摘要:Described herein is the synthesis and pharmacology of a series of α-substituted methylene phosphonate analogs, in which the α-CH 2 moiety is replaced with CHCl or CHBr.

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