CAS: 6329-61-9; Decahydroisoquinoline

相似化合物

90949-02-3 947767-62-6 2744-08-3

上下游产品

isoquinoline 1,2,3,4-tetrahydroisoquinoline N-ethoxycarbonyl-cis-decahydroisoquinoline *,8aS*)-1,2,3,4,4a,5,6,7,8,8a-perhydroisoquinoline-1,3-dione(4aS*,8aS*)-1,2,3,4,4a,5,6,7,8,8a-perhydroisoquinoline-1,3-dione5,6,7,8-tetrahydroisoquinoline H-spiro[isoquinoline-2,1'-piperidinium]; bromide3,4-dihydro-1H-spiro[isoquinoline-2,1'-piperidinium]; bromide

📜1,2,3,4-四氢异喹啉-3-羧酸 反应生成 十氢异喹啉
参考文献:Patterns Of Religious Practice And Belief In The Last Year Of Life
标题:Patterns Of Religious Practice And Belief In The Last Year Of Life
摘要:Objectives. Although It Is Frequently Assumed That Issues Of Religious Faith Become More Salient At The End Of Life. There Is Little Or No Population-Based Empirical Evidence Testing This Assumption.Methods. Using Data From The New Haven Site Of The Established Populations For Epidemiologic Studies Of The Elderly (N = 2.812). The Authors Examined Self-Reports Of Attendance At Services. Self-Ratings Of Religiousness,And Strength And Comfort Felt From Religion For Respondents Who Did And Did Not Die Within 12 Months Following An Interview. Religiousness Was Assessed At Baseline (1982) And In Follow-Up Interviews In 1985,1988,And 1994. Cross-Sectional Comparisons Of Levels Of Religiousness Were Made Among Persons In Their Last 6 Months Of Life,Persons In Their Last 12 Months Of Life,And Persons Who Survived 12 Months,And Longitudinal Comparisons Were Made With Religiousness At The Previous Wave.Results. After Adjusting For Age,Sex,Education. Marital Status,Religious Affiliation,And A Set Of Health Status Measures. The Authors Found That Although Attendance At Religious Services Declined Among The Near-Deceased,This Group Showed Either Stability Or A Small Increase In Feelings Of Religiousness And Strength/comfort Received From Religion. Overall Levels Of Attendance And Religious Feelings Were High For This Religiously Diverse Sample.Discussion. Community Studies Of Respondents In Their Last Year Of Life Are Rare. In This Sample,Religious Involvement Appears To Continue Throughout The Last Months Of Life.
DOI:10.1093/geronb/56.6.S326

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-4902817-A
优先权日:1987-09-17
标 题 :Process for the synthesis of alpha n alkylated amino acids and esters thereof, application to the synthesis of carboxyalkyl dipeptides
发明人：VINCENT MICHEL; BALIARDA JEAN; MARCHAND BERNARD; REMOND GEORGES
权利人:ADIR
摘要:Stereoselective process for the industrial synthesis of compounds of formula (I): ##STR1## where R 1 is linear or branched lower alkyl with 1 to 6 carbon atoms, n R 2 is a linear or branched lower alkyl with 1 to 4 carbon atoms, n employing inexpensive starting materials and obtaining optimum yields. n Application to the synthesis of carboxyalkyl dipeptides.

专利号:WO-2023102600-A1
优先权日:2021-12-06
标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom
发明人：ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI
权利人:NEWSOUTH INNOVATIONS PTY LTD
摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.

专利号:US-11220513-B2
优先权日:2015-04-30
标题:Chromium-mediated coupling and application to the synthesis of halichondrins
发明人：KISHI YOSHITO; YAN WUMING; LI JINGWEI; LI ZHANJIE; YAHATA KENZO
权利人:HARVARD COLLEGE
摘要:The present invention provides unified synthesis of the C1-C19 building blocks of halichondrins and analogs thereof using selective coupling of poly-halogenated nucleophiles in chromium-mediated coupling reactions. The present invention also provides a practical and efficient synthesis of C20-C38 building blocks of halichondrins and analogs thereof. Also provided herein are general methods of selective activation and coupling of poly-halogenated analogs with an aldehyde. The provided coupling reactions are selective for halo-enone and halo-acetylenic ketal over vinyl halide and halide attached to a sp hybridized carbon. The provided efficient selective coupling reactions can allow easy access to the C1-C19 building blocks and C20-C38 building blocks of halichondrins and analogs thereof with limited or no purification or separation of the intermediates.

专利号:EP-0309324-B1
优先权日:1987-09-17
标 题:Process for the preparation of n-alkylated amino acids and their esters, use in the synthesis of carboxyalkyl dipeptides
摘要:Process for industrial synthesis of the derivative of formula (I): and their addition salts with an inorganic or organic acid or base, in which: R1 is linear or branched lower alkyl (of 1 to 6 carbon atoms), R2 is hydrogen or a linear or branched lower alkyl group (of 1 to 4 carbon atoms). Application to the industrial synthesis of carboxyalkyl dipeptides.

专利号:US-5484949-A
优先权日:1993-01-29
标题:Method for the synthesis of α β-unsaturated ketones
发明人：TSUKASHIMA KEIICHI; NAKAJIMA MASASHI; FUJIMARU MASAYOSHI; SUZUKI KENJI
权利人:NIPPON SODA CO
摘要:The present invention relates to a method for the synthesis of alpha , beta -unsaturated ketones which comprises, in the method for the synthesis of alpha , beta -unsaturated ketones represented by general formula reacting aldehydes represented by general formula R1CHO (where R1 is as defined above) with alkali metal salt of acetoacetic acid represented by general formula sence as a catalyst of 3-azabicyclo[3,2,2]nonane, a cyclic secondary amine represented by general formula (1) (1) a cyclic secondary amine represented by general formula (2) (2) (where, l is 1 or more and up to 6, a ring with N is a 6-membered, 7-membered or 8-membered ring, the two neighbors of N are methylene, R3 is a lower alkyl group, its substitution position is at a carbon atom other than two those adjacent to N, and is an alicyclic group or a phenol group), or a secondary amine represented by general formula (3) CH3NHCH2R4(3) in a mixuture solvent of water and water-insoluble organic solvent, while keeping the pH constant with mineral acid, and by adjusting an amount of water.