CAS: 61548-81-0; (1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl Methanesulfonate

英文名称(1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl Methanesulfonate
中文名称拉米夫定杂质26
CAS编号61548-81-0
MFCD编号:MFCD30531949
分子式:C11H22O3S分子量:234.36
产品CID: 1597474
产品分类分析化学 → 标准品 → 药典标准品和杂质标准品

相似结构搜索
InChIKey: JHBDQWDYNMJVIB-OUAUKWLOSA-N
1S/C11H22O3S/c1-8(2)10-6-5-9(3)7-11(10)14-15(4,12)13/h8-11H,5-7H2,1-4H3/t9-,10+,11-/m1/s1
计算化学: 氢键受体数3.0氢键供体数0.0可旋转键数3.0

MSDS等安全信息

上下游产品

menthol methanesulfonyl chloride (-)-menthol 1-phenylselenenylneomenthane 2‐azido‐1‐isopropyl‐4‐methylcyclohexane trans-1,4-menthane R)-trans-p-menth-2-ene(1R)-trans-p-menth-2-ene

合成工艺路线路线简述

合成目标产物 Emtricitabine 主要起始原料 L-Menthol And Methanesulfonyl Chloride
2216-51-5 = 61548-81-0
反应条件:1.1R:Et3N,S:Ch2Cl2,30 Min,Rt1.2S:Ch2Cl2,20 Min,0°C; 0°C -> Rt; 2 H,Rt1.3R:Nh4Cl,S:H2O
标题:Survey Of New,Small-Molecule Isatin-Based Oxindole Hybrids As Multi-Targeted Drugs For The Treatment Of Alzheimers Disease
作者:By Marques,Carolina S. Et Al
参考文献:Synthesis 日期:2022 卷标:54(19) 页码:4304-4319]

2216-51-5 = 61548-81-0
反应条件:1.1R:Et3N,S:Ch2Cl2,2 H,Rt
标题:Synthesis And In Vitro Antibacterial Evaluation Of Novel 4-Substituted 1-Menthyl-1,2,3-Triazoles
作者:By Khaligh,Pooneh Et Al
参考文献:Chemical & Pharmaceutical Bulletin 日期:2016 卷标:64(11) 页码:1589-1596]

2216-51-5 = 61548-81-0
反应条件:1.1R:C5H5N,S:Ch2Cl2,0°C; 0°C -> Rt; 4 H,Rt
标题:Catalytic Coupling Of Carbon Dioxide With Terpene Scaffolds: Access To Challenging Bio-Based Organic Carbonates
作者:By Fiorani,Giulia Et Al
参考文献:Chemsuschem 日期:2016 卷标:9(11) 页码:1304-1311]

2216-51-5 + 421-20-5 + 2374-61-0 = 61548-81-0
反应条件:1.172 H,50°C2.1R:S:Ch2Cl2,S:Mecn
标题:N,N-Diethyl-N-Methyl-N-(Methylsulfonyl)Ammonium Fluorosulfate
作者:By King,James F.
参考文献:E-Eros Encyclopedia Of Reagents For Organic Synthesis 日期:2001 卷标:From E-Eros Encyclopedia Of Reagents For Organic Synthesis 页码:1Pp.]

2216-51-5 = 61548-81-0
反应条件:1.1S:C5H5N
标题:Synthesis And Olfactory Properties Of 2-Substituted And 2,3-Annulated 1,4-Dioxepan-6-Ones
作者:By Plummer,Christopher M. Et Al
参考文献:Asian Journal Of Organic Chemistry 日期:2015 卷标:4(10) 页码:1075-1084]

2216-51-5 = 61548-81-0
反应条件:1.1R:Et3N,S:Ch2Cl2,Rt -> 0°C; 20 Min,0°C; 2 H,Rt1.2R:HCL,S:H2O
标题:Inversion Of Secondary Chiral Alcohols In Toluene With The Tunable Complex Of R3Nr'Cooh
作者:By Shi,Xiao-Xin Et Al
参考文献:Tetrahedron: Asymmetry 日期:2010 卷标:21(3) 页码:277-284]

2216-51-5 = 61548-81-0
反应条件:1.1C:1003-67-4,S:Ch2Cl2,3 H,Rt1.2R:HCL,S:H2O,Rt
标题:Amine-Free O -Sulfonylation By A Combination Of 4-Methylpyridine N -Oxide Catalyst With 4å Molecular Sieves
作者:By Yoshida,Keisuke Et Al
参考文献:Synlett 日期:2022 卷标:33(15) 页码:1570-1574]

2216-51-5 = 61548-81-0
反应条件:1.1R:Et3N,S:Ch2Cl2,30 Min,Rt; Rt -> 0°C1.2S:Ch2Cl2,< 20 Min,0°C; 2 H,Rt1.3R:Nh4Cl,S:H2O
标题:Enantioselective Rh(I)-Catalyzed Additions Of Arylboronic Acids To N-1,2,3-Triazole-Isatin Derivatives: Accesing N-(1,2,3-Triazolmethyl)-3-Hydroxy-3-Aryloxindoles
作者:By Burke,Anthony And Marques,Carolina
参考文献:Chemcatchem 日期:2016 卷标:8(22) 页码:3518-3526]

2216-51-5 = 61548-81-0
反应条件:1.1R:Et3N,S:Ch2Cl2,0°C; 20 Min,Rt; 3 H,Rt1.2R:HCL,S:H2O,Rt
标题:Synthesis And Structures Of (-)Menthyl And (+)Neomenthyl Substituted Enantiopure Bis(1,2,3-Triazol-5-Ylidene)Pdi2 Complexes And Peppsi Type (1,2,3-Triazol-5-Ylidene)(Pyridine)Pdi2 Complexes. Comparison Of Catalytic Activities For C-C Coupling
作者:By Mohan,Arumugam Et Al
参考文献:Journal Of Organometallic Chemistry 日期:2015 卷标:799-800 页码:115-121]

2216-51-5 = 61548-81-0
反应条件:1.1R:Et3N,S:Ch2Cl2,16 H,Rt
标题:Diastereoselective Desymmetrization Of Diarylphosphinous Acid-Borane Amides Under Birch Reduction
作者:By Stankevic,Marek
参考文献:Organic & Biomolecular Chemistry 日期:2015 卷标:13(21) 页码:6082-6102]

2216-51-5 = 61548-81-0
反应条件:1.1R:Et3N,S:Ch2Cl2,30 Min,0°C; 2 H,Rt
标题:Oxidative Breakdown Of Iodoalkanes To Catalytically Active Iodine Species: A Case Study In The α-Tosyloxylation Of Ketones
作者:By Guo,Wusheng Et Al
参考文献:Chemcatchem 日期:2014 卷标:6(2) 页码:468-472]

2216-51-5 = 61548-81-0
反应条件:1.1R:Et3N,S:Ch2Cl2,0°C; 3 H,Rt1.2R:Nacl,S:H2O,5 Min,Rt
标题:Palladium(Ii)- And Rhodium(I)-N-Heterocyclic Carbene Complexes Derived From Menthol: Synthesis And Characterisation
作者:By Gu,Zheng-Song Et Al
参考文献:Journal Of Chemical Research 日期:2012 卷标:36(11) 页码:641-643]

2216-52-6 = 61548-81-0
反应条件:1.1
标题:Synthesis Of Chiral Alkanols By Resolution And Inversion Methods
作者:By Eames,J.
参考文献:Science Of Synthesis 日期:2008 卷标:36 页码:341-421]

2216-51-5 = 61548-81-0
反应条件:1.1S:Ch2Cl2,Rt -> 0°C; 20 Min,0°C1.2R:Et3N,0°C; 24 H,20°C
标题:Syntheses Of C-1 Axial Derivatives Of L-Menthol
作者:By Dillner,Debra K.
参考文献:Organic Preparations And Procedures International 日期:2009 卷标:41(2) 页码:147-152]

2216-51-5 = 61548-81-0
反应条件:1.1R:1-Methylimidazole,R:Et3N,S:Phme,1 H,20-25°C
标题:General,Robust,And Stereocomplementary Preparation Of β-Ketoester Enol Tosylates As Cross-Coupling Partners Utilizing Tscl - N-Methylimidazole Agents
作者:By Nakatsuji,Hidefumi Et Al
参考文献:Organic Letters 日期:2008 卷标:10(11) 页码:2131-2134

📜Methane Sulfonyl Chloride,L-薄荷醇置于三乙胺体系中,用四氢呋喃,水作为反应溶剂,化学反应生成拉米夫定杂质26
参考文献:Synthesis Of Cycloalkyldiarylphosophines
标题:Synthesis Of Cycloalkyldiarylphosophines
摘要:含有两个芳基基团和一个与磷原子键合的烷基取代环烷基基团的膦化合物是通过将碱金属二芳基膦化物与含有2-位置烷基基团的单烷基或多烷基取代环烷基甲磺酸酯或对甲苯磺酸酯反应而形成的,反应在这些反应物可溶的液体反应介质中进行.这个过程避免了与以往已知的生产这类膦化合物的工艺技术相关的复杂性.这些膦化合物可用作制备贵金属催化剂的配体.