CAS: 58274-56-9; 5-Hydroxy-6-Methoxy-3-(4-Methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One
该化合物是一种自然产生的化合物,主要来自Kakkalide植物物种,以其潜在的药性而著称,该物质被归类为氟虫素,一种多酚化合物,显示各种生物活动,包括抗氧化剂,抗炎和抗微生物效应.Kakkalide的特点是其独特的化学结构,通常包括多种有助于其再活和与生物系统互动的氢化物组.该化合物经常被研究其潜在的治疗用途,特别是在传统医学中.此外,Kakkalide可能表现出有机溶剂溶解性,其稳定性可能受到诸如pH和温度等环境因素的影响.对Kakkalide的研究继续探索其药性特性以及健康和健康的潜在用途.然而,关于其毒性和安全特征的详细研究对于了解其是否适合各种应用至关重要.
- 英文名称5-Hydroxy-6-Methoxy-3-(4-Methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One
- 中文名称葛花苷
- IUPAC名称5-hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
- 其它别名Kakkalide; 5-Hydroxy-6-Methoxy-3-(4-Methoxyphenyl)-7-[(6-O-Beta-D-Xylopyranosyl-Beta-D-Glucopyranosyl)Oxy]-4H-1-Benzopyran-4-One; 4H-1-Benzopyran-4-One, 5-Hydroxy-6-Methoxy-3-(4-Methoxyphenyl)-7-[(6-O-β-D-Xylopyranosyl-β-D-Glucopyranosyl)Oxy]-; Kakkalide Usp/ep/bp; 5-Hydroxy-6-Methoxy-3-(4-Methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One; Kakkalide,Inhibitor,Inhibit
- CAS编号58274-56-9
- MFCD编号:MFCD09970384
- 分子式:C28H32O15分子量:608.55
- 产品CID: 1557626
- 产品分类生物化工
物理性质
- 熔点250-252 °C
- 沸点902.0±65.0 °C(预测)
- 闪点296.9 °C
- 密度1?+-.0.1 g/cm3(预测)
- pKa:6.08±0.20(预测)
- PSA:227.2
- LogP:-0.292 (est)
- 折射率1.693
- 蒸汽压4.92E-35 mmHg at 25 °C
- 外观形态白色至类白色固体
- 储存条件Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
- 产品应用该化合物用作减少酒精中毒,防止肝损伤;通过调整内分泌系统,改善酒精引起的代谢异常;通过抑制与活性氧物种有关的炎症,改善内皮泌尿胰岛素抗药性.
MSDS等安全信息
合成工艺路线路线简述
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Quantitative analysis of two isoflavones in Pueraria lobata flowers from eleven Chinese provinces using high performance liquid chromatography Meicun Yao, Yiting Liao, George Q Li, Francis CP Law, Yi Tang Chin Med. 2010;
5: 14. Published online 2010 Apr 23. doi: 10.1186/1749-8546-5-14 2020;
2020: 4258156. Published online 2020 Apr 14. doi: 10.1155/2020/4258156 2018 Nov; 10(11): 1580. Published online 2018 Oct 26. doi: 10.3390/nu10111580 R. Mahadik J Tradit Complement Med. 2015 Oct; 5(4): 207–227. Published online 2015 Jan 28. doi: 10.1016/j.jtcme.2014.11.041 2017 Mar; 9(3): 212. Published online 2017 Feb 28. doi: 10.3390/nu9030212 2015;
合成参考文献
参考文献:10.1248/bpb.29.1202
摘要:Shin JE, Bae EA, Lee YC, Ma JY, Kim DH. Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. Biol Pharm Bull. 2006 Jun;29(6):1202–6. doi: 10.1248/bpb.29.1202.
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